Apixaban News and Research

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Newer anticoagulant may be safer for dialysis patients with Afib

People with irregular heartbeat due to a condition called atrial fibrillation, are often prescribed blood thinners to reduce the risk of blood clots that can cause a stroke.

30 Jun 2018

Anticoagulant drugs found safe to use in patients undergoing surgery for irregular heartbeat

A trial led by the University of Birmingham has found that two types of blood thinning drugs are safe to use in patients with an irregular heartbeat when they are undergoing surgery aimed at stopping the condition.

21 Mar 2018

Study: Non-vitamin K antagonist oral anticoagulants linked to reduced kidney risks

Mayo Clinic researchers have shown a link between which type of oral anticoagulant (blood-thinning medication) a patient takes to prevent a stroke and increased risks of kidney function decline or failure.

20 Nov 2017

Study: 1 in 6 patients on new blood-thinning medications may not be receiving recommended dose

Almost 1 in 6 of the millions of Americans on the new blood-thinning medications for atrial fibrillation, a common heart condition characterized by an irregular and often rapid heart rate, may not be receiving the recommended dose, new Mayo Clinic research finds.

5 Jun 2017

Therapeutic small molecules safely prevent blood clots without excessive bleeding

It may be possible to disrupt harmful blood clots in people at risk for heart attack or stroke without increasing their risk of bleeding, according to a new study published in Nature Communications.

31 May 2017

Delayed anticoagulation treatment for atrial fibrillation patients increases dementia risk, study finds

A new study has found that dementia rates increase when anticoagulation treatment is delayed for patients with atrial fibrillation, the most common heart arrhythmia in the world that affects more than 2.7 million American adults.

12 May 2017

Low dose of alternative anticoagulant may help prevent stroke in hemodialysis patients

New research suggests that an alternative to warfarin, when given at a low dose to dialysis patients, can be maintained in the blood at safe levels for potentially preventing strokes.

17 Mar 2017

Researchers develop portable sensor for fast, accurate assessment of blood's clotting ability

Case Western Reserve University researchers have developed a portable sensor that can assess the clotting ability of a person's blood 95 times faster than current methods—using only a single drop of blood.

4 Dec 2016

Study provides insight into available treatments for stroke prevention in atrial fibrillation patients

A recent study from University of Alabama at Birmingham researchers published in PLOS ONE compares different available treatments for stroke prevention in patients with non-valvular atrial fibrillation.

26 Oct 2016

Novel antidote effective in quickly reversing acute anticoagulant-related bleeding

A specially designed antidote to reverse acute, potentially life-threatening anticoagulant-related bleeding worked quickly, and was well-tolerated according to interim results of the ongoing ANNEXA-4 study.

30 Aug 2016

New oral anticoagulants offer same stroke prevention, but cause less intracranial bleeding than warfarin

The new oral anticoagulants provide the same stroke prevention as warfarin but cause less intracranial bleeding, reports an observational study in more than 43 000 patients presented at ESC Congress 2016 today by Dr Laila Staerk, a research fellow at Herlev and Gentofte University Hospital, Denmark.

28 Aug 2016

NOACs match warfarin for atrial fibrillation

Real-world study data from Denmark show that non-vitamin K antagonist oral anticoagulants are effective alternatives to warfarin in patients with non-valvular atrial fibrillation in a routine care setting.

23 Jun 2016

Apixaban effective in polypharmacy setting

The superiority of apixaban over warfarin in patients with atrial fibrillation is maintained in those taking multiple medications, shows further analysis of the ARISTOTLE trial.

21 Jun 2016

Worsening renal function linked to increased cardiovascular risk in AF

Patients with atrial fibrillation and declining renal function are at increased risk of subsequent stroke or systemic embolism, major bleeding and death, US researchers report.

17 Jun 2016

New oral blood thinners can decrease stroke risk in atrial fibrillation patients without frequent monitoring

A new generation of blood thinners can reduce the risk of stroke in patients with atrial fibrillation, without requiring frequent monitoring and dietary restrictions.

16 Apr 2016

Primary care physicians often under- or over-estimate stroke and bleeding risk in AF patients

Patients with atrial fibrillation (AF) have an increased risk for stroke and are often prescribed oral anticoagulation (OAC) therapy. OAC therapy can prevent disastrous strokes, but at the expense of increased bleeding risks. There are now well-established guidelines to assess the risk of stroke and bleeding in AF patients to determine whether OAC is needed.

19 Oct 2015

Educational program does not influence patients’ adherence to apixaban anticoagulant

Adherence to the oral anticoagulant apixaban among patients with atrial fibrillation (AF) was no better for those who received an educational program compared to those who did not, results of the international, randomised AEGEAN trial show.

31 Aug 2015

Normal coagulation tests used to check for side effect of internal bleeding may not be reliable

A recently-published study found that while internal bleeding may be uncommon as a result of taking blood thinners such as Xarelto (rivaroxaban) and Eliquis (apixaban), the normal coagulation tests physicians use to check for the side effect of bleeding may not be reliable.

24 Aug 2015

COPD associated with increased mortality in patients with atrial fibrillation, but not stroke

Chronic obstructive pulmonary disease, or COPD, is associated with increased risk of dying from a cardiovascular disease such as heart failure or a heart attack, as well as diseases not associated with the heart. However, COPD is not by itself associated with increased likelihood of having a stroke or a systemic embolism, according to a new research study.

21 May 2015

New blood thinner reduces stroke risk in patients with atrial fibrillation

Patients with high-risk atrial fibrillation, or AFib, often require one drug to regulate heart rhythm and a second drug to thin their blood and reduce the risk of stroke.

9 Mar 2015