Antibodies News and Research

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Berkeley Lights Launches Cell Line Development 2.0 Workflow to Find Top Clones for Complex Antibody Therapeutics

The Opto™ Cell Line Development 2.0 workflow generates, in just days, the best production cell lines for complex antibody therapeutics.

From Bruker Cellular Analysis 10 Mar 2020

Gene therapy reverses cardiac dysfunction in mice with Barth syndrome

Barth syndrome is a rare metabolic disease in boys caused by mutation of a gene called tafazzin or TAZ. It can cause life-threatening heart failure and also weakens the skeletal muscles, undercuts the immune response, and impairs overall growth.

9 Mar 2020

Levels of sBTLA proteins may be a marker of overall survival in patients with HCC

In the 2020 February 25 issue of Scientific Reports, a research group from the Department of Hepatology in Osaka City University Graduate School of Medicine, Japan reported that levels of a circulating soluble immune checkpoint protein can be used as a potential marker to predict overall survival in patients with advanced HCC.

9 Mar 2020

Gut bacteria can boost effectiveness of cancer immunotherapy, mice study suggests

Could the response to cancer immunotherapy depend on bacteria that originate in the gut and travel to the tumor?

7 Mar 2020

Sphingotec’s bio-ADM can reliably support physicians in identifying high-risk sepsis patients

Diagnostics company SphingoTec GmbH today reported on new data on the utility of endothelial function biomarker bioactive Adrenomedullin

5 Mar 2020

Respiratory antivirals and risk to breastfeeding women

Little data is available about the ability of antiviral drugs used to treat COVID-19, coronavirus, to enter breastmilk, let alone the potential adverse effects on breastfeeding infants.

4 Mar 2020

How do cells protect themselves from viruses?

Amid the coronavirus outbreak that is wreaking havoc across the globe, it is essential to know how the cells of the body evade infection from viruses. A team of scientists has explained the mechanism that takes place in case a virus penetrates the body.

4 Mar 2020

Asthma and COPD can increase risk of rheumatoid arthritis

Asthma and chronic obstructive pulmonary disease (COPD) were each associated with increased risk for developing rheumatoid arthritis in a study published in Arthritis & Rheumatology.

4 Mar 2020

Patients with rheumatoid arthritis more likely to quit smoking, shows study

Smoking doubles the risk of developing rheumatoid arthritis and continuing to smoke after being diagnosed has negative effects on patients.

4 Mar 2020

The changing face of the COVID-19 epidemic

The SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) virus, which hit China with the disease now named COVID-19 in December 2019 and has since spread to over 70 countries, has caused over 90,000 cases, and 3,117 fatalities, with 95% or more of both being in China.

2 Mar 2020

Clinical factors during pregnancy associated with congenital CMV infection in newborns

A group led by researchers from Kobe University has illuminated clinical factors that are related to the occurrence of congenital cytomegalovirus infection in newborns.

28 Feb 2020

Researchers elucidate structure and function of enzyme that builds complex sugar trees

Researchers have used cryo-electron microscopy to elucidate for the first time the structure and function of a very small enzyme embedded in cell membranes.

27 Feb 2020

Bifunctional nanobodies with antitoxin potencies could protect against botulinum neurotoxins

New study reveals potential for developing novel antibody-based antitoxins against botulinum neurotoxins (BoNTs), including the most commonly used, yet most toxic one, Botox.

27 Feb 2020

Advanced hollow nanomaterials can be used to create biosensors for early cancer detection

For the first time, a team of scientists at the University of Central Florida has created functional nanomaterials with hollow interiors that can be used to create highly sensitive biosensors for early cancer detection.

26 Feb 2020

Aggressive cancers set up a structural framework to keep the immune system at bay

Aggressive colorectal cancers set up an interactive network of checkpoints to keep the immune system at bay, scientists report.

26 Feb 2020

Autoantibodies can also act as the body's own antidepressants

If the immune system attacks its own body, it can often have devastating consequences: autoantibodies bind to the body's structures, triggering functional disorders.

24 Feb 2020

Guiding nanoparticles directly to the tumor cells

Modern anticancer therapies aim to attack tumor cells while sparing healthy tissue. An interdisciplinary team of researchers at Helmholtz-Zentrum Dresden-Rossendorf and FU Berlin has made important progress in this area: the scientists have produced tiny nanoparticles that are designed to specifically target cancer cells.

24 Feb 2020

Scientific breakthrough provides insights into basic mechanisms of allergic reactions

An international research team has been able to describe the overall structure of the antibody type IgE, which is the key molecule in allergic diseases.

24 Feb 2020

Simple blood test could be used by GPs to aid in earlier brain tumor diagnosis

A new simple blood test for brain tumors that could be used by GPs in primary care is being developed thanks to funding of nearly £500,000 by Cancer Research UK.

24 Feb 2020

A step towards precision medicine for the management of monogenic diabetes

Diabetes affects more than 400 million people worldwide and is a major public health problem. Although commonly referred to as a single disease, it actually constitutes a group of metabolic disorders with hyperglycemia as a common feature. Of all its forms, monogenic diabetes - due to a mutation in one of the genes involved in the management of blood sugar levels - affects 1% to 4% of all cases of diabetes.

22 Feb 2020

Antibodies News and Research

Berkeley Lights Launches Cell Line Development 2.0 Workflow to Find Top Clones for Complex Antibody Therapeutics

Gene therapy reverses cardiac dysfunction in mice with Barth syndrome

Levels of sBTLA proteins may be a marker of overall survival in patients with HCC

Gut bacteria can boost effectiveness of cancer immunotherapy, mice study suggests

Sphingotec’s bio-ADM can reliably support physicians in identifying high-risk sepsis patients

Respiratory antivirals and risk to breastfeeding women

How do cells protect themselves from viruses?

Asthma and COPD can increase risk of rheumatoid arthritis

Patients with rheumatoid arthritis more likely to quit smoking, shows study

The changing face of the COVID-19 epidemic

Clinical factors during pregnancy associated with congenital CMV infection in newborns

Researchers elucidate structure and function of enzyme that builds complex sugar trees

Bifunctional nanobodies with antitoxin potencies could protect against botulinum neurotoxins

Advanced hollow nanomaterials can be used to create biosensors for early cancer detection

Aggressive cancers set up a structural framework to keep the immune system at bay

Autoantibodies can also act as the body's own antidepressants

Guiding nanoparticles directly to the tumor cells

Scientific breakthrough provides insights into basic mechanisms of allergic reactions

Simple blood test could be used by GPs to aid in earlier brain tumor diagnosis

A step towards precision medicine for the management of monogenic diabetes

Immunology eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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