Antibodies News and Research

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Location location location, even for genes

Moving an active gene from the interior of the nucleus to its periphery can inactivate that gene report scientists from the University of Chicago Medical Center in an article to be published early online Feb.13, 2008, in the journal Nature.

14 Feb 2008

Some cases of autism may be traced to the immune system of mothers during pregnancy

New research from the UC Davis M.I.N.D. Institute and Center for Children's Environmental Health has found that antibodies in the blood of mothers of children with autism bind to fetal brain cells, potentially interrupting healthy brain development.

12 Feb 2008

Prenatal exposure to maternal antibodies linked to autistic behaviors in offspring

New research from the UC Davis M.I.N.D. Institute shows that an interaction between fetal brain cells and maternal antibodies could be linked with the repetitive behavior - also called stereotypies - that is characteristic of autism.

12 Feb 2008

Gene therapy protocol at UCSD activates immune system in patients with leukemia

A research team at the Moores Cancer Center at University of California, San Diego (UCSD) reports that patients with chronic lymphocytic leukemia (CLL) who were treated with a gene therapy protocol began making antibodies that reacted against their own leukemia cells.

12 Feb 2008

Molecules developed at UB boost vaccine potency

Two novel proteins studied by a University at Buffalo professor of microbiology and immunology appear to have the potential to enhance the production of antibodies against a multitude of infectious agents.

5 Feb 2008

New vaccine for malaria under trial

Trials are underway, funded by the Wellcome Trust, for a new vaccine to combat the most deadly form of malaria.

5 Feb 2008

New discoveries on what does and doesn't affect immune system

Scientists know that a number of factors can affect the body's immune system: poor diet, certain steroids, chronic stress. Now researchers at Michigan State University have discovered that an appetite-controlling hormone also affects the immune system, while natural versions of certain steroids do not.

4 Feb 2008

Researchers uncover key interaction in cholesterol regulation

Researchers at UT Southwestern Medical Center have determined the specific way in which a destructive protein binds to and interferes with a molecule that removes low-density lipoproteins (LDL), the so-called "bad" cholesterol, from the blood.

4 Feb 2008

A possible H5N1 vaccine

A vaccine against the most common and deadliest strain of avian flu, H5N1, has been engineered and tested by researchers at the University of Pittsburgh's Center for Vaccine Research and Novavax Inc.

4 Feb 2008

Study looks at safe dosages of the isotope astatine-211 for brain tumors

In a study to determine safe dosages of the isotope astatine-211 for patients with recurring brain tumors, researchers were pleasantly surprised to find that not only was the isotope's potency sufficient to kill residual cancer cells without damaging sensitive healthy brain cells, but the patients experienced longer survival rates.

4 Feb 2008

Breakdown of kidney's self-cleaning ability makes them more vulnerable to dysfunction and disease

The kidney actively cleans its most selective filter to keep it from clogging with blood proteins, scientists from Washington University School of Medicine in St. Louis reveal in a new study.

30 Jan 2008

New nanomedicine research for prostate cancer

The Prostate Cancer Foundation, largely through the generosity of David H. Koch, has given $5 million to four institutions, including Weill Cornell Medical College, to support novel research in prostate cancer. The gift is one of the largest-ever individual donations for prostate cancer research.

29 Jan 2008

Candidate malaria vaccine shows promise

A small clinical trial conducted by an international team of researchers in Mali has found that a candidate malaria vaccine was safe and elicited strong immune responses in the 40 Malian adults who received it.

24 Jan 2008

Genmab reaches milestones in Ofatumumab collaboration

The second milestone payment of the collaboration of DKK 87.2 million was triggered by treatment of the first patient in the Phase II study of ofatumumab in Diffuse Large B-Cell Lymphoma (DLBCL), which occurred in 2007.

22 Jan 2008

A new significance of LVD and angiogenic MVD is identified in human primary SCRC

Lymphangiogenesis and angiogenesis are critical processes for tumor growth, invasion and metastasis.

17 Jan 2008

Gold nanoparticles shine brightly in tumors

Solid gold nanoparticles have long been used to treat rheumatoid arthritis and more recently have shown promise in treating various types of cancer.

16 Jan 2008

Cancer cell targeting using multiple aptamers conjugated on nanorods

Aptamers, short stretches of DNA or RNA that can act much like antibodies, have shown promise as targeting agents for selective nanoparticle trafficking to tumors.

16 Jan 2008

Uncovering the Achilles' heel of the HIV-1 envelope

New structural details illustrate how a promising class of antibodies may block human immunodeficiency virus (HIV)-1 infection and reveal valuable clues for design of an effective HIV-1 vaccine.

15 Jan 2008

A few more pieces for the puzzle that is Alzheimer’s disease

Alzheimer's disease (AD) affects as much as 10% of the world population above 65 years of age but after years of research it is still not understood exactly how the disease appears and, even less, how to treat it.

11 Jan 2008

Morphotek announces agreement for development of antibodies to treat prostate cancer

Morphotek, Inc., a subsidiary of Eisai Co., Ltd., has announced that it has signed a Cooperative Research and Development Agreement (CRADA) with the National Cancer Institute (NCI) for the development of therapeutic antibodies to a cancer-associated protein identified by NCI researchers.

10 Jan 2008