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Only two per cent of 700 paediatric drug trials included independent safety checks

Only two per cent of paediatric drug trials reported that they had established independent safety monitoring committees that can help lead to the early detection of adverse drug reactions, according to a major review in the April issue of Acta Paediatrica.

19 Mar 2008

Most women unaware of uterine fibroid embolization

A study presented at the Society of Interventional Radiology's 33rd Annual Scientific Meeting shows of 105 patients in the Atlanta metro area, only 18 percent of the women who saw a private practice gynecologist were told about uterine fibroid embolization (UFE), a minimally invasive treatment for uterine fibroids provided by interventional radiologists.

19 Mar 2008

Long-term follow-up after percutaneous pulmonary radiofrequency ablation

Radiofrequency ablation (RFA) - an interventional treatment that "cooks" and kills lung cancer tumors with heat - greatly improves survival time from primary or metastatic inoperable lung tumors, according to a study released at the Society of Interventional Radiology's 33rd Annual Scientific Meeting.

18 Mar 2008

Scientists identify potential therapy targets for schistosomiasis

A research team supported by the National Institutes of Health (NIH) Roadmap and the National Institute of Allergy and Infectious Diseases (NIAID) has identified chemical compounds that hold promise as potential therapies for schistosomiasis, a parasitic disease that afflicts more than 200 million people worldwide.

18 Mar 2008

Chikungunya virus appears seldom to harm infants of mothers infected early in pregnancy

Chikungunya virus, an infectious agent transmitted by mosquitoes, appears seldom to harm infants of mothers infected early in pregnancy, but can frequently cause serious problems, including lasting brain injury, in babies born to mothers who acquire the virus near the time of delivery, according to a study in PLoS Medicine.

18 Mar 2008

Discovery of chemical compounds that hold promise as potential therapies for schistosomiasis

17 Mar 2008

A new finding in liver transplantation and antifibrinolytics?

Orthotopic liver transplantation (OLT) is associated with severe bleeding and considerable transfusion requirements.

14 Mar 2008

Post-stroke clot-busting therapy beneficial for patients on aspirin

Patients given a clot-busting drug following stroke appear to have better outcomes if they were already taking anti-platelet medications, despite an apparent increased risk for bleeding in the brain, according to an article posted online that will appear in the May 2008 print issue of Archives of Neurology.

11 Mar 2008

Long-term effects of synthetic progestins cause for concern

The widely used synthetic progestin medroxyprogesterone acetate (MPA) decreased endothelial function in premenopausal women in a study done at the University of Oregon.

11 Mar 2008

Magnesium linked to lower risk for some strokes in male smokers

Male smokers who consume more magnesium appear to have a lower risk for cerebral infarction, a type of stroke that occurs when blood flow to the brain is blocked, according to a report in the March 10 issue of Archives of Internal Medicine.

11 Mar 2008

Femara helps protect against return of breast cancer after completing Tamoxifen therapy

Women may reduce the risk of their breast cancer returning by starting treatment with Femara (letrozole tablets) anywhere from one to seven years after finishing tamoxifen therapy, according to a new analysis published in the Journal of Clinical Oncology.

11 Mar 2008

Fugitive cancer cells can be blocked by stopping blood cells that aid them

Cancer cells get a helping hand from platelets, specialized blood cells involved in clotting.

10 Mar 2008

Aspirin reduces the risk of breast cancer

According to a new British report, taking drugs such as Aspirin can reduce the risk of breast cancer by as much as 20 percent.

10 Mar 2008

Guidelines for von Willebrand disease diagnosis and management

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health today issued the first clinical guidelines in the United States for the diagnosis and management of von Willebrand Disease (VWD), the most common inherited bleeding disorder.

4 Mar 2008

New guidelines for von Willebrand disease

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, has issued the first clinical guidelines in the United States for the diagnosis and management of von Willebrand Disease (VWD), the most common inherited bleeding disorder.

1 Mar 2008

Ginkgo biloba and dementia

Taking the supplement ginkgo biloba had no clear-cut benefit on the risk of developing memory problems, according to a study published in the February 27, 2008, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Feb 2008

Risks of CVD for COX-2 inhibitors lower than previously reported

In an article published in the March issue of the Journal of Cardiovascular Pharmacology and Therapeutics, researchers from Florida Atlantic University (FAU) assess the totality of evidence, including strengths and limitations of different types of evidence contributing to the debate about cardiovascular disease (CVD) risks of cyclooxygenase-2 (COX-2) inhibitors and non-steroidal anti-inflammatory drugs (NSAIDs).

27 Feb 2008