Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

New NIH grants support research that combines DNA sequence information and electronic medical records

A dozen awards from the National Institutes of Health will support research that incorporates DNA sequence information into electronic medical records. The goal of research conducted by the Electronic Medical Records and Genomics (eMERGE) network is to better understand the genomic basis of disease and to tailor medical care to individual patients based on their genomic differences.

2 Sep 2015

U-M study suggests potential treatment options for children with aggressive, advanced cancer

For children with rare, aggressive and advanced cancer, precision medicine may help doctors determine their best treatment options, a new study finds.

2 Sep 2015

Autism Speaks launches web-based portal for MSSNG database

Autism Speaks, the world's leading autism science and advocacy organization, today launched the web-based portal for its MSSNG database, making the resource available to researchers worldwide.

1 Sep 2015

Researchers identify druggable target to potentially root out colon cancer, end relapse

Researchers targeting colorectal cancer stem cells - the root cause of disease, resistance to treatment and relapse - have discovered a mechanism to mimic a virus and potentially trigger an immune response to fight the cancer like an infection.

28 Aug 2015

Researchers uncover important cellular functions that help regulate inflammation

Researchers at the Virginia Bioinformatics Institute at Virginia Tech have uncovered key cellular functions that help regulate inflammation -- a discovery that could have important implications for the treatment of allergies, heart disease, and certain forms of cancer.

28 Aug 2015

Analysis of toilet waste from international aircraft may lead to global surveillance of infectious diseases

Current international disease surveillance systems are mainly based on reports made by doctors after treatment of infected patients. As a consequence, disease-causing microorganisms and resistance bacteria have time to spread and make large population groups sick before they are detected.

20 Aug 2015

New study uses donor sample to evaluate how self-identification measures intersect with genetics

For years, medicine has relied on self-reported race/ethnicity as the basis of an array of decisions, from risk for disease to matching organ donors. Now, a study led by researchers at UC San Francisco has found that when that information matters most - in connecting bone marrow donors to patients - the format of the questions may determine how well the answers actually correspond to their genes.

20 Aug 2015

Penn State College of Medicine students to work with medical educators to design new curriculum

The medical school model that has existed for decades involves two years of study in the basic sciences followed by two years of clinical study. An initiative under way at Penn State College of Medicine will involve students in developing a new curriculum that integrates the two areas of study, with a goal of preparing physicians for the new realities of health care.

20 Aug 2015

Newly developed big data technique may have significant impact on health care

Rice University scientists have developed a big data technique that could have a significant impact on health care. The Rice lab of bioengineer Amina Qutub designed an algorithm called "progeny clustering" that is being used in a hospital study to identify which treatments should be given to children with leukemia.

13 Aug 2015

Researchers develop user-friendly platform for analyzing transcriptomic and epigenomic big data

Researchers at Cincinnati Children's Hospital Medical Center have developed a user-friendly, integrated platform for analyzing the transcriptomic and epigenomic "big data."

12 Aug 2015

Researchers create new cell screening method for immunotherapy cancer treatments

Researchers have created a new method for screening cells used in immunotherapy cancer treatments, allowing high-performing immune system cells to be studied in isolation and potentially expanding the number of patients for whom the breakthrough treatment proves successful.

11 Aug 2015

Study may lead to effective antimicrobial treatment strategies for people with uncontrolled diabetes

Case Western Reserve scientists may have uncovered a molecular mechanism that sets into motion dangerous infection in the feet and hands often occurring with uncontrolled diabetes. It appears that high blood sugar unleashes destructive molecules that interfere with the body's natural infection-control defenses.

7 Aug 2015

Discovery may lead to new ways to diagnose, treat brain cancer

Researchers at the Virginia Bioinformatics Institute have uncovered a link between the genomes of cells originating in the neural crest and development of tumors — a discovery that could lead to new ways to diagnose and treat cancer.

6 Aug 2015

Research: Critical aspects of human genome's regulatory program encoded by genomic sequence elements

Since the classical studies of Jacob and Monod in the early 1960s, it has been evident that genome sequences contain not only blueprints for genes and the proteins that they encode, but also the instructions for a coordinated regulatory program that governs when, where and to what extent these genes and proteins are expressed.

4 Aug 2015

SGI-DNA recognized by Frost & Sullivan for BioXp 3200 System

SGI-DNA, a Synthetic Genomics, Inc. company, was recently recognized by Frost & Sullivan for its groundbreaking innovation in genomic technologies for the BioXp 3200 System, an instrument with the capacity to simultaneously build 32 unique, double-stranded DNA fragments to study gene function, pathways, and whole genomes.

4 Aug 2015

California Initiative to Advance Precision Medicine selects two demonstration projects

Two demonstration projects that aim to yield quick results for patients have been selected by the new California Initiative to Advance Precision Medicine, a public-private effort launched by Governor Edmund G. Brown Jr.

4 Aug 2015

New study on photoaging could minimize risk of skin cancer

While all human organs undergo normal, chronological aging, human skin undergoes an additional type of aging because of its direct contact with the environment.

3 Aug 2015

Researchers uncover master regulators that govern the fate of TFH cells

Follicular helper Tcells (TFH cells), a rare type of immune cell that is essential for inducing a strong and lasting antibody response to viruses and other microbes, have garnered intense interest in recent years but the molecular signals that drive their differentiation had remained unclear.

31 Jul 2015

DFG Senate Commission approves recommendations for developing clinical research at German universities

At the annual meeting of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) on 30 June 2015, the Senate of the largest research funding organisation approved recommendations for "Developing Clinical Research at German Universities Between 2015 and 2025" (available in German).

30 Jul 2015

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes. The cause of this dysfunction has been unknown. Publishing online in Endocrinology, Buck Institute assistant research professor Akos Gerencser, PhD, shows that in patients with type 2 diabetes the balance between supply and demand of the mitochondrial membrane potential (ΔψM) is altered causing a decrease in the signaling that turns on insulin secretion.

30 Jul 2015

Bioinformatics News and Research

Further Reading

New NIH grants support research that combines DNA sequence information and electronic medical records

U-M study suggests potential treatment options for children with aggressive, advanced cancer

Autism Speaks launches web-based portal for MSSNG database

Researchers identify druggable target to potentially root out colon cancer, end relapse

Researchers uncover important cellular functions that help regulate inflammation

Analysis of toilet waste from international aircraft may lead to global surveillance of infectious diseases

New study uses donor sample to evaluate how self-identification measures intersect with genetics

Penn State College of Medicine students to work with medical educators to design new curriculum

Newly developed big data technique may have significant impact on health care

Researchers develop user-friendly platform for analyzing transcriptomic and epigenomic big data

Researchers create new cell screening method for immunotherapy cancer treatments

Study may lead to effective antimicrobial treatment strategies for people with uncontrolled diabetes

Discovery may lead to new ways to diagnose, treat brain cancer

Research: Critical aspects of human genome's regulatory program encoded by genomic sequence elements

SGI-DNA recognized by Frost & Sullivan for BioXp 3200 System

California Initiative to Advance Precision Medicine selects two demonstration projects

New study on photoaging could minimize risk of skin cancer

Researchers uncover master regulators that govern the fate of TFH cells

DFG Senate Commission approves recommendations for developing clinical research at German universities

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

Lab Diagnostics and Automation - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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