Angiotensin Converting Enzyme 2 News and Research

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Children's tonsils are major sites of prolonged SARS-CoV-2 infection

A recent study evaluates the presence of SARS-CoV-2 in children’s tonsils during the COVID-19 pandemic.

29 Jan 2023

Exploring an artificial neural network-based approach for detecting potentially infectious coronaviruses

Researchers used a machine-learning (ML)-based model to identify non-human CoVs (coronaviruses) that might cause human infections.

27 Jan 2023

Prenatal MRI helps visualize SARS-CoV-2 infection-induced abnormalities in the placenta and fetuses

Researchers performed a prospective case-control study on pregnant women with confirmed coronavirus disease 2019 (COVID-19).

26 Jan 2023

Study suggests cortical hemorrhage in fetal brain may be associated with COVID-19

Researchers evaluated the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on fetal brain health.

25 Jan 2023

Mosaic RBD nanoparticles offer 100% protection against SARS-CoV-2 in animal model

A recent PNAS journal study has sought to address the above-stated drawback and developed a new strategy that involves a self-assembling scaffold of proliferating cell nuclear antigen (PCNA). This technique can develop nanoparticles containing evenly incorporated heterotypic antigens.

24 Jan 2023

Researchers identify a key host-cell player in COVID-19 infections

Researchers at University of California San Diego and UC Riverside have further elucidated the molecular pathway used by the SARS-CoV-2 virus to infect human lung cells, identifying a key host-cell player that may prove a new and enduring therapeutic target for treating COVID-19.

24 Jan 2023

In silico study suggests SARS-CoV-2 Omicron XBB.1.5 strain to be more infective than previous strains

Researchers performed an in silico analysis to estimate the relative risks of recently emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants.

23 Jan 2023

What is the association between COVID-19, cardiovascular disease, and mortality?

In a new study, researchers evaluated the association between COVID-19 (coronavirus disease 2019) and CVD (cardiovascular disease) and/or death.

23 Jan 2023

Study suggests Alzheimer’s disease diagnosis is associated with higher levels of soluble ACE2 in the human brain

Researchers investigated ACE2 (angiotensin-converting enzyme 2) levels among individuals with AD (Alzheimer’s disease).

23 Jan 2023

Potent small-molecule inhibitors against SARS-CoV, MERS-CoV, and SARS-CoV-2

In a recent study posted to bioRxiv* preprint server, researchers in the United States identified several potent pan-coronavirus (CoV) inhibitors.

23 Jan 2023

SARS-CoV-2 Omicron XBB.1.5, CA.3.1, and CH.1.1 exhibit remarkable antibody resistance

In a recent study posted to bioRxiv* preprint server, researchers at Ohio State University examined the degree of neutralizing antibody (nAb) evasion by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron XBB.1.5, CA.3.1, and CH.1.1 subvariants.

23 Jan 2023

Longitudinal assessment of immunoglobulin G antibody responses to messenger ribonucleic acid vaccination doses and breakthrough infections

Researchers evaluated immunoglobulin G (IgG) responses to coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccinations.

20 Jan 2023

Exploring the infectivity, transmissibility, and immunological resistance characteristics of SARS-CoV-2 Omicron XBB.1.5 strain

Researchers performed an epidemic dynamic analysis to assess the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC)’s sub-VOC XBB.1.5 characteristics.

19 Jan 2023

How is long COVID diagnosed in adults?

In a recent study, researchers enlisted important points concerning post-coronavirus disease 2019 (COVID-19) or long COVID diagnosis among adults.

19 Jan 2023

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

Researchers explored the relationship between the development of goblet inflammatory cells and the age-related pathophysiology of SARS-CoV-2.

19 Jan 2023

How do mutations in emergent SARS-CoV-2 Omicron variants affect viral function, human immunity, and recognition by therapeutic antibodies?

Researchers explored how mutations in emergent SARS-CoV-2 variants affect viral function, human immunity, and recognition by therapeutic antibodies.

19 Jan 2023

Does COVID-19 cause adverse pregnancy and neonatal outcomes?

Early in the coronavirus disease 2019 (COVID-19) pandemic, pregnant women were thought to be at unusually high risk from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared to the general population or non-pregnant women. However, later studies failed to agree on the extent and nature of the danger posed by the infection.

18 Jan 2023

What are the major findings of long COVID research?

Researchers explored existing literature on long coronavirus disease (COVID). They highlighted key immunological findings, similarities with other diseases, symptoms, and associated pathophysiological mechanisms, and diagnostic and therapeutic options, including COVID-19 vaccinations.

17 Jan 2023

Exploring bioinformatics approach for evaluating binding affinities of probable COVID-19 therapeutic decoys

Researchers developed a computational workflow based on molecular dynamic (MD) simulations and artificial neural network (ANN) to assess the SARS-CoV-2 spike (S) protein receptor-binding domain (RBD)-human angiotensin-converting enzyme 2 (hACE2) binding affinities of SARS-CoV-2 variants.

17 Jan 2023

Preclinical study shows the therapeutic value of kinetin against SARS-CoV-2

Researchers investigated the ability of kinetin (N6-furfurylaminopurine, MB-905) to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proliferation in vitro.

17 Jan 2023

Angiotensin Converting Enzyme 2 News and Research

Children's tonsils are major sites of prolonged SARS-CoV-2 infection

Exploring an artificial neural network-based approach for detecting potentially infectious coronaviruses

Prenatal MRI helps visualize SARS-CoV-2 infection-induced abnormalities in the placenta and fetuses

Study suggests cortical hemorrhage in fetal brain may be associated with COVID-19

Mosaic RBD nanoparticles offer 100% protection against SARS-CoV-2 in animal model

Researchers identify a key host-cell player in COVID-19 infections

In silico study suggests SARS-CoV-2 Omicron XBB.1.5 strain to be more infective than previous strains

What is the association between COVID-19, cardiovascular disease, and mortality?

Study suggests Alzheimer’s disease diagnosis is associated with higher levels of soluble ACE2 in the human brain

Potent small-molecule inhibitors against SARS-CoV, MERS-CoV, and SARS-CoV-2

SARS-CoV-2 Omicron XBB.1.5, CA.3.1, and CH.1.1 exhibit remarkable antibody resistance

Longitudinal assessment of immunoglobulin G antibody responses to messenger ribonucleic acid vaccination doses and breakthrough infections

Exploring the infectivity, transmissibility, and immunological resistance characteristics of SARS-CoV-2 Omicron XBB.1.5 strain

How is long COVID diagnosed in adults?

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

How do mutations in emergent SARS-CoV-2 Omicron variants affect viral function, human immunity, and recognition by therapeutic antibodies?

Does COVID-19 cause adverse pregnancy and neonatal outcomes?

What are the major findings of long COVID research?

Exploring bioinformatics approach for evaluating binding affinities of probable COVID-19 therapeutic decoys

Preclinical study shows the therapeutic value of kinetin against SARS-CoV-2

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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