Androgen News and Research

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New clinical trial focuses on quality of life for men with prostate cancer

A new Australian prostate cancer clinical trial hopes to provide clear evidence to men with prostate cancer about the best time to start hormone treatment in terms of prolonging life, balanced against the effects on their quality of life.

27 Apr 2005

Selenium will have critical role in prostate cancer treatment

Researchers at Fox Chase Cancer Center in Philadelphia have come a step closer to understanding selenium's molecular role in causing prostate cancer cells to self-destruct. According to data presented today at the 96th Annual Meeting of the American Association for Cancer Research in Anaheim, Calif., selenium helps malignant cells overcome their resistance to TRAIL-induced apopstosis (self-inflicted cell death).

20 Apr 2005

Breast cancer gene may play a major role in the recurrence of prostate cancer

A gene associated with breast cancer also may play a major role in the recurrence of prostate cancer, according to new research from the University of North Carolina at Chapel Hill School of Medicine and UNC Lineberger Comprehensive Cancer Center.

20 Apr 2005

Latest findings in male reproduction research

The XVIII North American Testis Workshop, chaired by Population Council senior scientist Matthew Hardy, will be held 30 March - 2 April in Seattle, Washington. Participants will discuss findings from the large body of recent research on male reproduction.

28 Mar 2005

Hormone therapy for prostate cancer can affect men's thinking

Androgen-deprivation therapy (AD), an effective therapy in the treatment of prostate cancer reduces levels of testosterone (a tumor stimulant), and estradiol, a form of estrogen, in men. These are known to be important in neurological development and play a particularly important role in the cognitive areas of learning and memory.

28 Feb 2005

Over-the-counter DHEA hormonal therapy may be an effective treatment for depression

The over-the-counter hormonal therapy known as DHEA may be an effective treatment of midlife-onset minor and major depression, according to a study in the February issue of The Archives of General Psychiatry. DHEA (dehydroepiandrosterone), an adrenal androgen and neurosteroid is available as a supplement in the U.S.

7 Feb 2005

Why some men develop aggressive prostate cancer that becomes resistant to hormone-withdrawal therapy

Researchers found that certain mutations in a protein called the androgen receptor cause advanced and invasive prostate cancer when put into otherwise healthy mice. The androgen receptor's normal function is to control growth of the prostate gland in response to cues from male hormones called androgens, which have long been thought to stimulate prostate tumors.

26 Jan 2005

Use of anti-inflammatory steroids for traumatic head injuries may actually increase the risk of death

The common use of anti-inflammatory steroids for traumatic head injuries like those from car crashes may actually increase the risk of death, according to a new review of studies about the treatment.

24 Jan 2005

Pancreatic beta-cells play an important role in the existence of polycystic ovary syndrome (PCOS)

Researchers have discovered that pancreatic beta-cells, which are responsible for insulin secretion, play an important role in the existence of polycystic ovary syndrome (PCOS), a hormonal disorder that affects up to 10 percent of reproductive aged women.

12 Jan 2005

Exposure to the chemical BPA (Bisphenol A) stimulates prostate cancer cell growth

An estrogen-like chemical commonly used to synthesize plastic food containers has been shown to encourage the growth of a specific category of prostate cancer cell, potentially affecting the treatment efficacy for a subset of prostate cancers.

4 Jan 2005

Polycystic ovary syndrome (PCOS), the most common endocrine disorder among reproductive-age women

The polycystic ovary syndrome (PCOS), the most common endocrine disorder among reproductive-age women, produces a wide variety of body changes with both physical and emotional implications for sufferers.

3 Jan 2005

Hirsute women most likely have androgen excess-related disorders, primarily polycystic ovary syndrome

Among women in their child-bearing years, even minimal amounts of unwanted hair in male-type patterns – especially in the presence of other subtle changes – may be a sign of a hormonal imbalance linked to a variety of serious side effects and medical conditions, according to the December 2004 issue of the American Journal of Obstetrics and Gynecology.

23 Dec 2004

Silent risk of osteoporosis in men with prostate cancer

Men being treated for prostate cancer using hormone therapy maybe under-recognized for their risk of developing osteoporosis, according to a new study.

13 Dec 2004

New surgical procedure enables men born with a very small penis to acquire an average-sized one

A surgical procedure being pioneered by University College London (UCL) urologists is enabling men born with a very small penis to acquire an average-sized, functioning penis which not only allows them to urinate normally, but for many, to enjoy a full sex life for the first time.

6 Dec 2004

Guidelines needed for the use of androgens for women with sexual dysfunction

The Endocrine Society, which represents more than 12,000 endocrinologists who are specially trained to diagnose, treat and conduct basic and clinical research on complex hormonal disorders, has called for new clinical guidelines on the use of androgens in women/female sexual dysfunction.

3 Dec 2004

Safe, effective and reversible alternative contraceptives for men

Most men know when their family is complete, and vasectomy remains the most effective and safest form of sterilization. Around 10% of vasectomized men in the U.S desire vasectomy reversal due to the high divorce rate in this country and other life circumstances.

16 Nov 2004

Testosterone may impede immunity

Decreasing testosterone boosts immunity because testosterone helps control T-lymphocytes, the attack cells of the immune system, according to Mayo Clinic-led research in laboratory animals.

8 Nov 2004

European approval for Taxotere (docetaxel) in prostate cancer

Aventis, part of the sanofi-aventis Group announced today that the European Commission has approved Taxotere (docetaxel) Injection Concentrate for use in combination with prednisone as a treatment for men with androgen-independent (hormone- refractory) metastatic prostate cancer.

4 Nov 2004

Men undergoing prostate cancer therapy forget things faster

Oregon Health & Science University researchers studying how testosterone deprivation affects verbal memory found that men undergoing the prostate cancer therapy forget things faster than their healthy counterparts.

25 Oct 2004

Paroxetine is an effective treatment for diminishing hot flashes in men who are receiving hormone therapy for prostate cancer

A new antidepressant medication is an effective treatment for diminishing hot flashes in men who are receiving hormone therapy for prostate cancer, Mayo Clinic researchers report in the October issue of Mayo Clinic Proceedings.

12 Oct 2004