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UTHSC professor receives $455,000 grant to study cause of aggressive prostate cancer

Ramesh Narayanan, PhD, professor in the Department of Medicine and the Division of Hematology and Oncology at the University of Tennessee Health Science Center, has received a $455,000 grant from the National Cancer Institute for a two-year study of the underlying cause of the development of aggressive prostate cancer in African American men.

17 Sep 2020

Enzalutamide has added benefit for men with castration-resistant prostate cancer at high risk of metastasis

In 2018 and 2019, the German Institute for Quality and Efficiency in Health Care already investigated whether the drug enzalutamide has an advantage in comparison with the appropriate comparator therapy, i.e. in comparison with watchful waiting while maintaining ongoing conventional androgen deprivation therapy (ADT), for adult men with high-risk non-metastatic castration-resistant prostate cancer.

19 Aug 2020

Radiation therapy delay for prostate cancer patients offers room for flexibility during the pandemic

For cancer patients receiving radiation treatment during a surge in COVID-19 cases, adhering to the stay-at-home orders of quarantine is not always an option.

13 Aug 2020

Darolutamide shows indication of considerable added benefit in prostate cancer

Up to now, adult men with non-metastatic castration-resistant prostate cancer (nmCRPC) at high risk of developing metastatic disease usually continued their conventional androgen deprivation therapy (ADT) while the cancer was observed for the occurrence of metastases (so-called watchful waiting).

3 Aug 2020

Study shows moderate exercise reduces side effects of prostate cancer treatment

New research published this weekinExperimental Physiologyfound that in prostate cancer survivors,a moderate bout of exercise kept the cell count of certain type of immune cells at a normal level, suggesting the exercise is safe for prostate cancer survivors.

29 Jul 2020

Gene signature explains why 18F-FDG imaging performs better for PSMA-suppressed prostate cancer patients

Scientists have uncovered the genomic signature to explain why 18F-FDG imaging performs better than PSMA-targeted imaging for prostate cancer patients with low or no expression of the prostate-specific membrane antigen (PSMA).

23 Jul 2020

Investigational antidepressant PT150 shows antiviral activity against SARS-CoV-2

In a recent bioRxiv study, an ad hoc multi-institutional research team from the US shows that a novel hormone receptor modulator PT150 has unique and possibly additive antiviral and immunomodulatory effects – highlighting its potential role in the treatment and prophylaxis of coronavirus disease (COVID-19).

14 Jul 2020

New technique to sort out complex interactions unique to prostate cancer cells

UT Southwestern researchers have identified vast webs of small snippets of the genome that interact with each other and with genes to promote prostate cancer.

7 Jul 2020

Abnormal findings in testicular tissue of COVID-19 patients, SARS-CoV-2 mostly undetected

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused over 9.263 million cases and taken more than 477,000 lives as of June 24, 2020 – just six months after the initial outbreak in Wuhan, China, was reported. The illness, called COVID-19 disease, caused by SARS-CoV-2 is a severe pneumonic illness, caused by the entry of the virus into the type II alveolar cells.

24 Jun 2020

Clinical trial shows anti-tumor responses in metastatic castration-resistant prostate cancer patients

The preliminary results of a Phase I clinical trial conducted by researchers at the Yale Cancer Center have shown that ARV-110, an androgen receptor PROTAC protein degrader, demonstrates clinical evidence of anti-tumor responses in patients with metastatic castration-resistant prostate cancer (mCRPC) who have failed prior therapy.

29 May 2020

Multi-institutional clinical trial sheds new light on non-responsive tumors

Over the last decade, enzalutamide and similar drugs have led to significant tumor control and increased survival time for men who have metastatic prostate cancer that continues to grow despite treatments to reduce male hormone levels.

19 May 2020

Study provides insight into regenerative potential of prostate gland

The standard treatment for men with advanced prostate cancer is androgen-deprivation therapy. Androgens are hormones that fuel prostate cell growth; removing them with either drugs or surgery causes the prostate gland to shrink by 90%.

30 Apr 2020

Prostate cancer mortality rates predicted to fall in the EU but rise in Poland

Death rates from prostate cancer are predicted to fall in 2020 in the EU, largely due to better diagnosis and treatment, according to new research published in the leading cancer journal Annals of Oncology today (Monday).

20 Apr 2020

Death rates from prostate cancer predicted to decline overall in EU

Death rates from prostate cancer are predicted to fall in 2020 in the EU, largely due to better diagnosis and treatment.

17 Apr 2020

Mindful yoga may be a promising option for treating women with PCOS

Women with Polycystic Ovary Syndrome should consider adopting a mindful yoga practice to help ease symptoms and improve androgen levels. Researchers found a one-hour mindful yoga class, done three times a week, reduced testosterone levels by 29% over a three-month period.

14 Apr 2020

Mathematical model can predict patient outcomes to adaptive prostate cancer therapy

Prostate cancer is the most common malignancy among men in the United States. It is also the second most common cause of cancer-related deaths. Despite improved treatments for prostate cancer, many patients with advanced disease eventually develop drug resistance.

9 Apr 2020

Fracking chemical may interfere with reproductive hormones in men

A chemical used in hydraulic fracturing, commonly called fracking, has the potential to interfere with reproductive hormones in men, according to research accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.

31 Mar 2020

New viable therapeutic strategy found for ER+ breast cancer

Researchers say they have found a viable new therapeutic strategy for estrogen receptor-positive (ER+) breast cancer, even cancers that are resistant to current standard of care treatments.

31 Mar 2020

Potential new method of breast cancer treatment using androgen receptor

Scientists may have discovered a new therapeutic approach to treat ER+ breast cancer using androgen receptor-stimulating drugs.

31 Mar 2020

$Health concerns over fracking chemical that may cause adverse effects in male sex hormones$

Health concerns over fracking chemical that may cause adverse effects in male sex hormones

A study has found that fracking chemicals can interfere with male sex hormones and possibly cause adverse health effects.

31 Mar 2020

Androgen News and Research

UTHSC professor receives $455,000 grant to study cause of aggressive prostate cancer

Enzalutamide has added benefit for men with castration-resistant prostate cancer at high risk of metastasis

Radiation therapy delay for prostate cancer patients offers room for flexibility during the pandemic

Darolutamide shows indication of considerable added benefit in prostate cancer

Study shows moderate exercise reduces side effects of prostate cancer treatment

Gene signature explains why 18F-FDG imaging performs better for PSMA-suppressed prostate cancer patients

Investigational antidepressant PT150 shows antiviral activity against SARS-CoV-2

New technique to sort out complex interactions unique to prostate cancer cells

Abnormal findings in testicular tissue of COVID-19 patients, SARS-CoV-2 mostly undetected

Clinical trial shows anti-tumor responses in metastatic castration-resistant prostate cancer patients

Multi-institutional clinical trial sheds new light on non-responsive tumors

Study provides insight into regenerative potential of prostate gland

Prostate cancer mortality rates predicted to fall in the EU but rise in Poland

Death rates from prostate cancer predicted to decline overall in EU

Mindful yoga may be a promising option for treating women with PCOS

Mathematical model can predict patient outcomes to adaptive prostate cancer therapy

Fracking chemical may interfere with reproductive hormones in men

New viable therapeutic strategy found for ER+ breast cancer

Potential new method of breast cancer treatment using androgen receptor

Health concerns over fracking chemical that may cause adverse effects in male sex hormones

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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