Aging News and Research

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Study focuses on understanding how muscle fatigue and changes in gait affect older adults

Older adults on a walk or hike, or just going about their daily routines, seem to experience greater fatigue than their younger counterparts. Such fatigue may ultimately affect their ability to participate in activities that are meaningful to them and help keep them healthy.

25 Aug 2021

New discovery may lead to more effective treatments for osteoarthritis, other cartilage diseases

New information from a study reported on in STEM CELLS might result in more effective treatments for osteoarthritis and other cartilage diseases, as well as hereditary disorders affecting cartilage development.

25 Aug 2021

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

In the nearly 1 million Americans living with multiple sclerosis, the fatty substance that insulates the nerves of the central nervous system—called myelin—is damaged.

24 Aug 2021

New $14.5 million NIH grant to support research on HIV treatment and care in Central Africa

Researchers at Albert Einstein College of Medicine and the City University of New York Graduate School of Public Health and Health Policy have been awarded a five-year, $14.5 million grant from the National Institutes of Health to continue leading and expand their research on HIV treatment and care in five Central African nations.

24 Aug 2021

Pericentromeric noncoding RNA provokes inflammatory gene expression in senescence and cancer

Research from the Cancer Institute at the Japanese Foundation for Cancer Research (JFCR), which was published today (August 23, at 3 pm US ET) in the leading international scientific journal Proceedings of the National Academy of Sciences of the United States of America, reveals that noncoding RNA derived from pericentromeric repetitive sequences provokes inflammatory gene expression in senescence and cancer.

24 Aug 2021

Study shows higher risk of sarcopenia among older adults who are underweight and lack exercise

Analysis of medical data from around 1800 65-year-old residents of Kobe, a large Japanese city, has shown that at least 3% have possible sarcopenia (*1), revealing that the risks are higher in those who are underweight and don't exercise enough.

24 Aug 2021

Study identifies a novel potential biomarker for hepatocellular carcinoma

Aging-US published "Comprehensive analysis of the competing endogenous circRNA-lncRNA-miRNA-mRNA network and identification of a novel potential biomarker for hepatocellular carcinoma" which reported that there is still a lack of comprehensive analysis of the circular RNA -long non-coding RNA -miRNA-mRNA ceRNA network in hepatocellular carcinoma.

23 Aug 2021

Non-invasive retinal imaging may be useful for detecting Alzheimer's disease risk

Amyloid plaques are protein deposits that collect between brain cells, hindering function and eventually leading to neuronal death.

23 Aug 2021

Preclinical study validates crucial role of the spleen in cardiac repair

Although we can survive without a spleen, evidence continues to mount that this abdominal organ plays a more valuable role in our physiological defenses than previously suspected.

23 Aug 2021

Study investigates the effects of calycosin on breast cancer cell progression

Aging-US published "Calycosin inhibits breast cancer cell migration and invasion by suppressing EMT via BATF/TGF-β1" which reported that in this study, the authors investigated the effects of calycosin on breast cancer cell progression and their underlying mechanisms. Calycosin dose- and time-dependently inhibited proliferation, migration, and invasion by T47D and MCF-7 breast cancer cells by downregulating basic leucine zipper ATF-like transcription factor expression.

23 Aug 2021

Northwestern scientists discover remarkable longevity in a subset of mitochondrial proteins

Northwestern Medicine investigators have discovered that a subset of proteins in mitochondria of brain and heart cells are long-lived, supporting the long-term stability of mitochondrial complex architecture.

20 Aug 2021

After pandemic ravaged nursing homes, new state laws protect residents

When the coronavirus hit Martha Leland's Connecticut nursing home last year, she and dozens of other residents contracted the disease while the facility was on lockdown. Twenty-eight residents died, including her roommate.

20 Aug 2021

Biden’s no-jab-no-job order creates quandary for nursing homes

President Joe Biden's edict that nursing homes must ensure their workers are vaccinated against covid-19 presents a challenge for an industry struggling to entice its lowest-paid workers to get shots without driving them to seek employment elsewhere.

20 Aug 2021

Researchers identify genes associated with biochemical recurrence in prostate adenocarcinoma

Aging-US published "Identification of microenvironment related potential biomarkers of biochemical recurrence at 3 years after prostatectomy in prostate adenocarcinoma" which reported that the authors aimed to identify the potential prognostic genes in the prostate adenocarcinoma microenvironment and to estimate the causal effects simultaneously.

20 Aug 2021

Study: PirB inhibits the self-renewal and differentiation capacities of neural stem cells

Aging-US published "PirB functions as an intrinsic suppressor in hippocampal neural stem cells" which reported that neural stem cells play pivotal roles during prenatal development and throughout life.

20 Aug 2021

Research could enable clinicians to produce patient-matched cells for treating muscle-related diseases

Investigators who previously developed a recipe for turning skin cells into primitive muscle-like cells that can be maintained indefinitely in the lab without losing the potential to become mature muscle have now uncovered how this recipe works and what molecular changes it triggers within cells.

19 Aug 2021

Long-term circadian rhythm disruption induces Alzheimer's-like pathology in rats

Disrupted circadian rhythms, which can even be caused by chronic light exposure, affects normal physiological functions, resulting in anxiety, hyperactivity, and memory deficits.

19 Aug 2021

HMGA1 plays role in gastric cancer cell proliferation and metastasis

Aging-US published "HMGA1 promotes gastric cancer growth and metastasis by transactivating SUZ12 and CCDC43 expression" which reported that HMGA1 is overexpressed in GC cells and the high expression of HMGA1 was correlated with worse survival in GC patients using a bioinformatics assay.

19 Aug 2021

Two key brain functions may improve during aging

It's long been believed that advancing age leads to broad declines in our mental abilities. Now new research from Georgetown University Medical Center offers surprisingly good news by countering this view.

19 Aug 2021

Early COVID-19 vaccine campaign averted nearly 140,000 deaths in the U.S.

The early COVID-19 vaccination campaign in the U.S. prevented nearly 140,000 deaths and 3 million cases of COVID-19 by the second week of May, according to a new study.

18 Aug 2021

Aging News and Research

Study focuses on understanding how muscle fatigue and changes in gait affect older adults

New discovery may lead to more effective treatments for osteoarthritis, other cartilage diseases

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

New $14.5 million NIH grant to support research on HIV treatment and care in Central Africa

Pericentromeric noncoding RNA provokes inflammatory gene expression in senescence and cancer

Study shows higher risk of sarcopenia among older adults who are underweight and lack exercise

Study identifies a novel potential biomarker for hepatocellular carcinoma

Non-invasive retinal imaging may be useful for detecting Alzheimer's disease risk

Preclinical study validates crucial role of the spleen in cardiac repair

Study investigates the effects of calycosin on breast cancer cell progression

Northwestern scientists discover remarkable longevity in a subset of mitochondrial proteins

After pandemic ravaged nursing homes, new state laws protect residents

Biden’s no-jab-no-job order creates quandary for nursing homes

Researchers identify genes associated with biochemical recurrence in prostate adenocarcinoma

Study: PirB inhibits the self-renewal and differentiation capacities of neural stem cells

Research could enable clinicians to produce patient-matched cells for treating muscle-related diseases

Long-term circadian rhythm disruption induces Alzheimer's-like pathology in rats

HMGA1 plays role in gastric cancer cell proliferation and metastasis

Two key brain functions may improve during aging

Early COVID-19 vaccine campaign averted nearly 140,000 deaths in the U.S.

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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