Amygdala News and Research

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Men's and women's brains behave differently

A key part of the brain involved in processing emotionally-influenced memories acts differently in men and women, even in the absence of stimuli, UC Irvine researchers have found.

11 Apr 2006

Functional magnetic resonance imaging can predict effectiveness of cognitive behavior therapy for treating depression

Whether or not cognitive behavior therapy (CBT) will help a person recover from depression can be predicted through brain imaging, according to research results published by the University of Pittsburgh School of Medicine in the April issue of the American Journal of Psychiatry.

4 Apr 2006

Gene linked to impulsive violence weakens brain circuits that regulate thinking in humans

A version of a gene previously linked to impulsive violence appears to weaken brain circuits that regulate impulses, emotional memory and thinking in humans, researchers at the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH) have found.

21 Mar 2006

New AF267B drug reverses key cognitive deficits, pathology in Alzheimer's

A new drug that enhances the activity of a key brain cell receptor involved in Alzheimer's disease (AD) reverses learning and memory deficits in mice engineered to have pathological hallmarks of the disease.

13 Mar 2006

How mammalian brains recognize other individuals

Imagine seeing a former high school classmate you always wanted to know better. Then imagine seeing that kid who used to push you in the hallways. Do you react differently? What happens in your brain during these encounters?

9 Mar 2006

Discovery of compound that reduces hallmark lesions of Alzheimer's disease in mice

Researchers at UC Irvine have found that a new compound not only relieves the cognitive symptoms of Alzheimer's disease, but also reduces the two types of brain lesions that are hallmarks of this devastating disease, thereby blocking its progression.

7 Mar 2006

Single memory is processed in three separate parts of the brain - important for search to understand memory disorders

UCI researchers have found that a single brief memory is actually processed differently in separate areas of the brain - an idea that until now scientists have only suspected to be true.

12 Feb 2006

Breakthrough in lupus research

A major breakthrough in lupus research - one that may fundamentally change thinking on how the disease affects behavior and cognition - was reported in the January 17, 2006 Proceedings of the National Academy of Sciences (PNAS).

25 Jan 2006

Bidirectional behavioral plasticity of memory reconsolidation depends on amygdalar protein kinase A

When activated, a specific protein in the brain enhances long-term storage of fearful memories and strengthens previously established fearful memories, Yale School of Medicine researchers report this week in Nature Neuroscience.

23 Jan 2006

Face perception is mediated by a distributed neural system in the human brain

New research indicates that an area of the brain thought to act in reward circuitry may represent a phase in visual processing during which sexual orientation modulates how we perceive individual faces. The findings are reported by Felicitas Kranz and Alumit Ishai of the University of Zurich.

11 Jan 2006

Brain volume may be used as an early detection system for dementia

Reduced volume, or atrophy, in parts of the brain known as the amygdala and hippocampus may predict which cognitively healthy elderly people will develop dementia over a six-year period, according to a study in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

2 Jan 2006

Long-term stress can impair short-term memory

Researchers believe that this occurs because constant stress affects an area of the brain necessary for learning and memory, and the underlying mechanisms for this may also be to blame in more serious ailments, such as post-traumatic stress disorder (PTSD) and severe depression.

15 Dec 2005

Surprising autism finding

New brain imaging research at the University of North Carolina at Chapel Hill indicates that when people with autism look at a face, activity in the brain area that responds is similar to that of people without autism.

13 Dec 2005

Amygdala activation to interpersonal threat can be specifically linked to the severity of social anxiety symptoms

People suffering generalised social phobia experience increased brain activity when confronted with threatening faces or frightening social situations, new research shows.

28 Nov 2005

Orbitofrontal thickness, retention of fear extinction, and extraversion

The relationship between the size of a brain structure and the ability to recover from traumatic experiences also may influence overall personality type, according to a study from Massachusetts General Hospital (MGH) researchers.

28 Nov 2005

Fear gene discovered

In the Nov. 18 issue of Cell, researchers report the discovery of a gene that controls the ability to react with appropriate fear to impending danger.

26 Nov 2005

Scientists discover gene which controls fear

Scientists have discovered the existence of a gene that appears to control whether fear reactions to impending danger are appropriate or not.

20 Nov 2005

New discovery helps explain complex neurocircuitry behind body weight control

A study led by a scientific team at Beth Israel Deaconess Medical Center (BIDMC) provides another important step in our understanding of the critical role that the brain's molecular pathways play in the development of obesity and related disorders.

7 Nov 2005

Search for genes responsible for anxiety disorders

Increasing the activity of two enzymes better known for their role in oxidative stress metabolism turns normally relaxed mice into "Nervous Nellies," according to research conducted at the Salk Institute for Biological Studies and reported in the early online edition of Nature.

30 Oct 2005

Link between emotional impairment and poor cognition in children with bipolar disorder

Using functional magnetic resonance imaging, Pavuluri and her colleagues examined the brain activity of teens while they were performing certain mental tasks. The researchers scanned the brains of 10 unmedicated bipolar patients with normal mood and compared them with 10 healthy subjects of the same age and gender.

20 Oct 2005