Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

True nature of heterochromatin revealed

Not so long ago, the difficult-to-sequence, highly repetitive, gene-poor DNA found in regions of chromosomes known as heterochromatin was called "junk." Like dark matter in the universe, the true nature of heterochromatin was unknown.

19 Jun 2007

Circadian rhythms and genetics

New research from Colorado State University shows that the function of all genes in mammals is based on circadian -- or daily -- rhythms. The study, publishing in PLoS Computational Biology on June 15, refutes the current theory that only 10 percent to 15 percent of all genes were affected by nature's clock.

18 Jun 2007

Largest ever Affymetrix GeneChip Microarray study

The Virginia Bioinformatics Institute (VBI) at Virginia Tech has announced that it has completed the largest ever Affymetrix GeneChip Microarray study for a plant experimental system in an academic research setting.

28 May 2007

First draft of the genome sequence of Aedes aegypti mosquito

Developing new strategies to prevent and control yellow fever and dengue fever has become more possible with the completion of the first draft of the genome sequence of Aedes aegypti mosquito by scientists led by Vishvanath Nene at The Institute for Genomic Research (TIGR) and David Severson at the University of Notre Dame.

18 May 2007

Cocoa extract may be an effective natural alternative to fluoride in toothpaste

For a healthy smile brush between meals, floss regularly and eat plenty of chocolate.

17 May 2007

Model of proline dehydrogenase created

Researchers at the University of Missouri-Columbia recently created a model of proline dehydrogenase, an important cancer-preventing enzyme in the human body, and analyzed how it works.

17 May 2007

Study looks at interest level of healthy, young adults in receiving genetic testing for common conditions

The National Human Genome Research Institute (NHGRI) and the National Cancer Institute (NCI), parts of the National Institutes of Health (NIH), have teamed with Group Health Cooperative in Seattle and Henry Ford Health System in Detroit to launch a study to investigate the interest level of healthy, young adults in receiving genetic testing for eight common conditions.

8 May 2007

Renewal of Echinacea and St John's Wort research

A five-year-old research center dedicated to understanding and improving Echinacea and Hypericum perforatum (St. John's wort) has received $4.4 million in continuation funding from the National Institutes of Health. The renewal is for three years.

4 May 2007

Fred Hutchinson Cancer Research Center establishes new vaccine and disease institute

Fred Hutchinson Cancer Research Center has established a new Vaccine and Infectious Disease Institute to develop and implement prevention strategies for globally important infectious diseases, including HIV, malaria and cancer.

2 May 2007

New searchable influenza gene database

A Medical College of Wisconsin and Children's Research Institute team in Milwaukee has created a free, searchable genetic database that will significantly improve diagnostic testing and genetic tracking of human and animal influenza viruses.

26 Apr 2007

Scientists discover new virus responsible for deaths of 3 transplant recipients

Scientists in the Greene Infectious Disease Laboratory of the Columbia University Mailman School of Public Health and colleagues in the Victorian Infectious Diseases Reference Laboratory in Melbourne, Australia and 454 Life Sciences have discovered a new virus that was responsible for the deaths of three transplant recipients who received organs from a single donor in Victoria, Australia.

24 Apr 2007

Discovery of new virus

24 Apr 2007

H5N1 western genomes sequenced

In a paper in the May issue of Emerging Infectious Diseases , an international team of researchers report the first ever large-scale sequencing of western genomes of the deadly avian influenza virus, H5N1.

17 Apr 2007

Macaque genome analysis will improve scientists' ability to identify human genes involved in diseases

Cornell experts in computational biology and bioinformatics have made key contributions to the analysis of the genome of the rhesus macaque, better known as the rhesus monkey.

15 Apr 2007

Analysis of Rhesus monkey genome provides new clues to primate biology

An international consortium of researchers has published the genome sequence of the rhesus macaque monkey and aligned it with the chimpanzee and human genomes.

12 Apr 2007

Almac announces study on colorectal pre-malignancies

Almac Diagnostics has announced a major study analysing colorectal polyp tissue samples using its novel Colorectal Cancer DSA microarray.

5 Apr 2007

Scientists discover new approach for treating virus-induced lymphomas

Kaposi's sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi's sarcoma and primary effusion lymphoma (PEL). PELs are aggressive lymphomas with reported median survival time shorter than six months after diagnosis.

19 Mar 2007

New drug target for herpes viruses

Scientists in the lab of Whitehead Institute Member Hidde Ploegh and the Harvard University lab of Rachelle Gaudet have solved the complex structure of a recently discovered protein that is found in a wide range of herpes viruses. This protein may prove to be a potential drug target.

11 Mar 2007

New drug target for herpes viruses

11 Mar 2007

Drug delivery system that consists of nanocrystals of a hydrophobic drug

The problem of efficiently delivering drugs, especially those that are hydrophobic or water-repellant, to tumors or other disease sites has long challenged scientists to develop innovative delivery systems that keep these drugs intact until reaching their targets.

8 Mar 2007