Bacteriophage News and Research

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Bacteriophages are small, virus-like organisms that infect bacteria. They are comprised of a protein capsule around an RNA or DNA genome.

Structure of bacteriophage shown to resemble a human virus

New research has revealed that the structure of a bacteriophage, a virus infecting bacteria, resembles that of certain dangerous viruses that infect people.

26 Jun 2006

Anthrax killed by protein that explodes cell walls

Not all biological weapons are created equal. They are separated into categories A through C, category A biological agents being the scariest: They are easy to spread, kill effectively and call for special actions by the pubic health system. One of these worrisome organisms is anthrax, which has already received its fair share of media attention. But work in Vince Fischetti's laboratory at Rockefeller University suggests that a newly discovered protein could be used to fight anthrax infections and even decontaminate areas in which anthrax spores have been released.

26 Apr 2006

Researchers unmask secrets of a tiny virus that infects bacteria

Using powerful computer tools and cryo-electron microscopes, researchers at Baylor College of Medicine unmasked the secrets of a tiny virus that infects bacteria and, in doing so, opened the door to a better understanding of a variety of viruses that infect people and animals.

13 Feb 2006

Technique for inserting genes into specific sites on the genome in liver cells

The genes are inserted into non-coding regions of the genome so there is no danger of interfering with the functioning of other genes. Once inserted, the gene remains a permanent part of the cell's genome.

10 Oct 2005

22 biomarkers that provide a more accurate screening for prostate

Researchers at the University of Michigan Comprehensive Cancer Center have identified a panel of 22 biomarkers that together provide a more accurate screening for prostate cancer than the current prostate specific antigen, or PSA, test.

22 Sep 2005

Simple organism can produce 10 trillion varieties of a single protein

A team led by University of California, San Diego biochemists has discovered the mechanism by which a simple organism can produce 10 trillion varieties of a single protein, a finding that provides a new tool to develop novel drugs.

21 Sep 2005

Harmless bacterium can sometimes trigger outbreaks of life-threatening meningitis

Reporting in the June 20 issue of The Journal of Experimental Medicine, a group of scientists in Paris, France led by Colin Tinsley may have discovered how a normally harmless bacterium can sometimes trigger outbreaks of life-threatening meningitis.

20 Jun 2005

Engineers have found a way to modify a plastic to anchor molecules that promote nerve regeneration, blood vessel growth or other biological processes

In the study led by Dr. Christine Schmidt, the researchers identified a piece of protein from among a billion candidates that could perform the unusual feat of attaching to polypyrrole, a synthetic polymer (plastic) that conducts electricity and has shown promise in biomedical applications.

17 May 2005

Anti-nicotine vaccine to help smokers is promising

Swiss researchers say they have had some encouraging results with an experimental anti-nicotine vaccine.

15 May 2005

Chemical library aids in developing drug system for nerve damage

A researcher studying drug design for nerve damage therapies has gotten her answer to questions by following some old advice: she used the library.

12 Apr 2005

Rabies, HIV, cancer and malaria could all be prevented with pills in the future

Rabies, HIV, cancer and malaria could all be prevented with pills in the future, if a new technique using specially modified viruses to deliver vaccines is adopted, according to scientists speaking today (Tuesday, 05 April 2005) at the Society for General Microbiology's 156th Meeting at Heriot-Watt University, Edinburgh.

4 Apr 2005

Nylon strips an effective weapon against the hospital acquired superbug

Nylon strips, beads and hospital stitching thread covered in viruses could be an effective weapon against the hospital acquired superbug, methicillin-resistant Staphylococcus aureus, known as MRSA, according to research presented today (Tuesday, 05 April 2005) at the Society for General Microbiology's 156th Meeting at Heriot-Watt University, Edinburgh.

4 Apr 2005

Washing hands with soap and water best protection against disease-causing viruses

The largest, most comprehensive study ever done comparing the effectiveness of hand hygiene products shows that nothing works better in getting rid of disease-causing viruses than simply washing one's hands with good old-fashioned soap and water.

14 Mar 2005

DNA ejection from single phage particles

Studying phage, a primitive class of virus that infects bacteria by injecting its genomic DNA into host cells, researchers have gained insight into the driving force behind this poorly understood injection process, which has been proposed in the past to occur through the release of pressure accumulated within the viral particle itself.

7 Mar 2005

Crystallized molecular machine reveals possible new paths for treating diseases

The crystallized form of a molecular machine that can cut and paste genetic material is revealing possible new paths for treating diseases such as some forms of cancer and opportunistic infections that plague HIV patients.

21 Feb 2005

Laboratory test of evolutionary theory confirms the importance of connections between populations

Researchers studying the evolutionary dynamics of bacteria and viruses in bubbling glass tubes have confirmed an evolutionary theory of central importance to ecologists studying more familiar flora and fauna in the wild.

13 Oct 2004

Researchers have successfully targeted an HIV protein that has eluded existing therapies

Researchers targeted Nef, a protein responsible for accelerating the development of acquired immunodeficiency syndrome, or AIDS. Nef was targeted with small molecules synthesized by the researchers – molecules that disrupted Nef’s interaction with other proteins.

26 Sep 2004