Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

High-fat diets inflame fat tissue surrounding blood vessels

A study by researchers at the University of Cincinnati (UC) shows that high-fat diets, even if consumed for a short amount of time, can inflame fat tissue surrounding blood vessels, possibly contributing to cardiovascular disease.

20 Feb 2009

VAP cholesterol test helps find link between a rare gene mutation and heart protection

Using the VAP Cholesterol Test from Atherotech, Inc., University of Maryland researchers have found an association between a rare gene mutation and heart protection.

17 Feb 2009

Study identifies gene variants associated with early-onset myocardial infarction

The largest study ever completed of genetic factors associated with heart attacks has identified nine genetic regions - three not previously described - that appear to increase the risk for early-onset myocardial infarction.

8 Feb 2009

Is rapid transition through menopause linked to earlier onset of heart disease?

An evaluation of 203 women as part of the multifaceted Los Angeles Atherosclerosis Study (LAAS) found that those who transitioned more quickly through menopause were at increased risk for a higher rate of progression of "preclinical atherosclerosis" - narrowing of arteries caused by the thickening of their walls.

29 Jan 2009

Assessing the real risk of heart disease in young people with low short-term risks

Risk stratification has become central to strategies for the prevention of coronary heart disease, with the implication that priority is given to those at highest risk (ie, those with established heart disease).

29 Jan 2009

Inflammation worsens danger due to atherosclerosis

Current research suggests that inflammation increases the risk of plaque rupture in atherosclerosis.

23 Jan 2009

Stroke telemedicine assessed

Stroke telemedicine is a lifesaving practice that deserves further advancement, Mayo researchers write in the January 2009 issue of Mayo Clinic Proceedings.

19 Jan 2009

Less severe first heart attacks linked to decline in coronary heart disease deaths

The severity of first heart attacks has dropped significantly in the United States - propelling a decline in coronary heart disease deaths, researchers reported in Circulation: Journal of the American Heart Association.

19 Jan 2009

Invatec launches drug-eluting balloon to treat atherosclerosis below the knee

Invatec, a comprehensive innovator of interventional products, today announced the European launch of a new peripheral balloon, the IN.PACT Amphirion paclitaxel-eluting PTA balloon catheter.

15 Jan 2009

Half of people 50 years and younger with low 10-year risk of CVD have high lifetime risk

About half of people 50 years and younger who have a low 10-year or short-term cardiovascular disease (CVD) risk may have a high lifetime risk, researchers report in Circulation: Journal of the American Heart Association.

15 Jan 2009

Oral contraceptives may be safe, but information gaps remain

Introduced in the 1960s, oral contraceptives have been used by about 80 percent of women in the United States at some point in their lives.

15 Jan 2009

Researchers find that healthy, younger adults could be at risk for heart disease

Even younger adults who have few short-term risk factors for heart disease may have a higher risk of developing heart disease over their lifetimes, according to new findings by a UT Southwestern Medical Center researcher.

12 Jan 2009

Australian discovers gene for deadly Kawasaki disease

An Australian researcher has identified genes which could make some children more susceptible to the deadly Kawasaki disease - an inflammatory condition in young children that can damage blood vessels.

12 Jan 2009

Phase 3 trial begins for Gammagard liquid plus rHuPH20 in primary immunodeficiency patients

Baxter International Inc. and Halozyme Therapeutics, Inc. gas announced the start of a Phase 3 clinical trial of Baxter's Gammagard Liquid [Immune Globulin Intravenous] 10% (IGIV), marketed as KIOVIG in the European Union, with Halozyme's recombinant human hyaluronidase enzyme (rHuPH20, Enhanze Technology) for the treatment of primary immunodeficiency (PID).

From Baxter International Inc. 5 Jan 2009

Neuropeptide Y gene variation may lead to early coronary artery disease

Researchers from Duke University Medical Center have identified a variation in a particular gene that increases susceptibility to early coronary artery disease.

5 Jan 2009

Measuring nanoparticle behavior in the body using MRI

One of the key steps in the development of any drug or imaging agent intended for human use is measurement of the adsorption, metabolism, and excretion of the drug.

29 Dec 2008

Two common biomarkers help predict stroke risk

Two common biomarkers have now been shown to improve the ability to predict who will suffer from a stroke.

18 Dec 2008

Single letter in the human genome points to risk for high cholesterol

Write out every letter in the human genome, one A, C, T or G per millimeter, and the text would be 1,800 miles long, roughly the distance from New York to Colorado.

16 Dec 2008

Discovery of link between inflamed gums and heart disease

The next person who reminds you to floss might be your cardiologist instead of your dentist. Scientists have known for some time that a protein associated with inflammation (called C-reactive protein) is elevated in people who are at risk for heart disease.

15 Dec 2008

Researchers create new family of fluorescent probes called hydrocyanines to detect reactive oxygen species in vivo

Researchers have created a new family of fluorescent probes called hydrocyanines that can be used to detect and measure the presence of reactive oxygen species.

15 Dec 2008

Atherosclerosis News and Research

Further Reading

High-fat diets inflame fat tissue surrounding blood vessels

VAP cholesterol test helps find link between a rare gene mutation and heart protection

Study identifies gene variants associated with early-onset myocardial infarction

Is rapid transition through menopause linked to earlier onset of heart disease?

Assessing the real risk of heart disease in young people with low short-term risks

Inflammation worsens danger due to atherosclerosis

Stroke telemedicine assessed

Less severe first heart attacks linked to decline in coronary heart disease deaths

Invatec launches drug-eluting balloon to treat atherosclerosis below the knee

Half of people 50 years and younger with low 10-year risk of CVD have high lifetime risk

Oral contraceptives may be safe, but information gaps remain

Researchers find that healthy, younger adults could be at risk for heart disease

Australian discovers gene for deadly Kawasaki disease

Phase 3 trial begins for Gammagard liquid plus rHuPH20 in primary immunodeficiency patients

Neuropeptide Y gene variation may lead to early coronary artery disease

Measuring nanoparticle behavior in the body using MRI

Two common biomarkers help predict stroke risk

Single letter in the human genome points to risk for high cholesterol

Discovery of link between inflamed gums and heart disease

Researchers create new family of fluorescent probes called hydrocyanines to detect reactive oxygen species in vivo

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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