Birth Defects News and Research

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Macrolide, penicillin antibiotics in pregnancy could affect children’s health

A new study published in the journal BMJ in February 2020 reports that macrolide or penicillin antibiotic consumption in pregnancy could be linked to several adverse health outcomes in children. These include major malformations, cerebral palsy, attention deficit hyperactivity disorder, and autism spectrum disorder.

20 Feb 2020

Researchers uncover why Zika virus caused most harmful brain damage to Brazilian newborns

Due to Zika virus, more than 1,600 babies were born in Brazil with microcephaly, or abnormally small heads, from September 2015 through April 2016.

18 Feb 2020

Low folate levels associated with malnutrition in hospital patients

About 10% of patients who come to complex care hospitals may have low levels of folate and other indicators of malnutrition, investigators say.

18 Feb 2020

Slightly increased risk of death for babies conceived by IVF

A new study published in the journal Fertility and Sterility in February 2020 reports a higher risk for mortality in children who were conceived by the in vitro fertilization (IVF) technique followed by freezing of the embryos, compared to those naturally conceived, but only in the first few weeks of life.

18 Feb 2020

A broken heart for Valentine’s Day turns to healing

A broken heart for Valentine's Day sounds like the plot of a romantic comedy. But for Rebekah Holl, a literal broken heart was her reality on Feb. 14, 2019.

16 Feb 2020

Acid reflux drug may be a promising therapy to reduce preterm birth

Lansoprazole, an over-the-counter acid reflux drug that is often taken by pregnant women, may be a promising therapy to reduce preterm birth, according to a computational drug repurposing study that also tested several of the drugs in mice.

13 Feb 2020

Telemedicine can help pregnant women struggling with opioids

Sarah, a military veteran living on the coast of South Carolina, knew she had a problem. The opioids prescribed for her pain were becoming a headache of their own.

11 Feb 2020

New clinical trial to examine the safety of dapivirine vaginal ring and PrEP in pregnant women

The first clinical trial specifically designed to test the safety of the monthly dapivirine vaginal ring in pregnant women has begun in southern and eastern Africa.

10 Feb 2020

Natural antioxidant reverses reproductive harms caused by BPA exposure in worms

From plastics to pesticides, it seems like every week delivers fresh news about the dangers of endocrine disruptors--chemicals in the environment that alter the body's hormones and can lead to reproductive, developmental, neurologic and immune problems and cancer.

6 Feb 2020

Experimental vaccine could be effective against both Zika and Dengue

Walter Reed army institute of research has shown that a new vaccine against the Zika virus could be effective against both Zika and dengue virus. The study titled, “Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue experienced donor,” in the latest issue of the journal Nature Medicine.

3 Feb 2020

Routine Zika vaccination could help prevent suffering and save money

Global climate change has raised concerns that mosquito-borne diseases could become increasingly prevalent in the United States as warmer temperatures lead to increased mosquito activity.

23 Jan 2020

Study sheds new light on impact of common plasticizer on human reproductive health

Researchers at Harvard Medical School and the New York State Department of Health have discovered how a common plasticizer associated with human reproductive abnormalities likely does its damage at the molecular level.

10 Jan 2020

Scientists create 3D images of unique RNA molecule critical for stem cell programming

Scientists at Los Alamos and international partners have created the first 3-D images of a special type of RNA molecule that is critical for stem cell programming and known as the "dark matter" of the genome.

10 Jan 2020

Zika virus can affect infants despite ‘normal’ testing at birth

A study reports that infants born to Zika-exposed mothers showed neurodevelopmental slowing despite testing as normal at birth.

7 Jan 2020

Study underscores the importance of long-term follow-up for Zika-exposed infants

Colombian infants exposed to Zika virus in the womb showed neurodevelopmental delays as toddlers, despite having "normal" brain imaging and head circumference at birth, a finding that underscores the importance of long-term neurodevelopmental follow-up for Zika-exposed infants, according to a study published online Jan. 6, 2020, in JAMA Pediatrics.

6 Jan 2020

Exposure of pregnant women to persistent organic pollutants linked to smaller fetuses

Pregnant women exposed to persistent organic pollutants, or POPs, had slightly smaller fetuses than women who haven't been exposed to these chemicals, according to an analysis of ultrasound scans by researchers at the National Institutes of Health and other institutions.

30 Dec 2019

Scientists unveil how Zika virus replicates

The World Health Organization (WHO) declared the Zika virus infection a global threat during the peak of its outbreak in 2016. Since then, scientists and health experts raced to understand the virus better to develop novel and effective vaccines and treatments for the disease. Now, a team of researchers in China revealed how a protein in the virus reshapes its host to boost viral replication.

23 Dec 2019