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Researchers discover mechanism that plays key role in development of resistance to immunotherapy

In tumor immunotherapy, the body's own defense system is activated against the tumor cells. However, for the majority of patients, the tumor cells become resistant to the treatments used.

25 Jul 2017

Diagnosing prostate cancer through a £225 urine test

This test, which we have branded SelectMDx for Prostate Cancer, came with the acquisition of a company in the Netherlands called NovioGendix. They developed a prototype assay, so they did most of the heavy lifting in terms of discovering the two specific biomarkers that are currently in the product. These biomarkers are tuned towards the detection of what I call clinically significant prostate cancer.

24 Jul 2017

High dose flu vaccine reduces risk of respiratory and all-cause hospitalizations, study finds

In the largest nursing home study to date on the effect of a high dose (HD) flu vaccine, researchers found that vaccines with four times the antigen of standard flu (SD) vaccines significantly reduced the risk of respiratory and all-cause hospitalization during flu season.

21 Jul 2017

Cow immunization may lead to new human vaccines and treatments for HIV, study finds

Antibodies against the Human Immunodeficiency Virus (HIV) have been obtained for the first time by injecting cows with an HIV antigen. This achievement offers promise for the development of anti-HIV treatments or vaccines.

21 Jul 2017

Researchers find new way to protect stem cells from inflammation during wound repair

Scientists have found a new way to protect stem cells from harsh inflammation during wound repair. In a study recently published in the journal Cytotherapy, researchers in India discovered that treating mice with a common anti-inflammatory drug called celecoxib promoted stem cell survival and healing when they injected the cells into wounds.

20 Jul 2017

Skin-applied microneedle patch boosts immunization to seasonal flu vaccine recipients, study finds

A boosting skin vaccination with a biodegradable microneedle patch and protein constructed from sequences of influenza virus subtypes could improve the effectiveness of conventional influenza vaccines, according to a study led by Georgia State University.

19 Jul 2017

Scientists uncover new genetic markers that predispose individuals to lupus

Scientists from an international consortium have identified a large number of new genetic markers that predispose individuals to lupus.

18 Jul 2017

Cord-blood-derived natural killer cells can be modified to destroy B-cell cancers

Immune cells with a general knack for recognizing and killing many types of infected or abnormal cells also can be engineered to hunt down cells with specific targets on them to treat cancer, researchers at The University of Texas MD Anderson Cancer Center report in the journal Leukemia.

13 Jul 2017

Surgery may not prolong life in men with early-stage prostate cancer

A major 20-year study provides further evidence that prostate cancer surgery offers negligible benefits to many men with early-stage disease.

13 Jul 2017

JAX researchers explore how dendritic cells promote adaptive immunity to virus

A research team led by Jackson Laboratory Professor Karolina Palucka, M.D., Ph.D., in collaboration with a research team at Institut Curie in France led by Dr. Nicolas Manel, have addressed a long-standing puzzle of immunology: How do dendritic cells (DCs) do their job of promoting adaptive immunity to a virus while avoiding getting infected themselves?

7 Jul 2017

Study: Personalized neoantigen vaccine stimulates strong anti-tumor response in melanoma patients

A personal cancer treatment vaccine that targets distinctive "neoantigens" on tumor cells has been shown to stimulate a potent, safe, and highly specific immune anti-tumor response in melanoma patients, report scientists from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

5 Jul 2017

Researchers discover protein that makes stem cells into perfect allrounders

Researchers from the University of Zurich and the University Hospital Zurich have discovered the protein that enables natural embryonic stem cells to form all body cells.

28 Jun 2017

Scientists use supercomputers to test new techniques for early cancer detection

An important factor in fighting cancer is the speed at which the disease can be identified, diagnosed and treated.

28 Jun 2017

Discovery of T cell exhaustion offers new pathway to more powerful immunotherapies

St. Jude Children's Research Hospital immunologists have discovered how immune cells called T cells become "exhausted" -- unable to do their jobs of attacking invaders such as cancer cells or viruses.

28 Jun 2017

Two-test combination accurately identifies benign pancreatic lesions

When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely benign.

23 Jun 2017

Scientists develop new algorithm to decipher how immune system recognizes and binds antigens

Scientists from St. Jude Children's Research Hospital and Fred Hutchinson Cancer Research Center have developed an algorithm that functions like a Rosetta Stone to help decipher how the immune system recognizes and binds antigens.

22 Jun 2017

Simple blood test could improve treatment for many stage 2 colon cancer patients

A simple blood test could improve treatment for more than 1 in 6 stage 2 colon cancer patients, suggests new Mayo Clinic research. The researchers also discovered that many patients who could benefit from the test likely aren't receiving it.

21 Jun 2017

Study emphasizes importance of molecule in maintaining balanced immune system in the gut

A healthy gut requires a molecule called gp96 to train the immune system to tolerate food and normal microbes, report researchers at the Medical University of South Carolina in the May 19, 2017 issue of Scientific Reports.

14 Jun 2017

Researchers use quantum dots to decipher design features for new therapies aimed at MS

Researchers in the University of Maryland Fischell Department of Bioengineering (BIOE) Jewell Laboratory are using quantum dots - tiny semiconductor particles commonly used in nanotechnology - to decipher the features needed to design specific and effective therapies for multiple sclerosis (MS) and other autoimmune diseases.

14 Jun 2017

Antibody-based theranostic agent shows promise for identifying and treating pancreatic tumors

Pancreatic cancer is associated with bleak five-year survival rates and limited treatment options, but new research is offering hope.

13 Jun 2017

Antigen News and Research

Researchers discover mechanism that plays key role in development of resistance to immunotherapy

Diagnosing prostate cancer through a £225 urine test

High dose flu vaccine reduces risk of respiratory and all-cause hospitalizations, study finds

Cow immunization may lead to new human vaccines and treatments for HIV, study finds

Researchers find new way to protect stem cells from inflammation during wound repair

Skin-applied microneedle patch boosts immunization to seasonal flu vaccine recipients, study finds

Scientists uncover new genetic markers that predispose individuals to lupus

Cord-blood-derived natural killer cells can be modified to destroy B-cell cancers

Surgery may not prolong life in men with early-stage prostate cancer

JAX researchers explore how dendritic cells promote adaptive immunity to virus

Study: Personalized neoantigen vaccine stimulates strong anti-tumor response in melanoma patients

Researchers discover protein that makes stem cells into perfect allrounders

Scientists use supercomputers to test new techniques for early cancer detection

Discovery of T cell exhaustion offers new pathway to more powerful immunotherapies

Two-test combination accurately identifies benign pancreatic lesions

Scientists develop new algorithm to decipher how immune system recognizes and binds antigens

Simple blood test could improve treatment for many stage 2 colon cancer patients

Study emphasizes importance of molecule in maintaining balanced immune system in the gut

Researchers use quantum dots to decipher design features for new therapies aimed at MS

Antibody-based theranostic agent shows promise for identifying and treating pancreatic tumors

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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