Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Second potential immune checkpoint target for cancer immunotherapy announced by Compugen

Compugen Ltd. (NASDAQ: CGEN) announced today results demonstrating the therapeutic potential of CGEN-15022, a Compugen-discovered B7/CD28-like membrane protein, as an immune checkpoint target for treatment of multiple cancers.

27 Jun 2012

Having antibodies for cutaneous HPV and sun exposure can act synergistically in BCC, SCC

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and the German Cancer Research Center in Heidelberg have found that having antibodies for cutaneous types of human papillomavirus (HPV), coupled with sun exposure (ultraviolet radiation) or poor tanning ability, can act "synergistically" in the development of non-melanoma skin cancers such as basal cell carcinoma (BCC) and squamous cell carcinoma (SCC).

26 Jun 2012

KaloBios’ KB001 shows promise against Pa pneumonia

Phase 2a trial results with KB001 suggest the recombinant, human PEGylated monoclonal antibody fragment, under development by KaloBios Pharmaceuticals, Inc. and Sanofi Pasteur, offers potential as an alternative to antibiotics for preventing or reducing pneumonias in mechanically ventilated intensive care unit (ICU) patients heavily colonized with Pseudomonas aeruginosa (Pa).

26 Jun 2012

Merck Serono, Compugen announce establishment of Neviah Genomics

Merck Serono, a division of Merck, Darmstadt, Germany, and Compugen Ltd. today announced the establishment of Neviah Genomics, a novel start-up company focused on the discovery and development of novel biomarkers for the prediction of drug-induced toxicity.

26 Jun 2012

Genentech's Perjeta helps people with HER2-positive metastatic breast cancer live longer

Genentech, a member of the Roche Group, announced today that people with HER2-positive metastatic breast cancer (mBC) lived significantly longer (overall survival) when treated with the combination of Perjeta (pertuzumab), Herceptin (trastuzumab) and docetaxel chemotherapy, compared to Herceptin and docetaxel chemotherapy alone in the Phase III CLEOPATRA study.

23 Jun 2012

AbGenomics raises $11 million in current financing round

AbGenomics International announced today that it has raised $11 million in current financing round. It brings total investment in AbGenomics to approximately $52 million since its inception in 2000.

23 Jun 2012

Longer looks: Alzheimer's researcher turns to drug she helped invent

Given her relatively young age, Dr. Rae Lyn Burke didn't think much about her family history of Alzheimer's disease -- a grandmother and an aunt had suffered from it, but they were much older. Ironically, Burke was just in her late 50s when she started having her own symptoms of early onset Alzheimer's. Even more ironic is that Burke had been one of the key developers of the Alzheimer's drug bapineuzumab, which she now takes herself to reduce the progression of the disease in her own brain.

22 Jun 2012

FDA approves CDC DENV-1-4 Real Time RT PCR Assay to treat dengue

The Centers for Disease Control and Prevention has developed a new diagnostic test to detect the presence of dengue virus in people with symptoms of dengue fever or dengue hemorrhagic fever. The test, called the CDC DENV-1-4 Real Time RT PCR Assay, has been authorized by the Food and Drug Administration for use in the United States and can be performed using equipment and supplies many public health laboratories already use to diagnose influenza.

21 Jun 2012

RayBiotech, Institute for Cancer Research collaborate to implement antibody-based sample analysis

RayBiotech, Inc. and the combined genotyping core facility for Oslo University Hospital and the University of Oslo, located at the Institute for Cancer Research, announced the execution of an agreement to collaborate for the implementation of antibody-based sample analysis services.

19 Jun 2012

SDIX advanced Genomic Antibody Technology to be highlighted at BIO International Convention

SDIX today announced that it will be showcasing progress with its advanced Genomic Antibody Technology data package this week's BIO International Convention, one of the largest global partnering events for the biotechnology industry.

19 Jun 2012

Allergy risk in children linked to antibacterials in personal-care products

Exposure to common antibacterial chemicals found in soap, toothpaste, mouthwash and other personal-care products may make children more prone to a wide range of food and environmental allergies, according to new research from Johns Hopkins Children’s Center.

19 Jun 2012

Single-dose vaccine for treatment of cocaine addiction

A single-dose vaccine capable of providing immunity against the effects of cocaine offers a novel and groundbreaking strategy for treating cocaine addiction is described in an article published Instant Online in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc.

19 Jun 2012

New clinical data for ZEVALIN Injection for intravenous use presented at 17th EHA Congress

Spectrum Pharmaceuticals, Inc., a biotechnology company with fully integrated commercial and drug development operations with a primary focus in oncology and hematology, today announced new clinical data presented in an oral presentation for ZEVALIN (ibritumomab tiuxetan) Injection for intravenous use at the 17th Congress of the European Hematology Association (EHA).

19 Jun 2012

iBio expands iBioModulator portfolio with allowance of patent for anthrax vaccines

iBio, Inc. today announced that the US Patent Office has allowed patent application 11/706,576 entitled "Bacillus anthracis Antigens, Vaccine Compositions, and Related Methods."

19 Jun 2012

Novel strategy for neutralizing unwanted molecules and clearing them from the body

Researchers have unveiled a novel strategy for neutralizing unwanted molecules and clearing them from the body.

18 Jun 2012

BEAMing DNA blood testing technology detects drug resistance in colorectal cancer patients early

Two studies published back-to-back in last week's Nature applied DNA blood testing using the BEAMing technology to detect drug resistance mediated by KRAS mutations in colorectal cancer patients months before treatment failure was observed.

18 Jun 2012

Ambrx, Merck collaborate to develop and commercialize biotherapeutic drug conjugates

Ambrx today announced that the company has entered into a collaboration with Merck to design and develop rationally optimized biologic drug conjugates based on Ambrx's site-specific protein medicinal chemistry technology.

18 Jun 2012

Impressive results from blinatumomab Phase 2 study on B-precursor ALL

At the 17th Congress of the European Hematology Association in Amsterdam Professor Max Topp of the University of Wuerzberg in Germany presents the impressive results with a bispecific antibody for Acute Lymphoblastic Leukemia patients.

18 Jun 2012

SQI raises CDN $754,000 in third and final tranche of private placement

SQI Diagnostics Inc., a life sciences company that develops and commercializes proprietary technologies and products for advanced microarray diagnostics, announced today it has raised gross proceeds of CDN $754,000 from the closing of the third and final tranche of a non-brokered private placement of 430,713 units priced at $1.75 per Unit.

15 Jun 2012

Theraclone Sciences commences TCN-202 Phase 1 trial in CMV infection

Theraclone Sciences, Inc., a therapeutic antibody discovery and development company, announced today first dosing of subjects in a Phase 1 clinical trial of TCN-202, a broadly protective, fully human monoclonal antibody in development for the treatment of human cytomegalovirus (CMV) infection.

15 Jun 2012

Antibody News and Research

Further Reading

Second potential immune checkpoint target for cancer immunotherapy announced by Compugen

Having antibodies for cutaneous HPV and sun exposure can act synergistically in BCC, SCC

KaloBios’ KB001 shows promise against Pa pneumonia

Merck Serono, Compugen announce establishment of Neviah Genomics

Genentech's Perjeta helps people with HER2-positive metastatic breast cancer live longer

AbGenomics raises $11 million in current financing round

Longer looks: Alzheimer's researcher turns to drug she helped invent

FDA approves CDC DENV-1-4 Real Time RT PCR Assay to treat dengue

RayBiotech, Institute for Cancer Research collaborate to implement antibody-based sample analysis

SDIX advanced Genomic Antibody Technology to be highlighted at BIO International Convention

Allergy risk in children linked to antibacterials in personal-care products

Single-dose vaccine for treatment of cocaine addiction

New clinical data for ZEVALIN Injection for intravenous use presented at 17th EHA Congress

iBio expands iBioModulator portfolio with allowance of patent for anthrax vaccines

Novel strategy for neutralizing unwanted molecules and clearing them from the body

BEAMing DNA blood testing technology detects drug resistance in colorectal cancer patients early

Ambrx, Merck collaborate to develop and commercialize biotherapeutic drug conjugates

Impressive results from blinatumomab Phase 2 study on B-precursor ALL

SQI raises CDN $754,000 in third and final tranche of private placement

Theraclone Sciences commences TCN-202 Phase 1 trial in CMV infection

Antibodies eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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