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New device to treat heart hiccups

"It took off to about 160 beats per minute and then dropped to 50. It seemed confused. Then it went back to normal," recalled Tsuji, 47, an avid cyclist, of that day in 2003. "I didn't notice any symptoms at that point, so I blew it off. I figured there was something wrong with it."

3 Feb 2011

NIST team demonstrates a method for controlling different-sized nanoparticle production

The same properties that make engineered nanoparticles attractive for numerous applications-small as a virus, biologically and environmentally stabile, and water-soluble-also cause concern about their long-term impacts on environmental health and safety.

3 Feb 2011

American Society of Nephrology supports US Dietary Guidelines for Americans 2010

The American Society of Nephrology (ASN) supports the recommendations, which include advising Americans to reduce their daily salt intake. The recommendations encourage nearly half of Americans to drastically reduce their salt intake.

3 Feb 2011

First therapeutic vaccine designed from dendritic cells of patient achieves significant response

The therapeutic vaccines are a priority research line of the HIVACAT, the catalan programme for the development of therapeutic vaccines and prevention against the Human Immunodeficiency Virus (HIV). This type of therapeutic vaccine helps the patients who are carriers of the virus, combat infection and control the appearance of AIDS in the same way as with the current antiretroviral treatments.

3 Feb 2011

Generic drugs to treat hypertension, heart failure could help NHS save £200 million

Using a generic drug to treat hypertension and heart failure, instead of branded medicines from the same class, could save the UK National Health Service (NHS) at least £200 million in 2011 without any real reduction in clinical benefits.

3 Feb 2011

Lead exposure can lead to high blood pressure in pregnant women: Study

Even minute amounts of lead may take a toll on pregnant women, according to a study published by Lynn Goldman, M.D., M.S., M.P.H., Dean of George Washington University's School of Public Health and Health Services in D.C., and colleagues, in the journal Environmental Health Perspectives.

3 Feb 2011

Losartan improves effectiveness of nanotherapeutics against cancer

Low doses of an inexpensive, FDA-approved hypertension medication may improve the results of nanotherapeutic approaches to cancer treatment. In a report in the early edition of Proceedings of the National Academy of Sciences, Massachusetts General Hospital (MGH) investigators describe experiments showing that the generic drug losartan, by modifying the network of collagen fibers that characterizes most solid tumors, improved the effectiveness of two nanotherapeutics against several types of cancer.

3 Feb 2011

Researchers to develop new diagnostics platform for early detection of lung cancer

The earlier cancers can be detected, the better the chances of a cure. Researchers are now working to develop a new diagnostics platform with which the illness can be diagnosed in its early stages, even during a visit to the general practitioner: protein biomarkers in exhaled air divulge the presence of pathological cells in the lung.

3 Feb 2011

International scientist team identifies gene mutation strongly linked to schizophrenia

In a major advance for schizophrenia research, an international team of scientists, led by Jonathan Sebat, PhD, assistant professor of psychiatry and cellular and molecular medicine at the University of California, San Diego School of Medicine, has identified a gene mutation strongly linked to the brain disorder - and a signaling pathway that may be treatable with existing compounds.

3 Feb 2011

New replacement valve can help patients to avoid multiple open-heart surgeries

Congenital heart defects are the most common type of major birth defects in the U.S., affecting about 34,000 babies each year. Twenty percent of these patients are born with a malformation of the pulmonary valve, which is a flap-like opening on the right side of the heart that is responsible for regulating the blood flow to the lungs. Now, a new replacement valve being used at Rush University Medical Center can help patients with damaged heart valves delay or avoid multiple open-heart surgeries.

3 Feb 2011

Researchers design nanoparticles that make blood clots visible to CT scanner

For almost two decades, cardiologists have searched for ways to see dangerous blood clots before they cause heart attacks. Now, researchers at Washington University School of Medicine in St. Louis report that they have designed nanoparticles that find clots and make them visible to a new kind of X-ray technology.

3 Feb 2011

Enrollment stopped in one of two global necitumumab Phase III studies in NSCLC

Eli Lilly and Company and Bristol-Myers Squibb Company announced today that they have stopped enrollment in one of their two global Phase III studies evaluating necitumumab, an investigational anti-cancer agent, as a first-line treatment for advanced non-small cell lung cancer (NSCLC).

3 Feb 2011

Vegetarians, vegans need to increase omega-3 fatty acids and vitamin B12 to reduce heart disease risk

People who follow a vegan lifestyle - strict vegetarians who try to eat no meat or animal products of any kind - may increase their risk of developing blood clots and atherosclerosis or "hardening of the arteries," which are conditions that can lead to heart attacks and stroke. That's the conclusion of a review of dozens of articles published on the biochemistry of vegetarianism during the past 30 years.

3 Feb 2011

Older people with metabolic syndrome may face high risk of developing memory loss

Older people with larger waistlines, high blood pressure and other risk factors that make up metabolic syndrome may be at a higher risk for memory loss, according to a study published in the February 2, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

3 Feb 2011

EGEN receives 4-year, $1.6M FDA grant for EGEN-001 Phase II clinical study in ovarian cancer

EGEN, Inc. today announced that the Food and Drug Administration (FDA) has awarded the company a four-year grant of $1,600,000 to assist in the Phase II clinical development of EGEN-001, the company's lead product. EGEN-001 is under clinical development for the treatment of advanced recurrent ovarian cancer.

2 Feb 2011

Isis commences ISIS-FXIRx Phase 1 study for treatment of clotting disorders

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 1 study of ISIS-FXIRx, an antisense drug designed to treat clotting disorders. ISIS-FXIRx inhibits the production of Factor XI, a clotting factor that is an important component of the coagulation pathway. Because of its role in the intrinsic coagulation pathway, inhibition of Factor XI could offer an effective approach for preventing the formation of blood clots with a lower risk of bleeding.

2 Feb 2011

Innovative diabetes management concept can significantly reduce HbA1c values, improve glycemic control

An innovative diabetes management concept including structured self-monitoring of blood glucose (SMBG), data visualization, pattern analysis and derived therapy adjustments can significantly reduce HbA1c values, improve glycemic control and enhance patients' quality of life. These are the key findings of the 12-month data from the Structured Testing Protocol (STeP) Study, newly published in Diabetes Care.

2 Feb 2011

New study examines role of later acquisition of hepatitis C in HIV patients

Hepatitis C is a leading cause of illness and death for individuals infected with both HIV and hepatitis C. Recent reports from around the world demonstrate that hepatitis C is emerging as a sexually transmitted infection among HIV-infected men who do not inject drugs. However, many HIV-infected men do not receive continued screening for hepatitis C throughout their HIV care.

2 Feb 2011

Targeted delivery combination crosses brain protecting barrier and homes in on tumors

A targeted delivery combination selectively crosses the tight barrier that protects the brain from the bloodstream to home in on and bind to brain tumors, a research team led by scientists from The University of Texas MD Anderson Cancer Center reported in the January issue of the Journal of Clinical Investigation.

2 Feb 2011

Nitrate boosts efficiency of mitochondria

The spinach-eating cartoon character Popeye has much to teach us, new research from the Swedish medical university Karolinska Institutet shows. The muscles' cellular power plants - the mitochondria - are boosted by nitrate, a substance found in abundance in vegetables such as lettuce, spinach and beetroot.

2 Feb 2011

Blood News and Research

New device to treat heart hiccups

NIST team demonstrates a method for controlling different-sized nanoparticle production

American Society of Nephrology supports US Dietary Guidelines for Americans 2010

First therapeutic vaccine designed from dendritic cells of patient achieves significant response

Generic drugs to treat hypertension, heart failure could help NHS save £200 million

Lead exposure can lead to high blood pressure in pregnant women: Study

Losartan improves effectiveness of nanotherapeutics against cancer

Researchers to develop new diagnostics platform for early detection of lung cancer

International scientist team identifies gene mutation strongly linked to schizophrenia

New replacement valve can help patients to avoid multiple open-heart surgeries

Researchers design nanoparticles that make blood clots visible to CT scanner

Enrollment stopped in one of two global necitumumab Phase III studies in NSCLC

Vegetarians, vegans need to increase omega-3 fatty acids and vitamin B12 to reduce heart disease risk

Older people with metabolic syndrome may face high risk of developing memory loss

EGEN receives 4-year, $1.6M FDA grant for EGEN-001 Phase II clinical study in ovarian cancer

Isis commences ISIS-FXIRx Phase 1 study for treatment of clotting disorders

Innovative diabetes management concept can significantly reduce HbA1c values, improve glycemic control

New study examines role of later acquisition of hepatitis C in HIV patients

Targeted delivery combination crosses brain protecting barrier and homes in on tumors

Nitrate boosts efficiency of mitochondria

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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