Anencephaly News and Research

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Anencephaly is a condition in which a baby is born without most of a brain and skull. The brain may not be covered by bone or skin. Babies born with this condition do not survive more than a few hours or days. Anencephaly belongs to the group of disorders called neural tube defects.

Brain development takes an unexpected bend

Organs, such as the brain or the heart, are not simply collections of the correct types of cells that are required for their function. If these cells are not organized and shaped properly, the organ simply does not function. One crucial part of this organization is to bend sheets of connected cells ("epithelia") so that they form a structure that is an integral part of the functional organ.

4 Nov 2008

Low levels of dietary folate linked to sperm abnormalities

Healthy men who report lower levels of the nutrient folate in their diets have higher rates of chromosomal abnormalities in their sperm, according to a new study by researchers at the University of California, Berkeley, and the Lawrence Berkeley National Laboratory.

20 Mar 2008

Folic acid consumption before and during pregnancy

Taking a folic acid pill a day — a simple measure to prevent severe birth defects — is under-promoted in the media, under-recommended by health care providers and underused by women of childbearing age, according to a new review of studies.

6 Mar 2008

Study shows that folic acid added to flours lowers incidence of congenital neural tube deformation

Dr. Philippe De Wals of Universit' Laval's Department of Social and Preventive Medicine today publishes a study clearly indicating that the addition of folic acid to flours has led to a 46% drop in the incidence of congenital neural tube deformation (mainly anencephaly and spina bifida) in Canada. Such deformations either result in the child's death or in major health problems, including physical and learning disabilities.

13 Jul 2007

Impact of birth defects on families and nation

Two separate government reports highlight the economic costs of birth defects, focusing attention on the ongoing need for prevention.

22 Jan 2007

Survey highlights the need to increase folic acid fortification of the grain supply

Only one-third of childbearing age women are taking a multivitamin containing the B vitamin folic acid daily to prevent serious birth defects of the brain and spine in their future babies, according to a decade of March of Dimes surveys.

3 Oct 2005

Folic acid levels should be double to provide maximum protection during pregnancy

Reports say that the U.S. government decision to add folic acid to enriched grain products has reduced the incidence of two devastating birth defects. but more needs to be done.

6 Sep 2005

Folic acid fortification of grain foods has produced a one-third decline in serious birth defects of the brain and spine

...but the March of Dimes urged federal officials to help spare a greater number of babies from these devastating conditions by requiring higher levels of the B vitamin.

6 Sep 2005

Neural tube defects decrease with folic acid fortification

A new study published online April 21, 2005 in the American Journal of Medical Genetics Part A examines whether the recent decline in neural tube defects in Chile was due to the addition of folic acid to wheat flour in that country or to pre-existing decreasing trends. The journal is available online via Wiley InterScience.

21 Apr 2005

Brewing up potential anti-cancer drugs from green tea

Drinking green tea has a protective effect against some forms of cancer but drinking large amounts can increase the risk of birth defects such as spina bifida – according to previous epidemiological studies.

15 Mar 2005

Virginia Health urges women of childbearing age to take folic acid

According to data from a report released by the U.S. Centers for Disease Control and Prevention (CDC) in January 2004, only 35 percent of Virginia women of childbearing age take a vitamin pill that contains folic acid.

11 Jun 2004

Two serious birth defects in the U. S. are on the decline

Neural tube defects (NTDs) are serious birth defects of the spine (e.g., spina bifida) and the brain (e.g., anencephaly) that occur during early pregnancy, often before a woman knows she is pregnant.

10 May 2004

Spina bifida on the decline

The incidence of spina bifida has decreased by 32 percent in the United States over the past decade. The decrease indicates the success of the Public Health Service’s recommendations released in 1992 urging women to increase their levels of folic acid intake prior to becoming pregnant.

22 Mar 2004

Breast feeding increases choline which means more brain cells

Five years ago, University of North Carolina at Chapel Hill researchers first reported finding that the nutrient choline played a critical role in memory and brain function by positively affecting the brain’s physical development. Differences in development influenced action, the scientists and their colleagues found. In animal experiments conducted at Duke University, both young and old rats performed significantly better on memory tasks if they received enough choline before birth compared with same-age rats whose mothers were fed choline-deficient diets. The latter showed deficits in the hippocampus and septums of their brains.

22 Mar 2004