Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

EdgeBio introduces Science as a Service concept built on top of CLC Genomics Server

Today at the inaugural Beyond Sequencing conference in San Francisco, EdgeBio introduced their Science as a Service concept built on top of CLC bio's enterprise platform, CLC Genomics Server. EdgeBio's end-to-end service concept leads each scientist and project from conception and project design through bioinformatics and analysis.

23 Jun 2010

Mayo Clinic, University of Illinois announce strategic alliance for technology-based health care

Mayo Clinic and the University of Illinois at Urbana-Champaign are announcing a strategic alliance designed to promote a broad spectrum of collaborative research, development of new technologies and clinical tools, and design and implementation of novel education programs. Both parties recently signed an agreement establishing the formal relationship.

23 Jun 2010

International team obtains genome sequence of human body louse

An international team has obtained the genome sequence of the human body louse (Pediculus humanus humanus), a parasite that feeds on the blood of its host and a vector of pathogens that cause diseases such as epidemic typhus, relapsing fever and trench fever.

22 Jun 2010

AMP raises ethical, laboratory practice concerns in whole genome sequencing at SACHGS meeting

Today, the Association for Molecular Pathology (AMP) presented public comments to the Secretary's Advisory Committee on Genetics, Health and Society (SACHGS) meeting focused on whole genome sequencing. In anticipation of advances in sequencing and its incorporation into clinical practice, AMP raised ethical and laboratory practice concerns for the Committee's consideration.

17 Jun 2010

Researchers sequence genome of Amerindian strain of the gastric bug H. pylori

An international team of researchers led by scientists at the Virginia Bioinformatics Institute at Virginia Tech have sequenced the genome of an Amerindian strain of the gastric bug Helicobacter pylori, confirming the out-of-Africa migration of this bacterial stowaway to the New World. Experiments in animals have highlighted how specific genes in the bacterial strain may be crucial to the onset of inflammation and disease.

17 Jun 2010

AVEO granted patents for tests to identify cancer patients likely to respond to tivozanib

AVEO Pharmaceuticals, Inc., a biopharmaceutical company focused on discovering, developing and commercializing cancer therapeutics, today announced the issuance of U.S. Patent Nos. 7,615,353, which issued in November 2009, and 7,736,861, which issued yesterday.

16 Jun 2010

CLC bio headed molecular diagnostics project receives $2M grant

CLC bio, Ion Torrent, and Aarhus University Hospital - Departments of Molecular Medicine and Clinical Genetics, have received a 2 million USD grant from the Danish National Advanced Technology Foundation.

15 Jun 2010

Researchers discover microRNA biomarkers to treat patients with SCLC

Researchers at the Translational Genomics Research Institute, the Van Andel Research Institute and the Virginia G. Piper Cancer Center at Scottsdale Healthcare have discovered a biomarker that could help in the treatment of patients with an aggressive type of lung cancer.

15 Jun 2010

Ion Torrent extends Ion PGM Sequencer Grant Program to Europe

Ion Torrent today announced that it is extending its Ion PGM Sequencer Grant Program to Europe, and will award two sequencers to scientists there in the second half of 2010. This spring Ion Torrent received hundreds of grant proposals from scientists in North America, and in April two winners were each awarded an Ion PGM sequencer.

11 Jun 2010

Scientists develop algorithm to predict gene sequence of kinases

Kinexus Bioinformatics Corporation, a world-leader in molecular communications research, announced major advancements in its PhosphoNET KnowledgeBase for the study of cell signalling systems. This free resource to the scientific community now features data on more than 92,000 human phosphorylation sites, including their occurrence in over 20 other diverse species, and identification of the protein kinases that target these regulatory sites.

9 Jun 2010

Delicate balance of microbes in vagina can vary between healthy women: New study

The delicate balance of microbes in the vagina can vary greatly between healthy women, according to a new study led by the University of Maryland School of Medicine's Institute for Genome Sciences. Researchers hope further study will lead to personalized reproductive medicine for women, allowing doctors to tailor each woman's treatment and health maintenance strategies to her individual microbial make-up.

4 Jun 2010

EMBL scientists identify two small RNA molecules that ensure red blood cell production

Red blood cells, the delivery men that take oxygen to cells all around the body, have short lives. To keep enough of them in circulation, the human body produces around 2 million of these cells every second - even more in response to challenges like severe blood loss. In a study published today in the Journal of Experimental Medicine, scientists at the European Molecular Biology Laboratory in Monterotondo, Italy, and EMBL's European Bioinformatics Institute in Hinxton, UK, have identified two small RNA molecules which ensure that enough red blood cells are produced efficiently, by fine-tuning a number of different genes involved in this process.

2 Jun 2010

Roche launches GS Junior System benchtop DNA sequencing platform for life science research

Roche, announced today the global launch of the GS Junior System, the company's new benchtop next-generation DNA sequencing platform for life science research. The GS Junior System, developed by 454 Life Sciences, a Roche company, provides an integrated sequencing and bioinformatics solution, all in a size that is no bigger than a typical desktop laser printer.

From Roche Sequencing and Life Science 28 May 2010

Genentech uses Complete Genomics' sequencing service to compare primary lung tumor, adjacent normal tissue

Complete Genomics Inc., a third-generation human genome sequencing company, today announced that Genentech Inc., a wholly owned member of the Roche Group, used the company's sequencing, bioinformatics and analytics services to sequence and compare a patient's primary lung tumor and adjacent normal tissue.

27 May 2010

Researchers use zebrafish as model to analyze function of every known mutation in BBS

A research team led by scientists from the Duke University Medical Center has developed a way to simultaneously look at the effects of 125 mutations occurring on 14 different genes. They used zebrafish as a model to analyze the function of every known mutation in an inherited syndrome called BBS, Bardet-Biedl Syndrome.

25 May 2010

GSK, EMBL-EBI, NLM and CDD collaborate to apply principles of open source to drug discovery for malaria

GlaxoSmithKline (GSK) had teamed up with leading public-domain data providers European Bioinformatics Institute (EMBL-EBI), the U.S. National Library of Medicine (NLM) and the U.S.-based informatics service provider Collaborative Drug Discovery (CDD) to make freely available key scientific information on more than 13,500 compounds that could ultimately lead to new treatments for malaria.

20 May 2010

UAMS and partners receive $14.7M NIH grant for extension of biomedical research

Biomedical research in Arkansas has received a $14.7 million boost over five years from the National Institutes of Health (NIH) to continue expanding and improving biomedical research in the state.

20 May 2010

VBI researchers establish new tree of life for gamma-proteobacteria

A new "tree of life" has been constructed by researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech for the gamma-proteobacteria, a large group of medically and scientifically important bacteria that includes Escherichia coli, Salmonella typhimurium, and other disease-causing organisms.

18 May 2010

ISCA recommends chromosomal microarray as new standard for genetic evaluation of children

An international consortium of genetics experts has issued a consensus statement recommending chromosomal microarray (CMA) as the new standard practice for genetic evaluation of children with unexplained developmental delay, autism or birth defects.

14 May 2010

Sanford-Burnham Scientific Symposium provides wealth of information on microRNAs, RNAi

Investigators from around the country came to Sanford-Burnham Medical Research Institute (Sanford-Burnham) on Friday, May 7, to share their knowledge of the burgeoning young field of microRNAs. These small non-coding nucleic acids turn off proteins and have been implicated in viral infection, cancer, cardiovascular disease, HIV and numerous other conditions.

12 May 2010