Autophagy News and Research

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Autophagy is a normal process in which a cell destroys proteins and other substances in its cytoplasm (the fluid inside the cell membrane but outside the nucleus), which may lead to cell death. Autophagy may prevent normal cells from developing into cancer cells, but it may also protect cancer cells by destroying anticancer drugs or substances taken up by them.
New project to unravel secret lives of cancer cells may help produce new cancer therapies

New project to unravel secret lives of cancer cells may help produce new cancer therapies

MBL generates human monoclonal antibodies against pandemic A type influenza virus

MBL generates human monoclonal antibodies against pandemic A type influenza virus

Postdoctoral scientists receive prestigious award; grants totaling $1.54 million will help in funding innovative projects

Postdoctoral scientists receive prestigious award; grants totaling $1.54 million will help in funding innovative projects

IKK phosphorylate: A double-edged sword in Huntington's disease

IKK phosphorylate: A double-edged sword in Huntington's disease

Arno Therapeutics announces dosing of first patient in Phase II clinical study of AR-67

Arno Therapeutics announces dosing of first patient in Phase II clinical study of AR-67

Mutant ATPase blocks autophagy partway and causes multi-tissue degenerative disease

Mutant ATPase blocks autophagy partway and causes multi-tissue degenerative disease

Presentation of preclinical data demonstrating the combination of ISTODAX and Velcade announced

Presentation of preclinical data demonstrating the combination of ISTODAX and Velcade announced

Mutated IDH1 gene linked to the progression of gliomas

Mutated IDH1 gene linked to the progression of gliomas

Mutated IDH1 gene has novel enzyme activity consistent with cancer-causing gene: Study

Mutated IDH1 gene has novel enzyme activity consistent with cancer-causing gene: Study

AACR-NCI-EORTC conference highlights major expansion in cancer drug pipeline

AACR-NCI-EORTC conference highlights major expansion in cancer drug pipeline

HDAC inhibitors: New therapy for treating breast cancer

HDAC inhibitors: New therapy for treating breast cancer

Study: HSP inhibitor could stop tumor formation and extend survival

Study: HSP inhibitor could stop tumor formation and extend survival

Arno Therapeutics to commence Phase 1 clinical study of AR-12 in adult patients with lymphoma

Arno Therapeutics to commence Phase 1 clinical study of AR-12 in adult patients with lymphoma

Mid-career scientists receive the 2009 Julie Martin Mid-Career Awards in Aging Research

Mid-career scientists receive the 2009 Julie Martin Mid-Career Awards in Aging Research

Research points to new targets for melanoma

Research points to new targets for melanoma

Autophagy helps HIV to proliferate

Autophagy helps HIV to proliferate

Controlling the fate of cells

Controlling the fate of cells

Waste disposal protein key to cancer tumor suppression in autophagy

Waste disposal protein key to cancer tumor suppression in autophagy

Overexpression of PEA-15 protein shrinks breast cancer tumors

Overexpression of PEA-15 protein shrinks breast cancer tumors

Therapeutic effect of imatinib improved with addition of chloroquine

Therapeutic effect of imatinib improved with addition of chloroquine