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Copper sequestering drug tetrathiomolybdate shown to be effective in treating Wilson disease

The copper sequestering drug tetrathiomolybdate (TM) has been shown in studies to be effective in the treatment of Wilson disease, a disease caused by an overload of copper, and certain metastatic cancers.

27 Nov 2009

Wnt and EGFR signaling pathways interact to promote tumor cell invasion and metastasis

Two signaling pathways essential to normal human development - the Wnt/Wingless (Wnt) and epidermal growth factor receptor (EGFR) pathways - interact in ways that can promote tumor cell invasion and metastasis, researchers from The University of Texas M. D. Anderson Cancer Center report in the Nov. 25 issue of Molecular Cell.

26 Nov 2009

Cells protect themselves against viruses and bacteria with novel non-genetic mechanism

When cells are confronted with an invading virus or bacteria or exposed to an irritating chemical, they protect themselves by going off their DNA recipe and inserting the wrong amino acid into new proteins to defend them against damage, scientists have discovered.

26 Nov 2009

Lethality of H1N1 virus has dropped from its peak of 3.7, shows new data

Biotech firm Replikins Ltd., which has analyzed the H1N1 virus' genomic data from the 1918 pandemic through the prediction, outbreak, and progress of the current H1N1 pandemic, today issued its latest biochemical analysis of the virus.

25 Nov 2009

Mutated IDH1 gene linked to the progression of gliomas

23 Nov 2009

Mutated IDH1 gene has novel enzyme activity consistent with cancer-causing gene: Study

Agios Pharmaceuticals today announced that its scientists have established, for the first time, that the mutated IDH1 gene has a novel enzyme activity consistent with a cancer-causing gene, or oncogene. This breakthrough discovery shows that the mutated form of IDH1 produces a metabolite, 2-hydroxyglutarate (2HG), which may contribute to the formation and malignant progression of gliomas, the most common type of brain cancers.

23 Nov 2009

Foods rich in antioxidant substances could delay the onset of Alzheimer's disease

Universitat Autònoma de Barcelona (UAB) researchers have confirmed that a diet rich in polyphenols and polyunsaturated fatty acids, patented as an LMN diet, helps boost the production of the brain's stem cells -neurogenesis- and strengthens their differentiation in different types of neuron cells.

23 Nov 2009

Scientists closer to unraveling the mechanisms of gene regulation

A team led by Penn State's Ross Hardison, T. Ming Chu Professor of Biochemistry and Molecular Biology, has taken a large step toward unraveling how regulatory proteins control the production of gene products during development and growth.

20 Nov 2009

University of Leeds scientists' discovery could lead to new treatment route for BSE and CJD

A new treatment route for bovine spongiform encephalopathy (BSE) and its human form Creutzfeldt Jakob disease (CJD) could be a step closer thanks to a discovery by scientists at the University of Leeds.

20 Nov 2009

New photocontrolled molecular switch regulates paralysis in living organisms

In an advance with overtones of Star Trek phasers and other sci-fi ray guns, scientists in Canada are reporting development of an internal on-off "switch" that paralyzes animals when exposed to a beam of ultraviolet light. The animals stay paralyzed even when the light is turned off. When exposed to ordinary light, the animals become unparalyzed and wake up.

19 Nov 2009

Fully integrated human genome sequencing and data processing service launched

Knome, Inc., a recognized pioneer in the personal genomics field, today announced the launch of KnomeDISCOVERY, the first fully integrated human genome sequencing and data processing service for researchers. The new offering meets rapidly emerging demand from biomedical researchers for a one-stop service that bundles affordable, research-tailored access to a broad range of next-generation sequencing platforms with discovery-supportive data management and analysis.

18 Nov 2009

Enzo Biochem to market GeneNews’ ColonSentry in New York and New Jersey

Enzo Biochem, Inc. (NYSE:ENZ) today announced that it has entered into an agreement with GeneNews (TSX: GEN), of Toronto, Canada, for exclusive rights to market GeneNews’ ColonSentry™, a proprietary blood test for colorectal cancer, in the states of New York and New Jersey.

18 Nov 2009

MPI scientists identify mechanism that demonstrates immune cell movement on diverse surfaces

Scientists from the Max Planck Institute (MPI) of Biochemistry in Martinsried near Munich, Germany, have now deciphered the mechanism that illustrates how these mobile cells move on diverse surfaces. "Similar to a car, these cells have an engine, a clutch and wheels which provide the necessary friction," explains Michael Sixt, a research group leader at the MPI of Biochemistry.

18 Nov 2009

Gene that tells embryonic stem cells when to stop producing neurons identified

Researchers from North Carolina State University have identified a gene that tells embryonic stem cells in the brain when to stop producing nerve cells called neurons. The research is a significant advance in understanding the development of the nervous system, which is essential to addressing conditions such as Parkinson's disease, Alzheimer's disease and other neurological disorders.

18 Nov 2009

Antioxidant found in vegetables can protect cells from damage caused by infection and injury

Scientists at the University of Pennsylvania School of Medicine discovered that a dietary antioxidant found in such vegetables as broccoli and cauliflower protects cells from damage caused by chemicals generated during the body's inflammatory response to infection and injury. The finding has implications for such inflammation-based disorders as cystic fibrosis (CF), diabetes, heart disease, and neurodegeneration.

17 Nov 2009

NIH awards $3 million grant to ASU professors for research on rapid DNA sequencing technology

Arizona State University has been awarded nearly $3 million in federal stimulus funds from the National Institutes of Health. ASU professors Stuart Lindsay and Paul Westerhoff will lead a pair of two-year, innovative projects designed to tackle challenges in the fields of rapid DNA sequencing and the potential health risks of nanotechnology.

17 Nov 2009

NRC helps Olympus to design and commercialize CARS microscope

The National Research Council Canada (NRC) recently helped Olympus, a world leader in advanced optical microscopy and medical imaging, to design and commercialize a CARS (Coherent Anti-stokes Raman Scattering) microscope.

From Evident Corporation - Life Sciences 16 Nov 2009

Toray Industries announces award for groundbreaking research that uses DNA microarray analysis

Toray Industries, Inc. (TOKYO:3402) of Japan announces a competition award for groundbreaking research that uses DNA microarray analysis.

16 Nov 2009

Normal synaptic activity in nerve cells protects brain from Huntington's disease

Investigators at Burnham Institute for Medical Research (Burnham), the University of British Columbia's Centre for Molecular Medicine and Therapeutics and the University of California, San Diego have found that normal synaptic activity in nerve cells (the electrical activity in the brain that allows nerve cells to communicate with one another) protects the brain from the misfolded proteins associated with Huntington's disease.

16 Nov 2009

Scientists describe how HIV assemble at the membrane of infected cells and are released to attack healthy cells

Although recent advances have raised hopes that a protective vaccine can be developed, acquired immunodeficiency syndrome (AIDS) remains a major public health problem. Much has been learned about HIV-1, the virus that causes the disease.

13 Nov 2009

Biochemistry News and Research

Copper sequestering drug tetrathiomolybdate shown to be effective in treating Wilson disease

Wnt and EGFR signaling pathways interact to promote tumor cell invasion and metastasis

Cells protect themselves against viruses and bacteria with novel non-genetic mechanism

Lethality of H1N1 virus has dropped from its peak of 3.7, shows new data

Mutated IDH1 gene linked to the progression of gliomas

Mutated IDH1 gene has novel enzyme activity consistent with cancer-causing gene: Study

Foods rich in antioxidant substances could delay the onset of Alzheimer's disease

Scientists closer to unraveling the mechanisms of gene regulation

University of Leeds scientists' discovery could lead to new treatment route for BSE and CJD

New photocontrolled molecular switch regulates paralysis in living organisms

Fully integrated human genome sequencing and data processing service launched

Enzo Biochem to market GeneNews’ ColonSentry in New York and New Jersey

MPI scientists identify mechanism that demonstrates immune cell movement on diverse surfaces

Gene that tells embryonic stem cells when to stop producing neurons identified

Antioxidant found in vegetables can protect cells from damage caused by infection and injury

NIH awards $3 million grant to ASU professors for research on rapid DNA sequencing technology

NRC helps Olympus to design and commercialize CARS microscope

Toray Industries announces award for groundbreaking research that uses DNA microarray analysis

Normal synaptic activity in nerve cells protects brain from Huntington's disease

Scientists describe how HIV assemble at the membrane of infected cells and are released to attack healthy cells

Biochemistry eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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