Adenosine News and Research

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Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a ß-N9-glycosidic bond.

Wearables can identify changes in physiological systems during COVID-19 disease progression

If you become ill with COVID-19, your smartwatch can track the progression of your symptoms, and could even show how sick you become.

19 Apr 2022

The involvement of the skeletal muscles in long COVID-19

Researchers reviewed the mechanisms of muscle tissue injury, aggravating conditions, and associated sequelae in long COVID‐19.

18 Apr 2022

Scientists unravel the complex workings of the circadian rhythm in cyanobacteria

Scientists want to increase their understanding of circadian rhythms, those internal 24-hour biological clock cycles of sleeping and waking that occur in organisms, ranging from humans to plants to fungi to bacteria.

18 Apr 2022

COVID-19 may affect a group of biochemical reactions called one-carbon metabolism

A new study addresses the relationship between SARS-CoV-2 to the metabolism of one-carbon molecules in the host, suggesting new therapeutic pathways.

13 Apr 2022

Evidence SARS-CoV-2 undergoes ADAR-mediated A-to-I RNA editing in human cells

In a recent study published in the journal PLOS Genetics, researchers explored severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) ribonucleic acid (RNA) editing in host cells.

4 Apr 2022

Researchers show how an important inhibitor binds to the A2A receptor

The A2A receptor regulates how vigorously the innate immune system attacks diseased cells.

25 Mar 2022

Study: Targeting astrocytes reduces tau-related brain damage and inflammation in mice

Alzheimer's disease is the most common and best known of the tauopathies, a set of neurodegenerative brain diseases caused by toxic tangles of the protein tau.

18 Mar 2022

Narrative review reports two important mediators in SARS-CoV-2-induced ischemic stroke recovery

Researchers explored neuroinflammation and COVID-19-induced ischemic stroke recovery.

17 Mar 2022

Bioactive small molecules enhance CRISPR/Cas9 loss-of-function editing in human cells

Researchers demonstrate enhanced loss-of-function editing of CRISPR/Cas9 in human cells.

14 Mar 2022

Elevated P2X7 receptor levels in COVID-19 patients correlate with disease severity

In a recent study posted to the bioRxiv preprint server, researchers demonstrated that the soluble P2X7 receptor is increased in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients. They also showed that the elevated P2X7 receptors correlated with coronavirus disease 2019 (COVID-19) severity.

9 Mar 2022

Effect of COVID-19 mRNA vaccine on in vitro glial cells of the brain studied by Raman spectroscopy and imaging

Researchers studied how the mRNA-based BNT162b2 COVID-19 vaccine altered the biochemical composition of glial and glioma brain cells in vitro.

8 Mar 2022

Identification of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding

Researchers discovered compounds able to inhibit SARS-CoV-2 macrodomain 1 and adenosine diphosphate-ribose binding via high throughput screening.

7 Mar 2022

Diabetes and the mTOR pathway in COVID-19 patients

A new study discusses the possible etiopathogenetic mechanisms associated with diabetes that could enhance the severity of COVID-19.

6 Mar 2022

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

A new study describes the efficacy of adenosine receptor agonists in the treatment of SARS-CoV-2 infection.

2 Mar 2022

New prototype sensor aids in the rapid assessment of disease severity

Scientists have developed a prototype sensor that could help doctors rapidly measure adenosine triphosphate (ATP) and lactate levels in blood samples from patients, aiding in the rapid assessment of the severity of some diseases.

25 Feb 2022

Melatonin as a safe and potentially life-saving treatment for COVID-19

A new study discusses the possible role of melatonin, an antioxidant and anti-inflammatory agent, in treating COVID-19.

24 Feb 2022

Specialized subset of CD4+ T cells jump into action early during an infection, study shows

Every kind of T cell has a job to do. A healthy immune system makes sure no T cell oversteps.

22 Feb 2022

New insights could help long-term care facilities enhance infection prevention and control measures

Findings from a study published today in the American Journal of Infection Control provide new insights that could help long-term care facilities assess the cleanliness of high-touch surfaces, and thereby enhance infection prevention and control measures designed to prevent serious diarrheal diseases and deaths among their residents.

17 Feb 2022

How SARS-CoV-2 infection progresses throughout the respiratory system

Researchers discuss the progression of SARS-CoV-2 infection throughout the respiratory epithelium.

9 Feb 2022

Cocktail of two chemicals could help slow down age-related muscular decline

Researchers from Tokyo Metropolitan University have shown that a mixture of 5-aminolevulinic acid(5-ALA) hydrochloride and sodium ferrous citrate (SFC) helps slow down aging-related muscular decline in fruit flies, leading to a slower decline in locomotor activity and longer lifespans.

7 Feb 2022