Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Non-invasive monitoring of glucose and adenosine monophosphate biomarkers in saliva

Blood tests are a common, yet often painful, step in health care. But what if we could skip the needles altogether? Saliva and blood contain many of the same biomarkers, and collecting spit is as simple as drooling into a container.

29 Nov 2023

Imaging approach provides objective evidence for the involvement of neck muscles in primary headaches

Researchers have identified objective evidence of how the neck muscles are involved in primary headaches, according to a study being presented today at the annual meeting of the Radiological Society of North America.

29 Nov 2023

Clinical trial reveals dapagliflozin's impact on heart failure and type 2 diabetes management

Researchers conducted a clinical trial on the effects of dapagliflozin on the urinary albumin-to-creatinine ratio (UACR) in patients with heart failure (HF) and type 2 diabetes mellitus (T2D).

29 Nov 2023

Dr Farid Khan, PharmaKure CEO, to speak on Alzheimer's diagnosis and treatment at Biotech Outsourcing Strategies Manchester 2023

Talk to focus on the spinout journey from drug repurposing to clinical trials for diagnosing and treating Alzheimer’s Disease.

28 Nov 2023

Towards a world free of tuberculosis: The ADVANCE-TB COST Action

Tuberculosis (TB) is caused by Mycobacterium tuberculosis. For decades, it has been among the top 10 reasons of death globally, and the number one infectious killer.

28 Nov 2023

Two kiwi fruit every day safe and can replace vitamin C supplementation

Study investigates the health effects of consuming two kiwifruits daily for six weeks. It finds no significant changes in metabolic and inflammatory biomarkers, indicating that regular kiwifruit consumption is safe and increases dietary vitamin C intake without adversely affecting metabolic health.

27 Nov 2023

Brain inflammation linked to neuropsychiatric symptoms in Alzheimer's

Common neuropsychiatric symptoms that doctors see in Alzheimer's disease patients originate from brain inflammation rather than amyloid and tau proteins, report University of Pittsburgh School of Medicine researchers today in JAMA Network Open.

27 Nov 2023

Researchers identify biomarkers for checkpoint inhibitor-induced hyperprogression of melanoma cells

Duke Cancer Institute researchers have identified potential biomarkers that predict the likelihood for checkpoint inhibitor drugs to backfire, driving hyper-progression of melanoma cells instead of unleashing the immune system to fight them.

24 Nov 2023

Saliva analysis breakthrough: Detecting cognitive decline stages in Parkinson’s patients

Researchers used integrative metaproteogenomic analysis to show that changes in salivary microbiota and biomolecules can indicate cognitive impairment stages in Parkinson’s disease patients, offering a potential diagnostic tool.

23 Nov 2023

Study shows how probiotic Bifidobacteria longum can help relieve constipation

Scientists have identified the genes in the probiotic Bifidobacteria longum responsible for improving gut motility.

21 Nov 2023

Novel urine-based prognostic model promises to transform bladder cancer treatment

In a study published in the journal Genes & Diseases, researchers from Fudan University, have developed a novel urine-based prognostic model that promises to transform the management and treatment of bladder cancer.

21 Nov 2023

Precision TMS approach yields improved outcomes for patients with major depressive symptoms

A new study from UCLA Health researchers demonstrates that a novel treatment is effective in most patients with major depressive symptoms even after multiple failed courses of antidepressant medication.

20 Nov 2023

Researchers develop machine learning-based tool for assessment of shoulder function

A study published in Scientific Reports introduces a simple string-pulling task as a reliable method for assessing shoulder mobility in both animals and humans. This innovative approach, combined with machine learning, has the potential to revolutionize the diagnosis and monitoring of shoulder injuries, offering an affordable and accessible solution.

19 Nov 2023

New insights into sporadic early-onset Alzheimer's disease

Alzheimer's disease (AD), the most prevalent neurodegenerative disease globally, poses a significant threat to human health.

17 Nov 2023

New study highlights urgent need for specific biomarkers in vascular cognitive impairment and dementia diagnosis

A review in Nature Reviews Neurology discusses the pathophysiological processes in vascular cognitive impairment and dementia (VCID), emphasizing the need for specific biomarkers to differentiate VCID from Alzheimer's disease and to improve diagnosis and treatment strategies, moving beyond reliance on neuroimaging and patient histories.

15 Nov 2023

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

A recent study in eClinicalMedicine found that fecal microbiota transplantation, combined with fruquintinib and tislelizumab, significantly improved survival rates in patients with microsatellite stable metastatic colorectal cancer, showing manageable safety and notable increases in progression-free and overall survival.

15 Nov 2023

Shrinkage in the brain's hippocampus area associated with cognitive decline

With the rise of new drugs that can target the amyloid-beta plaques in the brain that are an early sign of Alzheimer's disease, new ways are needed to determine whether memory loss and thinking problems are due to Alzheimer's disease or another neurodegenerative disorder.

15 Nov 2023

Biomarker News and Research

Further Reading

Non-invasive monitoring of glucose and adenosine monophosphate biomarkers in saliva

Imaging approach provides objective evidence for the involvement of neck muscles in primary headaches

Clinical trial reveals dapagliflozin's impact on heart failure and type 2 diabetes management

Dr Farid Khan, PharmaKure CEO, to speak on Alzheimer's diagnosis and treatment at Biotech Outsourcing Strategies Manchester 2023

Towards a world free of tuberculosis: The ADVANCE-TB COST Action

Two kiwi fruit every day safe and can replace vitamin C supplementation

Brain inflammation linked to neuropsychiatric symptoms in Alzheimer's

Researchers identify biomarkers for checkpoint inhibitor-induced hyperprogression of melanoma cells

Saliva analysis breakthrough: Detecting cognitive decline stages in Parkinson’s patients

Study shows how probiotic Bifidobacteria longum can help relieve constipation

Novel urine-based prognostic model promises to transform bladder cancer treatment

Precision TMS approach yields improved outcomes for patients with major depressive symptoms

Researchers develop machine learning-based tool for assessment of shoulder function

New insights into sporadic early-onset Alzheimer's disease

New study highlights urgent need for specific biomarkers in vascular cognitive impairment and dementia diagnosis

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

Shrinkage in the brain's hippocampus area associated with cognitive decline

UMass Lowell researchers study gut microbiome's connection to neurodegenerative diseases

RNA-based molecular subtypes can help predict response to chemotherapy in muscle-invasive bladder cancer

CVD-21: A novel instrument for predicting and monitoring cardiovascular disease

One Health, One Mission: The World Organisation for Animal Health on the AMR Frontline

Uniting Against Resistance: The World Health Organization for World Antimicrobial Awareness Week 2023

Tackling Antimicrobial Resistance: A Conversation with Dr. Beverley Isherwood

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