Antihypertensive Drug News and Research

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New target found for asthma

An enzyme released by mast cells in the lungs appears to play a key role in the tightening of airways that is a hallmark of asthma -- pointing to a potential new target for treatment against the illness.

29 Jan 2008

Evidence strongly supports diuretics as initial metabolic syndrome therapy, especially in black patients

New research shows that in people with high blood pressure as part of metabolic syndrome, a cluster of conditions that increases the risk for heart disease, diuretics offer greater protection against cardiovascular disease, including heart failure, and are at least as effective for lowering blood pressure as newer, more expensive medications.

28 Jan 2008

Gene variations associated with effectiveness of blood pressure medications

Patients with hypertension and certain gene variations experienced varying results with some blood pressure medications, suggesting matching a patient's genotype with certain hypertension medications could result in more favorable outcomes, according to a study in the January 23 issue of JAMA: The Journal of the American Medical Association.

23 Jan 2008

Telmisartan potent against stroke

Telmisartan, a drug widely used to help control blood pressure, may have uniquely potent activity in preventing stroke, according to a new study conducted in an animal model.

13 Dec 2007

Some drug studies more likely to have favorable conclusions

Previous work has shown that, when a drug study was funded by the company that made that drug, the results might be biased in favour of that drug because the methods or analyses were manipulated.

19 Nov 2007

Fenofibrate intervention and event lowering in diabetes

Fenofibrate is the first and only widely available lipid modifying agent to demonstrate significant protection to the eye of patients with type 2 diabetes, reducing the need for laser therapy in a wide spectrum of patients which should decrease the risk of progressive loss of vision.

6 Nov 2007

More effective method of treating high blood pressure

Scientists at Robarts Research Institute have developed a simplified and more effective method of treating high blood pressure.

6 Nov 2007

Elderly with hypertension less likely to get lifestyle modification advice from doctors

People older than 60 with high blood pressure are less likely than other groups of patients to receive advice from their doctors about lifestyle modifications that can help lower their blood pressure, a study by UNC researchers concludes.

5 Nov 2007

Valsartan might help prevent Alzheimer's disease

Alzheimer disease (AD), a neurodegenerative disease that is the most common form of dementia, is characterized by the formation in the brain of plaques containing misfolded beta-amyloid protein.

25 Oct 2007

Severely mentally ill at high risk for cardiovascular disease

A psychiatrist at Washington University School of Medicine in St. Louis writes in the Journal of the American Medical Association (JAMA) that although mortality from cardiovascular disease has declined in the United States over the past several decades, patients with severe psychiatric illness are not enjoying the benefits of that progress.

17 Oct 2007

Memory tasks require more coordinated brain blood flow for people with high blood pressure

Blood flow to the parts of the brain that support memory function differs between people with high blood pressure and those with normal blood pressure, and this difference seems to increase when high blood pressure is treated with medications, researchers reported today at the American Heart Association's 61st Annual Fall Conference of the Council for High Blood Pressure Research.

27 Sep 2007

Hispanics' hypertension better controlled with equal access to care

With equal access to medical care and medication, Hispanic men and women have as good or greater chance as non-Hispanics of controlling their high blood pressure, researchers reported in Hypertension: Journal of the American Heart Association.

13 Sep 2007

Gene-drug interactions that lower blood pressure

Patients with high blood pressure respond very differently to antihypertensive medication, making treatment selection tricky for physicians.

13 Sep 2007

Pocket guidelines for assessment and management of cardiovascular risk

A new book of pocket-charts that will help health workers to identify people at risk of heart attacks and strokes and save lives by prescribing the most appropriate treatment is published today by the World Health Organization (WHO). The charts can be adapted for use in any setting, in any country, with any patient.

12 Sep 2007

Sleep deprived women at risk of heart disease

British researchers have found that women who deprive themselves of sleep may be more likely to die of heart disease.

11 Sep 2007

Women more at risk from sleep deprivation than men

New research led by researchers at Warwick Medical School at the University of Warwick reveals that women's health is much more at risk from sleep deprivation than men's.

10 Sep 2007

Hypertension in the very elderly trial stopped

An international trial looking at the benefits of giving blood-pressure lowering medication to elderly patients has stopped early, after researchers observed significant reductions in overall mortality in those receiving treatment.

7 Aug 2007

Ranbaxy receives approval to manufacture and market Amlodipine Besylate tablets

Ranbaxy Pharmaceuticals Inc. (RPI), a wholly owned subsidiary of Ranbaxy Laboratories Limited (RLL), has announced that RLL has received final approval from the U.S. Food and Drug Administration to manufacture and market Amlodipine Besylate Tablets, 2.5 mg (base), 5 mg (base) and 10 mg (base).

11 Jul 2007

Drug costs cut in Norway following new rule on prescribing

Research in Norway has shown that there have been substantial savings in drug costs since the introduction of a regulation requiring doctors to prescribe the recommended first-line treatment for hypertension (high blood pressure).

9 Jul 2007

Ranbaxy receives tentative approval to manufacture Amlodipine Besylate tablets

Ranbaxy Pharmaceuticals Inc. (RPI), a wholly owned subsidiary of Ranbaxy Laboratories Limited (RLL), announced that RLL has received tentative approval from the U.S. Food and Drug Administration to manufacture and market Amlodipine Besylate Tablets, 2.5 mg (base), 5 mg (base) and 10 mg (base).

23 Jun 2007