Biochemistry News and Research

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Which came first, nucleic acids or proteins?

Which came first, nucleic acids or proteins? This question is molecular biology's version of the "chicken-or-the-egg" riddle.

24 Jul 2006

Digital magnetofluidics holds hope for better medicine

Critical advances in medicine and environmental protection promise to emerge from a new method for biochemical analysis of fluids developed by an international science team led in part by Arizona State University researchers.

21 Jul 2006

An accurate model of p53 tumor suppressor protein bound to DNA for anti-cancer activity

More than half of human cancers involve mutations in the p53 tumor-suppressor gene, suggesting the critical role played by the normal p53 protein in defending against cancer.

18 Jul 2006

New ways to synthesize Antascomicin B

The molecule Antascomicin B has the potential to both regenerate nerve growth and help scientists better understand immune system suppression in organ transplants

17 Jul 2006

Listeriosis and pregnancy

For years, doctors have puzzled over why pregnant women are 20 times more likely than others to be infected by the bacterium Listeria monocytogenes. Researchers at the University of California, Berkeley, now think they have the answer, and it isn't pretty.

3 Jul 2006

Probable cause for Parkinson's found

Parkinson's, Alzheimer's, Lou Gehrig's disease and other brain disorders are among a growing list of maladies attributed to oxidative stress, the cell damage caused during metabolism when the oxygen in the body assumes ever more chemically reactive forms.

28 Jun 2006

Green leaves may fight obesity

Could a substance found in green leaves be used as a means of combating obesity, by being added to various functional foods to keep the consumer feeling full longer?

26 Jun 2006

Dietary glycemic index and carbohydrate in relation to early age-related macular degeneration

Age-related macular degeneration (AMD) is one of the leading causes of vision loss in older adults and a person's risk may partly depend upon diet.

6 Jun 2006

Milstein gift seeks cure for antibiotic-resistant TB and malaria

A $7.25 million gift to Weill Medical College of Cornell University will establish the Abby and Howard P. Milstein Chemistry Core Facility and the Abby and Howard P. Milstein Program in Chemical Biology.

5 Jun 2006

COX-1 and COX-2 enzymes may be blocked by pain medications

COX-1 and COX-2 enzymes may be blocked by pain medications such as Advil and Vioxx in a more complex manner than was previously understood, a Queen's University study has found.

29 May 2006

NIH panel says little benefit to be gained by taking multivitamin supplements

According to a National Institutes of Health panel there is little evidence to support that taking multivitamin supplements is of any benefit to healthy adults.

21 May 2006

Panel calls for expanded oversight of vitamin and mineral supplements

An independent panel convened this week by the NIH Office of Medical Applications of Research and the Office of Dietary Supplements assessed the available evidence on the safety and effectiveness of multivitamin/minerals (MVMs).

17 May 2006

German scientists synthesize new compound that reduces stroke damage

A group of German scientists has synthesized a new compound that dramatically decreases the damage to neurons in rats demonstrating stroke symptoms.

16 May 2006

Novel protein JHDM2A offers new look at male hormone regulation

For the second time in less than a year, University of North Carolina at Chapel Hill scientists have purified a novel protein and have shown it can alter gene activity by reversing a molecular modification previously thought permanent.

8 May 2006

Discovery of gene that appears to play an important role in the onset of type 2 diabetes

In a painstaking set of experiments in overweight mice, scientists from the University of Wisconsin-Madison have discovered a gene that appears to play an important role in the onset of type 2 diabetes.

8 May 2006

Bacterial binding in the stomach

Scientists have determined that decay-accelerating factor (DAF), a protein found in epithelial cells in the stomach, acts as a receptor for the bacteria Helicobacter pylori. Blocking this interaction could lead to new drugs that reduce the risk of peptic ulcer disease or gastric cancer.

8 May 2006

DARPA grant supports research toward realizing tissue regeneration

While U.S. soldiers fighting in Iraq and Afghanistan are surviving injuries that in previous conflicts likely would have been fatal, the number of wounded with major tissue loss has never before been so high.

3 May 2006

Scientists create leaner and meaner E. coli

By stripping the E. coli genome of vast tracts of its genetic material - hundreds of apparently inconsequential genes - a team of Wisconsin researchers has created a leaner and meaner version of the bacterium that is a workhorse of modern biology and industry.

3 May 2006

Progressive histological damage in liver allografts following pediatric liver transplantation

A new study on the long-term outcome of children undergoing liver transplants found that chronic hepatitis (CH) was common and that it was not detectible using standard blood tests.

3 May 2006

Enzyme discovery could reduce Kaposi sarcoma tumour growth and lead to drugs suitable for treating other viral cancers

A report in the Journal of Biological Chemistry shows that inhibition of heme oxygenase-1, an enzyme involved in iron metabolism, reduces Kaposi sarcoma tumor growth. This discovery could result in the production of new drugs to treat this and other viral cancers.

28 Apr 2006