Alcohol Dependence News and Research

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HTR3 variants associated with effectiveness of ondansetron treatment for alcohol dependence

An experimental treatment for alcohol dependence works better in individuals who possess specific combinations of genes that regulate the function and binding of serotonin, a brain chemical affected by the treatment, according to a study supported by the National Institutes of Health. A report of the finding appears online in the American Journal of Psychiatry.

3 Aug 2013

Study supports topiramate as promising medication to treat addiction

The drug topiramate, typically used to treat epilepsy and more recently weight loss, may also help people addicted to both cocaine and alcohol use less cocaine, particularly heavy users, researchers in the department of Psychiatry at Penn Medicine report in a new study published in Drug and Alcohol Dependence.

19 Jul 2013

Study reveals surprising patterns of racial disparities for successful drug treatment

A University of Iowa study reveals significant disparities between minority and white clients in success rates for completing substance abuse treatment programs. Moreover, these disparities vary widely from state to state.

20 Jun 2013

NIH awards $12.7M to research groups to explore new treatments for patients in eight disease areas

The National Institutes of Health has awarded $12.7 million to match nine academic research groups with a selection of pharmaceutical industry compounds to explore new treatments for patients in eight disease areas, including Alzheimer's disease, Duchenne muscular dystrophy and schizophrenia.

19 Jun 2013

Alkermes reports positive results from phase 1 study of ALKS 3831 for treatment of schizophrenia

Alkermes plc today presented positive results from a phase 1 study of ALKS 3831, a novel drug candidate for the treatment of schizophrenia, in an oral session at the 53rd Annual New Clinical Drug Evaluation Unit Meeting in Hollywood, Fla.

28 May 2013

Study examines effects of smoking on cognitive functioning in AD individuals

Treatment for alcohol use disorders works best if the patient actively understands and incorporates the interventions provided in the clinic.

18 May 2013

Bipolar disorder questionnaires limited for patients with SUD

Researchers advise caution when using the Mood Disorder Questionnaire and the Hypomania Checklist-32 to diagnose bipolar disorder in patients treated for substance use disorders.

25 Apr 2013

FDA agrees to allow ADial to move forward with Phase III trial of AD04 for alcohol use disorder

ADial Pharmaceuticals, LLC, announced today that the U.S. Food and Drug Administration has agreed to allow ADial to move forward with its plan to initiate Phase III trials of AD04 as a treatment for alcohol use disorder in certain targeted genotypes population only.

19 Apr 2013

Nalmefene can provide important clinical benefit for alcohol-dependent patients

A potential new treatment for alcoholism called nalmefene is effective and safe for reducing alcohol consumption in alcohol dependent individuals, says a new study published this week in Biological Psychiatry.

12 Apr 2013

Report: Nurses, midwives can play major role in improving health outcomes

Nurses and midwives can play a critical role in lessening people's risk of cardiovascular diseases, cancers, chronic respiratory disease and diabetes, according to a groundbreaking new report issued by the World Health Organization and co-authored by a UCLA nursing professor.

20 Mar 2013

Addiction risk increased after mild traumatic brain injury

A study of military personnel suggests that individuals who have suffered a mild traumatic brain injury are at increased for addiction-related disorders.

8 Mar 2013

Study determines frequency of genetic variants linked to alcoholism for Spanish population

Research done at the UPV/EHU-University of the Basque Country has determined the frequency of genetic variants linked to alcoholism for the Spanish population, and its incidence not only in individuals with a high level of alcohol intake, but also in individuals with alcohol dependence.

20 Feb 2013

Modafinil may help some people to reduce drinking by improving their impulse control

Poor impulse control contributes to one's inability to control the consumption of rewarding substances, like food, alcohol, and other drugs. This can lead to the development of addiction. FDA-approved medications for alcoholism, like naltrexone (Revia) and disulfiram (Antabuse), are thought to reduce alcohol consumption by curbing cravings and creating unpleasant reactions to alcohol, effects which reduce the desire to drink alcohol.

2 Feb 2013

Adolescents, alcohol and influences

Chances are the only thing you remember about your first swig of alcohol is how bad the stuff tasted. What you didn't know is the person who gave you that first drink and when you had it says a lot about your predisposition to imbibe later in life.

29 Jan 2013

Alcoholics Anonymous helps men and women maintain sobriety in different ways

A new study finds differences in the ways that participation in Alcoholics Anonymous (AA) helps men and women maintain sobriety. Two Massachusetts General Hospital (MGH) investigators found that, while many factors are helpful to all AA participants, some were stronger in men and some in women.

6 Dec 2012

University of Minnesota senior psychology fellow wins 2013 Grawemeyer Award

A mental health pioneer who explored the basis of schizophrenia and the way mental disorders are classified has won the 2013 University of Louisville Grawemeyer Award for Psychology.

28 Nov 2012

Twelve Step-based residential treatment benefits young adults with addiction

Young adults undergoing addiction treatment benefit from regular participation in Twelve Step-based self-help groups after discharge, according to a naturalistic study published electronically and in the journal Drug and Alcohol Dependence.

9 Nov 2012

Testosterone exposure early in life can have lasting impact on brain function and behavior

New findings led by Dr. Michael Lombardo, Prof. Simon Baron-Cohen and colleagues at the University of Cambridge indicate that testosterone levels early in fetal development influence later sensitivity of brain regions related to reward processing and affect an individual's susceptibility to engage in behavior, that in extremes, are related to several neuropsychiatric conditions that asymmetrically affect one sex more than the other.

6 Nov 2012

Most therapists still require abstinence for clients with substance dependence

Compared to a survey conducted nearly 20 years ago, about twice the proportion of addiction counselors now find it acceptable for at least some of their patients to have a drink occasionally - either as an intermediate goal or as their final treatment goal, according to a new study published by the American Psychological Association.

3 Nov 2012

Highlights from 25th European College of Neuropsychopharmacology Congress

In the course of the 25th ECNP Congress leading experts and five and a half thousand psychiatrists, neurologists, neuroscience researchers and public health professionals from over 90 different countries met from 13 to 17 October 2012 in Vienna, Austria, to celebrate ECNP´s 25-year anniversary and engage in groundbreaking debate.

26 Oct 2012