Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Home test using paper strips could help detect cancer, malaria

What if testing yourself for cancer or other diseases were as easy as testing your blood sugar or taking a home pregnancy test? In a few years, it might be.

29 Jun 2016

Two vaccine candidates provide complete protection against ZIKV infection in mice

The rapid development of a safe and effective vaccine to prevent the Zika virus (ZIKV) is a global priority, as infection in pregnant women has been shown to lead to fetal microcephaly and other major birth defects.

29 Jun 2016

Deficiency in NMD could cause inflammatory myofibroblastic tumors

Inflammatory myofibroblastic tumors (IMTs) — masses of immune cells— are benign, but poorly understood. Current IMT treatments often have side effects and surgery is sometimes not an option due to the tumor's proximity to vital organs.

28 Jun 2016

Scientists isolate antibodies capable of neutralizing dengue and Zika virus

Scientists from the Institut Pasteur and the CNRS, in collaboration with Imperial College London and the University of Vienna, Austria, have identified antibodies that can efficiently neutralize both the dengue virus and the Zika virus.

24 Jun 2016

Pre-existing dengue antibodies can intensify Zika virus infection

Previous exposure to the dengue virus may increase the potency of Zika infection, according to research from Imperial College London.

23 Jun 2016

Scientists streamline total synthesis of uncialamycin drug

A team led by Rice University scientists has improved the production of a potent anti-tumor antibiotic known as uncialamycin.

23 Jun 2016

'Simple' model predicts PegIFN response in chronic HBV

Chinese researchers have developed a scoring system based on hepatitis B virus-related clinical parameters to predict response to pegylated-interferon in chronic HBV patients.

23 Jun 2016

Switch to rituximab shows anti-inflammatory effect in relapsing-remitting MS

Rituximab may be an attractive treatment option for patients with relapsing-remitting multiple sclerosis, suggest phase II study findings showing its efficacy in controlling inflammatory activity.

22 Jun 2016

Salvage inotuzumab ozogamicin improves ALL outcomes

Compared with standard chemotherapy, treatment with inotuzumab ozogamicin increases the rate of complete remission and allows a higher proportion of patients with relapsed or refractory acute lymphoblastic leukaemia to subsequently receive stem-cell transplantation, research suggests.

22 Jun 2016

Researchers seek to develop novel antibody to treat glioblastoma

Scientists of Helmholtz Zentrum München and the Munich University Hospital are developing a novel antibody to treat brain tumors.

22 Jun 2016

New CAR-based therapy using combined cancer target could be effective for solid tumors

Chimeric antigen receptors (CARs), engineered from a patient's own immune cells, have been successful for treating blood cancers, but using CARs for solid tumors has been limited by side effects to normal tissues containing the protein targeted by the engineered cells.

22 Jun 2016

Researchers aim to improve medical treatment for people with insect venom allergy

A team of researchers has elucidated individual profiles of allergy reactivity in patients that are not protected after treatment with immunotherapy. The aim is to improve medical treatment of people who are allergic to insect stings.

21 Jun 2016

Rice University researchers synthesize new anti-cancer agent

Rice University scientists have synthesized a novel anti-cancer agent, Thailanstatin A, which was originally isolated from a bacterial species collected in Thailand.

20 Jun 2016

People with higher levels of IgG/IgM antibodies less likely to have heart attack

Measuring antibody levels in the blood could be used to detect a person's heart attack risk after researchers, part-funded by the British Heart Foundation, discovered that higher levels of these antibodies are linked to a lower heart attack risk.

20 Jun 2016

S1P1R variation may cause differential patient responses to fingolimod treatment

Multiple sclerosis (MS) is an autoimmune disorder that results in demyelination of neurons. The FDA-approved drug fingolimod (Gilenya, FTY-720) modulates signaling by the bioactive lipid sphingosine-1-phosphate (S1P), which is linked to MS pathogenesis.

16 Jun 2016

New FcMBL-based pathogen-detecting assay could rapidly detect systemic infections

To date, there are no methods that can quickly and accurately detect pathogens in blood to allow the diagnosis of systemic bloodstream infections that can lead to life-threatening sepsis.

15 Jun 2016

T memory cells with naive phenotype can help boost immunity in older adults

Sixty-five is the age when many people retire, kick back and take it easy. And so it often is with the human immune system.

14 Jun 2016

Nearly half of newly-infected HIV patients experience neurologic issues

A team led by researchers from UCSF and Yale has found that half of people newly infected with HIV experience neurologic issues. These neurologic findings are generally not severe and usually resolve after participants started anti-retroviral therapy.

14 Jun 2016

Novel radioimmunotherapy may help cure colorectal cancer

An emerging cancer therapy has colorectal tumors surrounded. Presenters at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging are unveiling a novel radioimmunotherapy that combines a cancer-seeking antibody with potent radionuclide agents, resulting in complete remission of colorectal cancer in mouse models.

14 Jun 2016

Postnova reports advances in analysis of plasma proteins using AF4-ICP-MS system

Postnova Analytics reports on exciting advances in the analysis of plasma proteins using a hyphenated system that couples asymmetric flow Field-Flow Fractionation (AF4) and inductively coupled plasma-mass spectrometry.

From Postnova Analytics 13 Jun 2016