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Recurrent SARS-CoV-2 positives not infectious in discharged COVID-19 patients, says Chinese study

A new research paper from China published on the preprint server medRxiv* claims that recurrent positive results for SARS-CoV-2 are due to the presence of low levels of viral RNA fragments and not the shedding of infectious virus particles.

29 Jul 2020

Exciting cost-effective SARS-CoV-2 vaccine candidate using Newcastle disease

Experts warn that the world may see repeated waves of the COVID-19 pandemic. However, scientists around the world are working hard to create a protective vaccine or antiviral, which could help to reduce the number of deaths and cases the next time around.

29 Jul 2020

Basigin/CD147 discarded as an accessory SARS-CoV-2 binding receptor

By using specialized assays customized to detect specific receptor interactions, researchers from the Wellcome Sanger Institute in Cambridge UK find no evidence for direct binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to a transmembrane glycoprotein known as basigin.

28 Jul 2020

Emergent SARS-CoV-2 D614G spike mutation more infective due to "open" morphology

Researchers from the Los Alamos National Laboratory and Duke Human Vaccine Institute & Department of Surgery demonstrated that globally prevalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with the amino acid substitution D614G in the spike protein is much more infective due to profitable binding encounters with the host receptors.

28 Jul 2020

Experimental vaccine rapidly controls coronavirus in the upper and lower airways of nonhuman primates

Two doses of an experimental vaccine to prevent coronavirus disease 2019 (COVID-19) induced robust immune responses and rapidly controlled the coronavirus in the upper and lower airways of rhesus macaques exposed to SARS-CoV-2, report scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. SARS-CoV-2 is the virus that causes COVID-19.

28 Jul 2020

Study identifies phosphorylation-based biomarkers to guide cancer therapy

Precision medicine in cancer treatment uses genetic changes in the cancer cells to select the best therapies for individual patients.

28 Jul 2020

Iron deficiency during infancy may reduce protective effect of vaccines

Despite the fact that global immunization programmes are now reaching more people than ever, about 1.5 million children still die every year from diseases that vaccination could have prevented. Vaccination is also less effective in low-income countries than in high-income countries, although it is not yet clear why.

28 Jul 2020

Pitt collaborative receives $7 million to evaluate convalescent plasma therapy for COVID-19

A team of University of Pittsburgh, Michigan Medicine, Medical University of South Carolina and Stanford Medicine. researchers recently were awarded funds from the National Heart, Lung, and Blood Institute in collaboration with the Biomedical Advanced Research and Development Authority, part of the Office of the Assistant Secretary for Preparedness and Response at the U.S. Department of Health and Human Services, totaling more than $7 million to collaboratively study the role of convalescent plasma in mitigating symptoms of COVID-19 in patients with mild illness and preventing the progression of the disease from mild to severe.

28 Jul 2020

UArizona aims to develop a device for quick and accurate detection of pathogens, biological threats

To better protect individuals serving on the front lines of battlefields or dealing with an event like the current COVID-19 health crisis or potential future pandemics, scientists at the University of Arizona College of Medicine - Phoenix are leading an effort to develop a device for easy, quick and accurate detection of pathogens and biological threats.

28 Jul 2020

Researchers identify practical way to induce strong and broad immunity to dengue virus

Researchers from Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, have found a practical way to induce a strong and broad immunity to the dengue virus based on proof-of-concept studies in mice.

28 Jul 2020

Ebola survivors have long-lasting severe immune dysfunction

In the 2013-2016 Ebola outbreak in West Africa, more than 28,000 people were infected, causing over 11,000 deaths.

27 Jul 2020

GW to participate in a clinical trial for investigational COVID-19 vaccine

The George Washington University today announced that it will participate in a clinical trial for an investigational COVID-19 vaccine.

27 Jul 2020

Novel label-free imaging method can differentiate active T cells from those off duty

T cells are the immune soldiers at the frontlines of the battle with infiltrating pathogens that seek to cause disease. A new study published in Nature Biomedical Engineering describes a novel label-free imaging technique that can differentiate active T cells from those off duty.

27 Jul 2020

Two-step targeting strategy can increase clinical translation of nanoparticle-based therapies

Therapy-loaded nanoparticles may be directed to the brain by functionalization with ligands targeting BBB-associated proteins.

27 Jul 2020

Scientists develop COVID-19 test to detect neutralizing antibodies with high sensitivity, specificity

According to a study published in Nature Biotechnology, the sVNT is capable of detecting the functional neutralizing antibodies (NAbs) that can block the binding of the coronavirus spike protein to the angiotensin-converting enzyme 2 (ACE2) host receptor, which mimics the virus-host interaction.

25 Jul 2020

National clinical trial to test potential vaccine against SARS-CoV-2

UC San Diego Health and the Altman Clinical and Translational Research Institute, part of UC San Diego School of Medicine, will be sites for an accelerated national clinical trial to assess the efficacy and immunogenicity of a vaccine intended to protect against SARS-CoV-2, the novel coronavirus that causes COVID-19.

25 Jul 2020

Higher levels of TGFBIp are correlated with severity of COVID-19 symptoms

A new study found raised levels of transforming growth factor beta-induced protein (TGFBIp) in blood sampled from roughly 100 people hospitalized for COVID-19, and further found that elevated levels of both the normal and acetylated forms of TGFBIp correlated with the severity of disease symptoms in these patients.

25 Jul 2020

South Texas Blood & Tissue Center marks three months of using Biolog-id's solution for COVID-19

Biolog-id, LLC, a world leader in connected solutions for blood products, and South Texas Blood & Tissue Center, a leading provider of blood products throughout South Texas and beyond, mark three months of successful utilization of Biolog-id’s dedicated Convalescent Plasma solution in its supply chain.

25 Jul 2020

MP Biomedicals and A*STAR jointly develop rapid antibody test kit for COVID-19

MP Biomedicals Asia Pacific Pte Ltd, a diagnostic corporation which has been operating for over 30 years focusing on various infectious disease testing development and manufacturing, today announced the successful development of a rapid antibody test kit for COVID-19, in collaboration with the Agency for Science, Technology and Research.

From MP Biomedicals, LLC 25 Jul 2020

Experimental mRNA-based COVID-19 vaccine elicits protective immune responses in animals

An experimental messenger RNA (mRNA)-based vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicits protective immune responses in mice and non-human primates, researchers report on July 23rd in the journal Cell.

24 Jul 2020

Antibodies News and Research

Recurrent SARS-CoV-2 positives not infectious in discharged COVID-19 patients, says Chinese study

Exciting cost-effective SARS-CoV-2 vaccine candidate using Newcastle disease

Basigin/CD147 discarded as an accessory SARS-CoV-2 binding receptor

Emergent SARS-CoV-2 D614G spike mutation more infective due to "open" morphology

Experimental vaccine rapidly controls coronavirus in the upper and lower airways of nonhuman primates

Study identifies phosphorylation-based biomarkers to guide cancer therapy

Iron deficiency during infancy may reduce protective effect of vaccines

Pitt collaborative receives $7 million to evaluate convalescent plasma therapy for COVID-19

UArizona aims to develop a device for quick and accurate detection of pathogens, biological threats

Researchers identify practical way to induce strong and broad immunity to dengue virus

Ebola survivors have long-lasting severe immune dysfunction

GW to participate in a clinical trial for investigational COVID-19 vaccine

Novel label-free imaging method can differentiate active T cells from those off duty

Two-step targeting strategy can increase clinical translation of nanoparticle-based therapies

Scientists develop COVID-19 test to detect neutralizing antibodies with high sensitivity, specificity

National clinical trial to test potential vaccine against SARS-CoV-2

Higher levels of TGFBIp are correlated with severity of COVID-19 symptoms

South Texas Blood & Tissue Center marks three months of using Biolog-id's solution for COVID-19

MP Biomedicals and A*STAR jointly develop rapid antibody test kit for COVID-19

Experimental mRNA-based COVID-19 vaccine elicits protective immune responses in animals

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