Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

1/4 human tumor exist genetic polymorphisms linked with increased risk of cancer

In 10% of human tumors there is a family history of hereditary disease associated with mutations in identified genes. The best examples are the cases of polyps in the large intestine associated with the APC gene and breast cancer associated with BRCA1 and BRCA2 genes.

11 Apr 2014

Comprehensive genomic analysis of low-grade brain tumors sorts into three categories

Comprehensive genomic analysis of low-grade brain tumors sorts them into three categories, one of which has the molecular hallmarks and shortened survival of glioblastoma multiforme, the most lethal of brain tumors, researchers reported at the American Association for Cancer Research Annual Meeting 2014.

10 Apr 2014

Biologists find ways to address antibiotic resistance

Biologists could gain a deeper understanding about how species have evolved - and even find ways to address antibiotic resistance - using tools that were developed recently at Stockholm's KTH Royal Institute of Technology.

8 Apr 2014

Researchers discover hotspot L205R mutation is closely associated with adrenocortical tumors

Chinese researchers from Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, BGI, and other institutions have discovered that the activating hotspot L205R mutation in PRKACA gene was closely associated with adrenocortical tumors (ACTs), and the relationship of recurrently mutated DOT1L and CLASP2 with ACTs' other subtypes.

7 Apr 2014

Blood sample could diagnose many types of solid cancers

A blood sample could one day be enough to diagnose many types of solid cancers, or to monitor the amount of cancer in a patient's body and responses to treatment. Previous versions of the approach, which relies on monitoring levels of tumor DNA circulating in the blood, have required cumbersome and time-consuming steps to customize it to each patient or have not been sufficiently sensitive.

7 Apr 2014

QIAGEN launches new products for next-generation sequencing applications

QIAGEN N.V. today announced two important new product launches which address workflow challenges in next-generation sequencing (NGS) applications.

From QIAGEN Manchester Limited 3 Apr 2014

UM researchers awarded FDA contract to expand high-throughput sequencing database

Researchers at the Institute for Genome Sciences at the University of Maryland School of Medicine have been awarded a research program contract from the U.S. Food and Drug Administration (FDA) to sequence, assemble, and annotate a population of bacterial pathogens using two high-throughput sequencing (HTS) technologies in support of the expansion of a vetted public reference database.

2 Apr 2014

2014 Biotech China to be held on 14-16 May in Nanjing, China

Biotech China, the first major Chinese biotech exhibition and conference, will hold the 2014 Biotech China on 14-16th May, 2014 in Nanjing, China.

27 Mar 2014

Researchers release first comprehensive atlas of human gene expression

A large international consortium of researchers has produced the first comprehensive, detailed map of the way genes work across the major cells and tissues of the human body. The findings describe the complex networks that govern gene activity, and the new information could play a crucial role in identifying the genes involved with disease.

27 Mar 2014

FMCNA introduces newly branded Frenova Renal Research business

Fresenius Medical Care North America, the world's largest provider of dialysis services, today introduced its newly branded Frenova Renal Research business, the only Phase I-IV drug and device clinical development partner dedicated exclusively to renal research.

26 Mar 2014

Findings reveal potential drug targets for small cell lung cancer

Cancer cells undergo extensive genetic alterations as they grow and spread through the body. Some of these mutations, known as "drivers," help spur cells to grow out of control, while others ("passengers") are merely along for the ride.

17 Mar 2014

Scientists discover gene variation that makes humans have healthier blood lipid levels, reduced risk of heart attacks

Scientists have discovered a previously unrecognized gene variation that makes humans have healthier blood lipid levels and reduced risk of heart attacks -- a finding that opens the door to using this knowledge in testing or treatment of high cholesterol and other lipid disorders.

17 Mar 2014

UC Davis MIND Institute named Intellectual and Developmental Disabilities Research Center

The UC Davis MIND Institute has been named an Intellectual and Developmental Disabilities Research Center, through a prestigious grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health - a distinction held by only a handful of neurodevelopmental centers nationwide committed to the diagnosis, prevention, treatment and amelioration of developmental disorders such as autism, fragile X syndrome and Down syndrome.

14 Mar 2014

Researchers use computer-aided design tool to create genetic languages of biological systems

Researchers at Virginia Tech and the Massachusetts Institute of Technology have used a computer-aided design tool to create genetic languages to guide the design of biological systems.

14 Mar 2014

Researchers explore how genetics affects causes and prevalence of preterm birth

More than 450,000 babies are born too soon each year in the U.S. Preterm birth is a serious health problem that costs the nation more than $26 billion annually, according to the Institute of Medicine, and is the leading cause of newborn death.

12 Mar 2014

Teen researcher wins top award from Intel Foundation for research on potential drugs to treat influenza

From new cancer treatments to an exploration of how technology affects the adolescent brain, the innovative research of America's future scientists, engineers and inventors took center stage in the nation's capital today.

12 Mar 2014

Researchers seek to understand causes of premature birth with support from March of Dimes

Five researchers seeking to understand the causes of premature birth with the goal of identifying women at risk of preterm labor and developing new treatments to prevent it have been awarded grant support from the March of Dimes.

10 Mar 2014

Researchers find unusual mutation strongly linked to rare liver cancer that affects teens

In the race for better treatments and possible cures, rare diseases are often left behind. In a collaboration of researchers at The Rockefeller University, Memorial Sloan Kettering Cancer Center and the New York Genome Center (NYGC), an unusual mutation has been found that is strongly linked to one such disease: a rare liver cancer that affects teens and young adults.

3 Mar 2014

Teen diagnosed with liver cancer explores genetic link to rare cancers

A father-daughter scientific collaboration that began after the daughter was diagnosed with a rare liver cancer has led to an important finding and could have broader implications for many other rare cancers. Their story is being published this week in a top tier journal, Science.