Antibiotic News and Research

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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.

Fidaxomicin demonstrates 45% reduction in recurrences vs. existing treatment for C. difficile infection

Clostridium difficile infection (CDI) is a significant and growing problem in hospitals and other health care facilities, but no new drugs to treat the condition have been developed in several decades. However, a large-scale, phase 3 trial conducted by Canadian and U.S. researchers shows that the new antibiotic Fidaxomicin is superior to existing treatments, demonstrating a 45 percent reduction in recurrences vs. the existing licensed treatment.

3 Feb 2011

Proper diagnosis and antibiotic treatment are the best way to prevent Lyme arthritis

Early, correct diagnosis is the best way to prevent the development of Lyme arthritis in individuals with the tick-borne illness, according to a paper published in the Journal of the American Academy of Orthopaedic Surgeons. In patients who do develop the condition, most cases can be treated successfully with antibiotics, the review found.

3 Feb 2011

Researchers discover potential vaccine capable of reducing H. pylori colonization

A new study led by researchers at Rhode Island Hospital in collaboration with the University of Rhode Island and EpiVax. Inc, a privately owned vaccine development company in Providence, RI, has identified a potential vaccine capable of reducing colonization of Helicobacter pylori -- a known cause of gastritis, ulcer disease and cancer.

2 Feb 2011

McLeod Health joins SafetyConnect to effectively monitor clinical data and reduce infections

By eliminating piles of paper, McLeod Health is now able to more effectively monitor clinical data and reduce infections with the help of the Premier healthcare alliance's SafetyConnect™ program.

1 Feb 2011

CINJ Foundation, Panera Bread enter joint venture to fight against cancer

Panera Bread has expanded its contributions to the fight against cancer by selecting the Cancer Institute of New Jersey Foundation as its Community Breadbox Partner for 2011.

1 Feb 2011

New research shows CEUS can improve diagnosis of variety of medical conditions in children

New research released here Thursday shows that "contrast-enhanced ultrasound" can safely improve the diagnosis of a variety of medical conditions in children - without exposing them to ionizing radiation.

29 Jan 2011

Antibiotic may help in development of new anti-cancer agents: Researchers

An antibiotic known for its immunosuppressive functions could also point the way to the development of new anti-cancer agents, researchers at the Indiana University School of Medicine have reported.

28 Jan 2011

USPTO issues Notice of Allowances to Lakewood's three patent applications for treatment of HUS

Lakewood-Amedex, a leading developer of novel anti-infective pharmaceuticals, announced today that the United States Patent and Trademark Office has issued Notice of Allowances on three patent applications relating to the use of novel monoclonal antibodies for the treatment of hemolytic uremic syndrome caused by shiga toxin II secreting E.coli O157: H7 strain.

28 Jan 2011

'Phenotype switching' helps bacteria lie dormant inside host cells and become a reservoir for relapsing infections

A new study into Staphylococcus aureus, the bacterium which is responsible for severe chronic infections worldwide, reveals how the bacteria have developed a strategy of hiding within host cells to escape the immune system as well as many antibacterial treatments. The research, published by EMBO Molecular Medicine, demonstrates how 'phenotype switching' enables bacteria to adapt to their environmental conditions, lie dormant inside host cells and become a reservoir for relapsing infections.

27 Jan 2011

Antibiotic use in first six months of life may result in childhood asthma

When babies are given antibiotics, their risk of developing asthma by age 6 may increase by 50 percent. This relationship between antibiotic use in babies less than six months old and risk of developing asthma was documented in a study conducted by Norwegian University of Science and Technology researcher Kari Risnes.

27 Jan 2011

MRSA screening in ICU patients can save costs for hospitals

Screening patients in the intensive care unit for methicillin-resistant Staphylococcus aureus roduces cost savings for the whole hospital, according to a study that used a statistical simulation model published in the February issue of the American Journal of Infection Control, the official publication of APIC - the Association for Professionals in Infection Control and Epidemiology.

27 Jan 2011

Research shows how pathogenic bacteria hide inside host cells

A new study into Staphylococcus aureus, the bacterium which is responsible for severe chronic infections worldwide, reveals how bacteria have developed a strategy of hiding within host cells to escape the immune system as well as many antibacterial treatments. The research, published by EMBO Molecular Medicine, demonstrates how ‘phenotype switching’ enables bacteria to adapt to their environmental conditions, lie dormant inside host cells and become a reservoir for relapsing infections.

26 Jan 2011

FDA accepts Optimer's fidaxomicin NDA for filing

Optimer Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has accepted for filing the Company's New Drug Application (NDA) for fidaxomicin for the treatment of Clostridium difficile infection (CDI) and for reducing the risk of recurrence when used for treatment of initial CDI.

24 Jan 2011

Mystery of 'inactive' defensin solved

Under standard laboratory conditions, the human beta-defensin 1 (hBD-1), a human antibiotic naturally produced in the body, had always shown only little activity against microbes. Nevertheless the human body produces it in remarkable quantities.

24 Jan 2011

Researchers discover nitroxoline can reduce human breast, bladder cancer cell growth

Researchers at the Johns Hopkins University School of Medicine have discovered that nitroxoline, an antibiotic commonly used around the world to treat urinary tract infections, can slow or stop the growth of human breast and bladder cancer cells by blocking the formation of new blood vessels.

20 Jan 2011

Legionnaires’ disease scare in Bali: Australian tourists warned

Commonwealth chief medical officer Jim Bishop has warned Australians who have returned from Bali on an outbreak of Legionnaires’ disease on the popular Indonesian resort island. The Australian health authorities knew of 11 cases of Legionnaires’ disease detected in Victorians and Western Australians after holidays in the Kuta area of Bali between August 2010 and January 2011.

19 Jan 2011

AMBR sensor measures growth and drug susceptibility of bacterial cells without use of microscope

With an invention that can be made from some of the same parts used in CD players, University of Michigan researchers have developed a way to measure the growth and drug susceptibility of individual bacterial cells without the use of a microscope.

19 Jan 2011

PROLOR and Yeda enter definitive license agreement for Reversible PEGylation technology

PROLOR Biotech, Inc., today announced that it has entered into a definitive license agreement with Yeda Research and Development Company Ltd. for novel technology utilized in the development of long-acting therapeutic peptides and small molecules, termed Reversible PEGylation.

18 Jan 2011

Vaccine to prevent MRSA infections after bone and joint surgery

University of Rochester Medical Center orthopaedic scientists are a step closer to developing a vaccine to prevent life-threatening methicillin-resistant staphylococcus aureus (MRSA) infections following bone and joint surgery.

18 Jan 2011

Antibiotics with blood pressure medications may cause hypotension

Mixing commonly used antibiotics with common blood pressure medications may cause hypotension and induce shock in older patients, requiring hospitalization, according to a study published in CMAJ.

18 Jan 2011

Antibiotic News and Research

Further Reading

Fidaxomicin demonstrates 45% reduction in recurrences vs. existing treatment for C. difficile infection

Proper diagnosis and antibiotic treatment are the best way to prevent Lyme arthritis

Researchers discover potential vaccine capable of reducing H. pylori colonization

McLeod Health joins SafetyConnect to effectively monitor clinical data and reduce infections

CINJ Foundation, Panera Bread enter joint venture to fight against cancer

New research shows CEUS can improve diagnosis of variety of medical conditions in children

Antibiotic may help in development of new anti-cancer agents: Researchers

USPTO issues Notice of Allowances to Lakewood's three patent applications for treatment of HUS

'Phenotype switching' helps bacteria lie dormant inside host cells and become a reservoir for relapsing infections

Antibiotic use in first six months of life may result in childhood asthma

MRSA screening in ICU patients can save costs for hospitals

Research shows how pathogenic bacteria hide inside host cells

FDA accepts Optimer's fidaxomicin NDA for filing

Mystery of 'inactive' defensin solved

Researchers discover nitroxoline can reduce human breast, bladder cancer cell growth

Legionnaires’ disease scare in Bali: Australian tourists warned

AMBR sensor measures growth and drug susceptibility of bacterial cells without use of microscope

PROLOR and Yeda enter definitive license agreement for Reversible PEGylation technology

Vaccine to prevent MRSA infections after bone and joint surgery

Antibiotics with blood pressure medications may cause hypotension

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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