Antibiotic News and Research

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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.

Importance of increased funding for molecular diagnostics

On July 9, 2009, the Society for Women’s Health Research convened experts on Capitol Hill to educate lawmakers on the importance of increased funding for new medical tests, called molecular diagnostics.

6 Aug 2009

Potential new antibiotics tested in pinhead-sized worms

In an advance that could help ease the antibiotic drought, scientists in Massachusetts are describing successful use of a test that enlists pinhead-sized worms in efforts to discover badly needed new antibiotics. Their study appeared in ACS Chemical Biology, a monthly journal.

6 Aug 2009

Aradigm receives orphan drug designation for inhaled liposomal ciprofloxacin to treat cystic fibrosis in Europe

Aradigm Corporation (OTCBB:ARDM) has announced that the European Medicines Agency (EMEA) granted Orphan Drug Designation to the Company’s inhaled liposomal ciprofloxacin drug product candidate for the treatment of lung infections associated with cystic fibrosis (“CF”).

6 Aug 2009

Research suggests that zinc activates a key protein on T cells needed to fight infections

Everyone knows that vitamins "from A to zinc" are important for good health. Now, a new research study in the August 2009 print issue of the Journal of Leukocyte Biology suggests that zinc may be pointing the way to new therapeutic targets for fighting infections.

31 Jul 2009

Delays could overwhelm hospitals in the event of airborne anthrax attack

A large attack on a major metropolitan area with airborne anthrax could affect more than a million people, necessitating their treatment with powerful antibiotics. A new study finds that in order for a response to be effective, quick detection and treatment are essential, and any delay beyond three days would overwhelm hospitals with critically ill people.

24 Jul 2009

Researchers expose the biology of Clostridium difficile transmission in mice

New research suggests that antibiotic treatment could be asymptomatically inducing the transmission of the healthcare-acquired infection, C. difficile, contributing to the outbreaks that have recently been widely reported in hospitals and other settings. A team of scientists have successfully mirrored the infection cycle of C. difficile by generating a 'mouse hospital' with conditions mimicking the human environment in which C. difficile is transmitted.

20 Jul 2009

Special pathway makes bacteria vulnerable - new target for tailored antibiotics

More and more strains of bacteria are developing resistance to previously life-saving antibiotics. Researchers at TUM, the Technische Universitaet Muenchen, have shed light on a metabolic step that appears in many aggressive microorganisms -- such as tuberculosis and malaria pathogens -- and that may provide a promising target for a new class of antibiotics. The researchers present their results in the chemistry journal Angewandte Chemie.

14 Jul 2009

The effects of antimicrobial therapy on bacterial vaginosis in non-pregnant women

Antimicrobial treatments for bacterial vaginosis (BV) are effective, but taking lactobacillus tablets alongside metronidazole antibiotic therapy increases effectiveness over taking this antibiotic alone, according to a Cochrane Systematic Review. The researchers also concluded that intravaginal lactobacillus was as effective as oral metronidazole, although they did note unexplained drop-outs from the trials.

7 Jul 2009

Whooping cough epidemic on North Coast of New South Wales

Health officials on the North Coast of New South Wales say there is now an epidemic of whooping cough in the region and they are advising young children and those who have close contact with them to be vaccinated.

5 Jul 2009

New UK national genome centre

A new UK national genome centre was officially opened by Nobel Laureate and genome pioneer Prof Sir John Sulston and the Lord-Lieutenant of Norfolk.

5 Jul 2009

Biological warfare in bacteria offers hope for new antibiotics

Scientists are to study a group of proteins that are highly effective at killing bacteria and which could hold the key to developing new types of antibiotics.

2 Jul 2009

Surgeons warn: Skateboarding tough on feet, ankles

Children and young adults love the thrill of skateboarding. They learn to master their skills of "riding the rail" and "catching air." But according to the American College of Foot and Ankle Surgeons (ACFAS), such tricks, while fun, can be physically demanding and cause serious foot and ankle injuries.

30 Jun 2009

Lancet Infectious Diseases examines spread of XDR-TB

The journal Lancet Infectious Diseases examines the worldwide spread of extensively drug-resistant tuberculosis (XDR-TB). Currently, about 500,000 of the 9 million new cases of TB that are identified each year are strains of XDR-TB. "Drug resistance is largely man-made - it is vitally important to review antibiotic treatment strategies and to ensure the Stop TB Strategy is fully applied to prevent further selection of drug-resistant mutants," Leonard Amaral of Universidade Nova de Lisboa said.

24 Jun 2009

Antibiotic prescribing should be standardized across Europe to help tackle resistance

Antibiotic prescribing for respiratory illnesses should be standardised across Europe to help reduce inappropriate prescribing and resistance, say experts in a study published on bmj.com.

24 Jun 2009

Forget swine flu - whooping cough far more of a worry!

Queensland Health authorities say there has been a surge in the number of whooping cough cases in far north Queensland - according to health officials there have been 205 cases of the disease in the state's far north already this year, seven times higher than the same time last year and Dr. Steven Donohue at the Tropical Population Health Service is warning parents to have their children immunised.

24 Jun 2009

Antibiotics diminish diversity of helpful gutmicrobes

It's common knowledge that a protective navy of bacteria normally floats in our intestinal tracts. Antibiotics at least temporarily disturb the normal balance. But it's unclear which antibiotics are the most disruptive, and if the full array of "good bacteria" return promptly or remain altered for some time.

18 Jun 2009

Honey more effective than antibiotics

In the first study of its kind University of Sydney researchers have found proof that some honeys can be more effective than antibiotics in treating surface wounds and infections.

17 Jun 2009

Preventing spread of infectious diseases is everyone’s responsibility – and everyone’s job

According to a report published today, we must all share responsibility for preventing the spread of diseases such as swine flu, SARS, avian influenza, diarrhoeal and skin diseases, and even the common cold.

16 Jun 2009

Plant microbe shares features with drug-resistant pathogen - implications for biotech

An international team of scientists has discovered extensive similarities between a strain of bacteria commonly associated with plants and one increasingly linked to opportunistic infections in hospital patients. The findings suggest caution in the use of the plant-associated strain for a range of biotech applications. The genetic analysis was conducted in part at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory, and will be published in the July 2009 issue of Nature Reviews Microbiology, now available online.

16 Jun 2009

High-tech approach to combat sepsis

When Jason Martin gives a talk about his research, he begins with the dramatic story of Mariana Bridi da Costa: The young Brazilian supermodel died from severe sepsis in January after amputation of both her hands and feet failed to stop its spread.

15 Jun 2009