Abdominal Pain News and Research

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Abdominal pain is traditionally described by its chronicity (acute or chronic), its progression over time, its nature (sharp, dull, colicky), its distribution (by various methods, such as abdominal quadrant (left upper quadrant, left lower quadrant, right upper quadrant, right lower quadrant) or other methods that divide the abdomen into nine sections), and by characterization of the factors that make it worse, or alleviate it.

Direct action of SARS-CoV-2 on organs may lead to exacerbated inflammatory response in pediatric patients

Besides common symptoms such as fever, cough and respiratory distress, some children have an atypical form of COVID-19 known as multisystem inflammatory syndrome in children (MIS-C), characterized by persistent fever and inflammation of several organs, such as the heart and intestines, as well as the lungs to a lesser extent.

1 Jun 2021

Scientists explain possible causes of anaphylaxis following mRNA COVID-19 vaccination

New research from a team of scientists at the Centre for Research in Molecular Modeling, Department of Chemistry and Biochemistry, Concordia University in Canada, has aimed to determine the potential causes of anaphylaxis or allergic reactions reported in some individuals after receiving COVID-19 vaccines, including the mRNA vaccines by Pfizer-BioNTech and Moderna.

1 Jun 2021

Tens of thousands of women utilize the emergency department for fibroid symptoms

Fibroid symptoms, such as heavy menstrual bleeding and abdominal pain, are increasingly driving women to the emergency room.

1 Jun 2021

Mass screening reveals significantly higher numbers of coeliac disease cases in children

Mass screening of school age children has led to significantly higher numbers of coeliac disease cases being diagnosed, according to a new study presented today at the 6th World Congress of Pediatric Gastroenterology, Hepatology and Nutrition.

29 May 2021

Loss of gut epithelial barrier responsible for COVID-19-related MIS-C in children, suggests study

A new paper in the Journal of Clinical Investigation reports that this condition is due to damage to the gut, mediated by a decrease in the protein called zonulin, which is responsible for the integrity of the gut epithelial barrier. Reduced zonulin levels are found in several inflammatory and autoimmune conditions.

28 May 2021

Study shows how rare but serious post-COVID-19 complication develops in children, adolescents

A multidisciplinary team from MassGeneral Hospital for Children (MGHfC), Brigham and Women's Hospital and other institutions have identified the mechanism of how an extremely rare but serious post-COVID-19 complication develops in children and adolescents.

26 May 2021

Risk factors for rare COVID-19 complications in children (MIS-C)

While the earlier waves of COVID-19 relatively spared children, some of the affected children have developed a systemic inflammatory condition, with occasionally fatal outcomes. Called multisystem inflammatory syndrome in children (MIS-C), its pathogenesis and risk factors are the subject of a new study on the medRxiv* preprint server.

21 May 2021

Western diet impairs the gut immune system, could increase risk of inflammatory bowel disease

Eating a Western diet impairs the immune system in the gut in ways that could increase risk of infection and inflammatory bowel disease, according to a study from researchers at Washington University School of Medicine in St. Louis and Cleveland Clinic.

18 May 2021

Investigational drug reduced triglycerides in patients with severe hypertriglyceridemia, acute pancreatitis

The investigational drug evinacumab reduced triglycerides in patients with severe hypertriglyceridemia (sHTG) and a history of hospitalizations for acute pancreatitis in a phase 2 global study led by Mount Sinai.

17 May 2021

Guidance on diagnosis and management of cerebral venous sinus thrombosis after a COVID-19 vaccine

Last Friday, the Centers for Disease Control and Prevention and the U.S. Food & Drug Administration lifted the pause in administration of the Johnson & Johnson (Janssen) COVID-19 vaccine in the U.S.

29 Apr 2021

Study can help improve the clinical handling of giardiasis cases

Researchers from the degree in medicine of the CEU Cardenal Herrera of Castellón, in collaboration with the Paediatrics and Microbiology Departments of the University Hospital of La Plana in Villarreal, have conducted an observational study of the cases of giardiasis among children under 15 diagnosed between 2012 and 2019 in the Departamento 3 de Salud records of Castellón province.

27 Apr 2021

Researchers aim to better understand clinical features associated with COVID-19 mortality

To better understand the COVID-19 clinical feaures associated with mortality, an interdisciplinary team of researchers has investigated important factors and their influence on a patient’s death.

22 Apr 2021

From rotten teeth to advanced cancer, patients feel the effects of treatment delays

With medical visits picking up again among patients vaccinated against Covid-19, health providers are starting to see the consequences of a year of pandemic-delayed preventive and emergency care as they find more advanced cancer and rotting and damaged teeth, among other ailments.

20 Apr 2021

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

Today, the U.S. Food and Drug Administration approved Opdivo (nivolumab), in combination with certain types of chemotherapy, for the initial treatment of patients with advanced or metastatic gastric cancer, gastroesophageal junction cancer and esophageal adenocarcinoma.

16 Apr 2021

GACVS COVID-19 reviews rare cases of blood clots following AstraZeneca COVID-19 vaccination

The COVID-19 subcommittee of the WHO Global Advisory Committee on Vaccine Safety (GACVS) has reviewed reports of rare cases of blood clots with low platelets following vaccination with the AstraZeneca COVID-19 vaccine (including Covishield) since their onset a few weeks ago.

12 Apr 2021

Study compares performance of open-label placebo to blinded placebo in IBS patients

For decades, the power of the placebo effect was thought to lie in patients' belief that they were -- or at least, could be -- receiving a pharmacologically active treatment.

30 Mar 2021

Microbiota-derived molecules do not change the entry or replication of SARS-CoV-2 in intestinal cells

A study conducted at the University of Campinas in the state of São Paulo, Brazil, shows that compounds produced by gut microbiota (bacteria and other microorganisms) during fermentation of insoluble fiber from dietary plant matter do not affect the ability of the novel coronavirus SARS-CoV-2 to enter and replicate in cells lining the intestines.

30 Mar 2021

Abdominal Pain News and Research

Further Reading

Direct action of SARS-CoV-2 on organs may lead to exacerbated inflammatory response in pediatric patients

Scientists explain possible causes of anaphylaxis following mRNA COVID-19 vaccination

Tens of thousands of women utilize the emergency department for fibroid symptoms

Mass screening reveals significantly higher numbers of coeliac disease cases in children

Loss of gut epithelial barrier responsible for COVID-19-related MIS-C in children, suggests study

Study shows how rare but serious post-COVID-19 complication develops in children, adolescents

Risk factors for rare COVID-19 complications in children (MIS-C)

Western diet impairs the gut immune system, could increase risk of inflammatory bowel disease

Investigational drug reduced triglycerides in patients with severe hypertriglyceridemia, acute pancreatitis

Guidance on diagnosis and management of cerebral venous sinus thrombosis after a COVID-19 vaccine

Study can help improve the clinical handling of giardiasis cases

Researchers aim to better understand clinical features associated with COVID-19 mortality

From rotten teeth to advanced cancer, patients feel the effects of treatment delays

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

GACVS COVID-19 reviews rare cases of blood clots following AstraZeneca COVID-19 vaccination

Study compares performance of open-label placebo to blinded placebo in IBS patients

Microbiota-derived molecules do not change the entry or replication of SARS-CoV-2 in intestinal cells

COVID-19 is more difficult to diagnose in children and adolescents, finds study

Mass immunization to stop Ebola outbreak in Guinea

FDA qualifies C-Path’s DIBSS-C for clinical trials

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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