Adenocarcinomas News and Research

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Scientists identify new target for developing novel drugs against several types of cancer

The Bcl-2 protein family comprises anti- and proapoptotic members, i.e. they protect the cell from death or favour it.

27 Oct 2020

Sortilin may hold the key to developing more effective treatment for pancreatic cancer

Pancreatic cancer has an extremely poor prognosis; it is the third most common cause of cancer deaths in the United States.

20 Aug 2020

Gum disease and esophageal and stomach cancer risk

American researchers have published their new findings on gum disease in a research letter in the latest issue of the journal Gut titled, "Periodontal disease, tooth loss, and risk of oesophageal and gastric adenocarcinoma: a prospective study."

20 Jul 2020

Quest Diagnostics Health Trends study: HPV screening less likely to detect cervical cancer than cotesting

A Health Trends study from researchers at Quest Diagnostics and the University of Pittsburgh Medical Center provides new evidence that the HPV screening test is significantly less likely to detect cervical cancer and precancer than cotesting, a method which combines HPV and Pap testing using the same specimen.

15 Jul 2020

Study suggests new potential strategy to fight against pancreatic cancer

A University of Michigan-led study is shedding new light on the way pancreatic cancer cells turn nearby connective tissue cells into co-conspirators in their deadly growth.

6 Jul 2020

UCI makes tremendous strides in prevention, early detection and treatment of cancer

Like most people, John Gifford wasn't looking forward to a colonoscopy when he arrived on the UCI Medical Center campus in Orange in 2018.

23 Feb 2020

Purdue-developed 'fluorescent markers' begin Phase 3 clinical trials

On Target Laboratories Inc., a privately held biotechnology company developing the use of Purdue University-discovered fluorescent markers to target and illuminate cancer during surgery, has announced the results of a multi-institutional Phase 2 clinical trial in which outcomes were improved for 26% of patients undergoing pulmonary resection for non-small-cell lung cancer.

6 Feb 2020

New technology enhances visualization of lung cancer tissue, helps improve patient outcomes

A groundbreaking tumor-highlighting technology- OTL38- enhances the visualization of lung cancer tissue, providing surgeons with a significantly better chance of finding and removing more cancer than previously possible, according to a scientific presentation at the 56th Annual Meeting of The Society of Thoracic Surgeons.

27 Jan 2020

RB1 alterations in cancer cells may lead to treatment resistance

The Cancer Genetics Group of the Josep Carreras Leukaemia Research Institute, led by Montse Sánchez-Céspedes, together with Luis Montuenga from CIMA, and Enriqueta Felip from Vall d'Hebron Hospital, has revealed that inactivation of RB1 through intragenic rearrangements is frequent in lung cancer cells from non-smoking patients with EGFR mutations.

24 Jan 2020

UChicago expert sheds light on pancreatic neuroendocrine tumors

Pancreatic cancer has been in the national spotlight lately with "Jeopardy" host Alex Trebek revealing his diagnosis. For the majority of all pancreatic cancer cases, the cancer begins in the ducts of the pancreas.

7 Jan 2020

GW researchers show connection between bacteria in the microbiome and colon cancer

A mutant protein found in humans with colon cancer blocks a pathway that regulates proliferation and expansion of cells, increasing amounts of bacterial species associated with the development of colon cancer.

4 Oct 2019

Combination therapies can shrink lung tumors in mice and human cancer cells

Combining a new class of drug with two other compounds can significantly shrink lung tumors in mice and human cancer cells, finds a new study led by the Francis Crick Institute and The Institute of Cancer Research, London.

17 Sep 2019

Distinctive characteristics in lung cancers could be key to personalized therapies

Melbourne researchers have discovered that the key to personalized therapies for some types of lung cancers may be to focus on their differences, not their similarities.

13 Sep 2019

New study helps explain why lung tumors turn aggressive

Lung cancer is the number 1 killer among cancers, especially when it is of the non-small cell type. Among these, adenocarcinomas are the most common and aggressive type. These tumors also show a strong tendency to show dedifferentiation, or loss of the features that characterize a mature lung cell.

28 Aug 2019

Discovery of distinct lung cancer pathways could help future patients

Known for its poor prognosis, lung adenocarcinoma is the most common type of lung cancer, responsible for about 4 of 10 diagnoses, according to the National Cancer Institute.

2 Aug 2019

MGH researchers identify potential markers of lung cancer

By examining both blood samples and tumor tissues from patients with non-small-cell lung cancer, investigators at Massachusetts General Hospital have identified markers that can distinguish between major subtypes of lung cancer and can accurately identify lung cancer stage.

16 Jul 2019

Early genome catastrophes can lead to development of lung cancer in non-smokers

Catastrophic rearrangements in the genome occurring as early as childhood and adolescence can lead to the development of lung cancer in later years in non-smokers.

31 May 2019

Cervical cancer subtype increasing in several subpopulations of women

A new study reports that a type of cervical cancer that is less amenable to Pap testing is increasing in several subpopulations of women, pointing to the growing importance of human papillomavirus (HPV) testing and vaccination.

17 Apr 2019

New analysis highlights increasing focus of early-stage clinical trials on rare cancers

The proportion of early-stage drug trials tackling the biggest cancer killers has declined sharply since the early 1990s as less common tumor types receive increasing attention, according to new research to be presented during the International Congress on Targeted Anticancer Therapies 2019, taking place from today to 27 February in Paris, France.

25 Feb 2019

New study finds how high-fat diets fuel colorectal cancer growth

As cancer death rates drop overall, doctors have noted a frightening anomaly: deaths from colorectal cancer in people under 55 appear to be creeping up. According to the American Cancer Society, deaths in this younger group increased by 1 percent between 2007 and 2016.

22 Feb 2019