Birth Defects News and Research

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New screening test can predict Down syndrome in first trimester

According to new research, an early blood test has proven to be an accurate predictor for Down syndrome.

13 Nov 2005

Scientists find key step in a signaling pathway that helps orchestrate embryonic development

The study, reported in Nature (Oct. 13, 2005), focuses on the Hedgehog family of signaling molecules, which play a central role in directing development of the early embryo's growth and spatial plan, as well as its later organ and limb development. Defects in Hedgehog signaling are a significant cause of some birth defects and cancers.

25 Oct 2005

Evidence is mounting to link toxoplasmosis with schizophrenia

Keep pet cats inside, stop feeding strays, cook meat sufficiently and reconsider the way the veterinary profession and public health agencies think - and teach - about the zoonotic pathogen Toxoplasma gondii.

18 Oct 2005

Isotretinoin-related birth defects

Isotretinoin (also known as Accutane) is a drug used to treat severe acne, but it can cause birth defects when taken by pregnant women. Because of these risks, the U.S. Food and Drug Administration and Roche Pharmaceuticals (Accutane's manufacturer) developed a voluntary pregnancy prevention program (PPP) in 1988 to try and prevent conception in women taking the drug.

16 Oct 2005

Tissue engineering used to reconstruct defective tracheas (windpipes) in fetal lambs

Researchers at Children's Hospital Boston report using tissue engineering to reconstruct defective tracheas (windpipes) in fetal lambs, first using cells from the amniotic fluid to grow sections of cartilage tube, and then implanting these living grafts into the lambs while still in the womb.

9 Oct 2005

High blood glucose levels early in pregnancy deprive the embryo of oxygen

The babies of women with diabetes are two to five times more likely to develop birth defects than offspring of women without the disease.

4 Oct 2005

Survey highlights the need to increase folic acid fortification of the grain supply

Only one-third of childbearing age women are taking a multivitamin containing the B vitamin folic acid daily to prevent serious birth defects of the brain and spine in their future babies, according to a decade of March of Dimes surveys.

3 Oct 2005

Folic acid levels should be double to provide maximum protection during pregnancy

Reports say that the U.S. government decision to add folic acid to enriched grain products has reduced the incidence of two devastating birth defects. but more needs to be done.

6 Sep 2005

Australian Medical Association highlights dangers of alcohol during pregnancy

Australian Medical Association President, Dr Mukesh Haikerwal, said recently that the National Health and Medical Research Council (NHMRC) should revise its guidelines on alcohol consumption during pregnancy.

6 Sep 2005

Folic acid fortification of grain foods has produced a one-third decline in serious birth defects of the brain and spine

...but the March of Dimes urged federal officials to help spare a greater number of babies from these devastating conditions by requiring higher levels of the B vitamin.

6 Sep 2005

Discovery of new gene FANCM sheds light on repair of damaged DNA

National Institute on Aging (NIA) researchers have discovered a new gene, FANCM, which sheds light on an important pathway involved in the repair of damaged DNA.

22 Aug 2005

Folates best at preventing Alzheimer's disease

According to results from a long-term study on aging, adults who eat the daily recommended allowance of folates significantly reduce their risk of developing Alzheimer's disease.

15 Aug 2005

FDA places very tight restrictions on acne drug Accutane

The U.S. Food and Drug Administration said late last week, that in future, patients and doctors will have to register with manufacturers and promise to comply with tight restrictions, before using the acne drug Accutane and it's generic versions.

14 Aug 2005

Vitamin B reduces risk of developing Alzheimer's disease

Adults who eat the daily recommended allowance of folates - B-vitamin nutrients found in oranges, legumes, leafy green vegetables and folic acid supplements - significantly reduce their risk of developing Alzheimer's disease, according to results from a long-term National Institute on Aging study of diet and brain aging.

13 Aug 2005

Low levels of folate linked to lower birth rates

Mothers-to-be with lower levels of the vitamin folate in their body during early pregnancy are more likely to have babies with lower, or less healthy, birth weights, a study has revealed.

4 Aug 2005

University of Florida researcher finds way to explore role of microRNAs in specific tissue

University of Florida researchers have learned how to selectively shut down a flyweight-sized genetic molecule that packs a heavyweight punch, a discovery that may help doctors better understand cancer, birth defects and other health problems.

20 Jul 2005

Fetal Alcohol Syndrome (FAS) occurs far more frequently than generally believed

Although estimates vary widely, when combined with the milder afflictions of Alcohol Related Birth Defects (ARBD) and several others, the Centers for Disease Control puts the frequency of FAS/ARBD as high as one in 100.

19 Jul 2005

Pomegranate juice may help babies resist brain injuries from low oxygen

Expectant mothers at risk of premature birth may want to consider drinking pomegranate juice to help their babies resist brain injuries from low oxygen and reduced blood flow, a new mouse study from Washington University School of Medicine in St. Louis suggests.

28 Jun 2005

Researchers discover new molecular mechanism that may allow for stem cell-based therapies to treat eye disorders such as retinal degeneration

The finding also reveals how the retina's own stem cells can be directed to aid the growth of new cells to replace diseased or dying ones in the eye. Study results appear in the June 24 issue of the journal Science.

27 Jun 2005

Folic acid improves memory and protects the brain from aging

According to scientists in Holland high doses of folic acid might help slow the cognitive decline of aging.

22 Jun 2005

Birth Defects News and Research

New screening test can predict Down syndrome in first trimester

Scientists find key step in a signaling pathway that helps orchestrate embryonic development

Evidence is mounting to link toxoplasmosis with schizophrenia

Isotretinoin-related birth defects

Tissue engineering used to reconstruct defective tracheas (windpipes) in fetal lambs

High blood glucose levels early in pregnancy deprive the embryo of oxygen

Survey highlights the need to increase folic acid fortification of the grain supply

Folic acid levels should be double to provide maximum protection during pregnancy

Australian Medical Association highlights dangers of alcohol during pregnancy

Folic acid fortification of grain foods has produced a one-third decline in serious birth defects of the brain and spine

Discovery of new gene FANCM sheds light on repair of damaged DNA

Folates best at preventing Alzheimer's disease

FDA places very tight restrictions on acne drug Accutane

Vitamin B reduces risk of developing Alzheimer's disease

Low levels of folate linked to lower birth rates

University of Florida researcher finds way to explore role of microRNAs in specific tissue

Fetal Alcohol Syndrome (FAS) occurs far more frequently than generally believed

Pomegranate juice may help babies resist brain injuries from low oxygen

Researchers discover new molecular mechanism that may allow for stem cell-based therapies to treat eye disorders such as retinal degeneration

Folic acid improves memory and protects the brain from aging

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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