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Study strengthens link between HHV-6B and mesial temporal lobe epilepsy

A ten-year NIH-funded study has determined that a third of infants with prolonged seizures and fever suffer from either a new or reactivated roseola virus infection. Roseola viruses are the cause of the common childhood rash, but can also cause limbic encephalitis, a condition that frequently progresses to epilepsy. Investigators discovered one of the roseola viruses, human herpesvirus-6B (HHV-6B) in the blood of 32% of 169 infants with prolonged seizures, a condition known as status epilepticus.

15 Jun 2012

Exposure to BPA during gestation has long-lasting, trans-generational effects

Exposure to low doses of Bisphenol A (BPA) during gestation had immediate and long-lasting, trans-generational effects on the brain and social behaviors in mice, according to a recent study accepted for publication in the journal Endocrinology, a publication of The Endocrine Society.

15 Jun 2012

High-efficiency oxygen inhaler from Dehaier

Dehaier Medical Systems Ltd., an emerging leader in the development, assembly, marketing and sale of medical devices and homecare medical products in China, today announced that the Company has co-developed its "High-Efficiency Oxygen Inhaler" with Dr. Ding Jianzhang of Beijing Haidian Hospital, which is expected to begin selling in the third quarter of 2012 in mainland China.

15 Jun 2012

Dietitians now have access to simple genetic test kit from Nutrigenomix

The one-size-fits-all approach to nutritional counselling includes basic advice to eat more whole grains and cut back on sodium. While this guidance is certainly appropriate, it doesn't take into account that these universal nutrition recommendations are not equally useful for every person.

15 Jun 2012

FDA approves Menhibrix for vaccination against meningococcal and Hib diseases

The U.S. Food and Drug Administration today approved Menhibrix, a combination vaccine for infants and children ages 6 weeks through 18 months, for prevention of invasive disease caused by Neisseria meningitidis serogroups C and Yand Haemophilus influenzae type b.

15 Jun 2012

Minimally invasive procedure to treat high blood pressure

A radically different approach to treating high blood pressure – using a minimally invasive procedure – is being evaluated as part of a Pivotal Phase III 90-site national trial that includes The Carl H. and Edyth Lindner Center for Research and Education at The Christ Hospital.

14 Jun 2012

Oxidative stress linked to NSS severity in schizophrenia

The severity of neurologic soft signs negatively correlates with antioxidant superoxide dismutase activity in patients with schizophrenia, research shows.

14 Jun 2012

Dark chocolate cuts CV risk in metabolic syndrome

Eating dark chocolate on a daily basis appears to decrease risk for cardiovascular events in patients with the metabolic syndrome, say researchers.

14 Jun 2012

$Single-leg approach safe and effective for children with hip and thigh fractures$

Single-leg approach safe and effective for children with hip and thigh fractures

Challenging a longstanding practice of casting both legs in children with hip and thigh fractures, a new Johns Hopkins Children's Center study shows that such fractures heal just as well in single-leg casts, while giving children greater comfort and mobility.

14 Jun 2012

ABL to perform process development and cGMP manufacturing of recombinant scuPA

Advanced BioScience Laboratories, Inc. (ABL) will perform process development and cGMP manufacturing of recombinant scuPA, an enzyme therapy candidate for patients with pleural loculation or scarring surrounding the lung.

14 Jun 2012

Alpha-myosin triggers development of autoimmunity after heart attack

After people with type 1 diabetes have a heart attack, their long-term chance of suffering even more heart damage skyrockets. But the reason has long puzzled scientists. Now researchers at Joslin Diabetes Center have identified the misstep that sparks this runaway chronic damage and a promising way to block it.

14 Jun 2012

AB Science announces results from masitinib phase 2 study on MS

AB Science SA, a pharmaceutical company specializing in the research, development and commercialization of protein kinase inhibitors, announces the publication of results from the human phase 2 study of masitinib carried-out in the treatment of progressive multiple sclerosis.

14 Jun 2012

Research into alcohol's effect on juvenile rats

Research into alcohol's effect on juvenile rats shows they have an ability to build up a physical, but not cognitive, tolerance over the short term - a finding that could have implications for adolescent humans, according to Baylor University psychologists.

14 Jun 2012

Reovirus can trick the body's defenses to reach and kill cancer cells

Scientists have shown how a promising viral therapy that delivers a double blow to cancer can sneak up on tumors undetected by hitching a ride on blood cells.

14 Jun 2012

Cancers often recur after treatment with single drugs that “target” tumor cells’ genetic pathways

Targeted cancer cell therapies using man-made proteins dramatically shrink many tumors in the first few months of treatment, but new research from Johns Hopkins scientists finds why the cells all too often become resistant, the treatment stops working, and the disease returns.

14 Jun 2012

New analogues effective in inhibiting NOS activity in Parkinson models

University of Granada researchers have tested melatonin analogues in rats as it inhibits the enzyme nitric oxide synthase (NOS), which is involved in the development of conditions as inflammatory bowel disease, septic shock or rheumatoid arthritis, as well as in neurodegenerative conditions as Huntington's disease, Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.

14 Jun 2012

Hysterectomy may increase risk of cardiovascular disease in postmenopausal women

Estrogen-deficient, postmenopausal women who have had their uterus removed appear to have stiffer arteries compared to similar women who have not had a hysterectomy, according to new research from the University of Colorado School of Medicine.

14 Jun 2012

Violence affects a child's quality and quantity of sleep

When violence shatters a child's world, the torment can continue into their sleep, according to researchers in Cleveland. The impact is measurable and affected by the severity of the violence, and the effects can last over time.

14 Jun 2012

Researchers use brain imaging to uncover susceptibility to psychological stress and trauma

Most people have intense emotional reactions to traumatizing events like road accidents or combat. But some suffer far longer, caught in the grip of long-term debilitating disorders such as Post-Traumatic Stress Disorder (PTSD). Because doctors cannot predict who will develop these disorders, however, early or preventive intervention is not available. Now, a new project led by researchers at Tel Aviv University seeks to identify pre-traumatic subjects - those who are more susceptible to long-standing disorders if exposed to a traumatic incident.

14 Jun 2012

Mixed picture for pulse pressure effect on surgical outcomes

Two studies published in Anesthesia and Analgesia have muddied the water regarding the effect of preoperative pulse pressure on perioperative outcomes.

13 Jun 2012