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Early HAART during TB treatment prolongs survival of untreated HIV-infected adults: CAMELIA study

A clinical trial in Cambodia has found it possible to prolong the survival of untreated HIV-infected adults with very weak immune systems and newly diagnosed tuberculosis (TB) by starting anti-HIV therapy two weeks after beginning TB treatment, rather than waiting eight weeks, as has been standard.

23 Jul 2010

African Americans at increased risk of kidney failure caused by hypertension

Regardless of demographics, African American patients with hypertensive nephrosclerosis have a higher rate of developing end stage renal disease than dying prematurely, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.Earlier studies showed patients of all races with Chronic Kidney Disease were at greater risk of dying prematurely from cardiovascular disease than reaching ESRD.

23 Jul 2010

Discontinuing epoetin can normalize hemoglobin levels in hemodialysis patients

Discontinuing the anemia drug epoetin may be more effective than reducing the dose for normalizing potentially dangerous high hemoglobin levels in hemodialysis patients, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology. The results provide useful information about the balance required between administering epoetin and achieving target hemoglobin levels.

23 Jul 2010

ASH to honor six scientists for treatment of hematologic diseases

The American Society of Hematology (ASH), the world's largest professional society of blood specialists, will honor six scientists who have made significant contributions to the understanding and treatment of hematologic diseases. These awards will be presented at the 52nd ASH Annual Meeting taking place December 4-7 in Orlando.

23 Jul 2010

Cytrx’s tamibarotene achieves molecular complete remission in advanced acute promyelocytic leukemia

CytRx Corporation, a biopharmaceutical company specializing in oncology, today announced that a 44-year-old female patient with advanced acute promyelocytic leukemia (APL) achieved molecular complete remission with no evidence of disease in the blood cells and/or bone marrow following treatment with CytRx's oncology drug candidate tamibarotene.

23 Jul 2010

Utah Medical Products second-quarter international sales increase 10%

In the second calendar quarter (2Q) and first half (1H) of 2010, Utah Medical Products, Inc.'s changes in financial results compared to the same time period in the prior calendar year were as follows

23 Jul 2010

New drug to treat chronic pain in SCD patients

A University of Minnesota Medical School research team led by Kalpna Gupta, Ph.D., has discovered that cannibinoids offer a novel approach to ease the chronic and acute pain caused by sickle cell disease.Using a mouse model of SCD, Gupta and University of Minnesota colleagues studied the pain mechanisms by observing animals that exhibited both musculoskeletal pain and temperature sensitivity, symptoms similarly experienced by humans with SCD. The team compared two classifications of drugs in their ability to manage pain sensed by the animals, the traditionally prescribed classification of drugs, opioids, with a new therapeutic approach, cannabinoids, a synthetic compound based on marijuana derivatives. Currently, the only approved treatment for management of severe pain in SCD is opioids.

23 Jul 2010

Study reveals link between allergies, asthma and old age

Mistaken for illnesses like bronchitis and emphysema, exacerbated by medications like aspirin, and overlooked by patients and doctors alike, asthma is a common and highly treatable condition in older adults. And while allergies tend to decrease with age, they also are frequently disregarded as a potential cause of misery for the elderly.

23 Jul 2010

Osteocalcin hormone can regulate glucose levels: Research

Researchers led by Columbia University Medical Center have discovered that the skeleton plays an important role in regulating blood sugar and have further illuminated how bone controls this process. The finding, published in Cell, is important because it may lead to more targeted drugs for type 2 diabetes.

23 Jul 2010

AIDS 2010 studies, releases: Criminalization, discrimination of high-risk groups; Test-and-treat; UNAIDS launches HIV prevention commission

The criminalization of men who have sex with men (MSM) and transgender people in Asia is holding back efforts to contain HIV/AIDS in the region, according to a report presented Wednesday by the U.N. Development Program (UNDP) and Asia Pacific Coalition on Male Sexual Health at the International AIDS Conference-AIDS 2010, VOA News reports. The report "linked the criminalization of homosexual behavior to an increase in the infection rate of HIV and AIDS in Asia," the news service writes (Dewan, 7/21).

23 Jul 2010

Gene expression profiling may provide molecular diagnostic tool to diagnose depression

Blood tests have been extremely important tools aiding doctors in making medical diagnoses and in guiding the treatment of many diseases. However, psychiatry is one area of medicine where there are few diagnostic blood tests.New scientific fields may someday generate blood tests that can be used for these purposes. Some of the areas under increasingly intensive study are genetics, the study of variations in the genes that can be extracted from blood cells, and genomics like proteomics, the measurement of the levels of specific proteins in the blood, and gene expression profiling, which measures the levels of RNA produced from DNA as an indication of the level of the "activity" of particular genes.

23 Jul 2010

Three toxins in food identified as triggers to gluten intolerance: study

Coeliac disease cause by intolerance to gluten present in food and drinks like bread, pasta, cereals, biscuits and beer commonly affects many people all over the world. This affects 1 percent of all people in UK, especially women. Patients are advised to stay away from gluten to prevent damage to their intestines. In spite of this in five years most patients develop problems in their intestines. A gluten free diet is also difficult to maintain. Possible symptoms include diarrhoea, nausea and vomiting, recurrent stomach pain, tiredness, headaches, weight loss and mouth ulcers. These may be mild, moderate or severe in different individuals.

22 Jul 2010

Agfa HealthCare's IMPAX HeartStation enables rapid diagnosis of 15-lead ECG studies when compared to 12-lead ECG studies at Western Maryland Regional Medical Center

Agfa HealthCare, a leading provider of diagnostic imaging and healthcare IT solutions, today announces that Western Maryland Regional Medical Center's recent upgrade to the newest version of IMPAX HeartStation ECG Management System has helped enable the rapid diagnosis and treatment of patients with posterior wall heart attacks. The Cumberland-based hospital is using the recently released features of IMPAX HeartStation to digitally review and archive 15-lead ECG studies.

22 Jul 2010

Bristol-Myers Squibb second-quarter net sales increase 2% to $4.8 billion

Bristol-Myers Squibb Company today reported results for the second quarter of 2010 which featured data on key marketed and investigational compounds in its oncology, diabetes and cardiovascular franchises, and growth in sales and EPS. The company also confirmed guidance for 2010 and minimum guidance for non-GAAP EPS in 2013.

22 Jul 2010

Tarsa completes enrollment in Phase III ORACAL trial for postmenopausal osteoporosis

Tarsa Therapeutics, Inc. today announced progress in the ORACAL trial of its oral calcitonin product for the treatment of postmenopausal osteoporosis. The company has completed patient enrollment in this multinational, randomized, double-blind, placebo-controlled Phase III trial designed to enroll approximately 550 patients. In addition, Tarsa announced that the independent Data Monitoring Committee (DMC) for the ORACAL trial has completed two separate safety reviews of patient data and recommended that the trial proceed as planned.

22 Jul 2010

Alexion second-quarter non-GAAP net income increases 56% to $36.9 million

Alexion Pharmaceuticals, Inc. today announced financial results for the three and six months ended June 30, 2010.

22 Jul 2010

Study reveals link between anti-TPO antibodies and placental abruption

Pregnant women with antibodies that can indicate early thyroid disease are three times as likely to have placental separation during labor, researchers at UT Southwestern Medical Center have found in a study of more than 17,000 women.

22 Jul 2010

Strong feelings alter one's ability to resist temptations: Study

While it may be convenient to add in a trip to the grocery store after a good workout at the gym, a recent study confirms it may not be the best idea for your waistline.The study in the current issue of the Journal of Consumer Research indicates mood, positive or negative, has a noticeable effect on the choices made by consumers. Co-authors Alexander Fedorikhin, of Indiana University's Kelley School of Business Indianapolis, and Vanessa Patrick, of the University of Houston, conducted three experiments to show how strong feelings alter one's ability to resist temptations.

22 Jul 2010

Predator-released chemicals function as warning signals for egg-laying mosquitoes

A scientific breakthrough might assist in the fight against mosquitoes. New research carried out at the University of Haifa in collaboration with researchers from other universities has chemically identified, for the first time, compounds released by mosquitoes' natural aquatic predators that function as warning signals for egg laying mosquitoes. Introducing these natural chemicals into mosquito breeding sites will cause the mosquitoes to sense risk of predation to their progeny and avoid laying their eggs there.

22 Jul 2010

Genomics researchers study role of protein in metabolic disorders, heart disease

Studying a protein already known to play an important role in type 2 diabetes and cancer, genomics researchers have discovered that it may have an even broader role in disease, particularly in other metabolic disorders and heart disease. In finding unsuspected links to other disease-related genes, the scientists may have identified future targets for drug treatments.

22 Jul 2010

Blood News and Research

Early HAART during TB treatment prolongs survival of untreated HIV-infected adults: CAMELIA study

African Americans at increased risk of kidney failure caused by hypertension

Discontinuing epoetin can normalize hemoglobin levels in hemodialysis patients

ASH to honor six scientists for treatment of hematologic diseases

Cytrx’s tamibarotene achieves molecular complete remission in advanced acute promyelocytic leukemia

Utah Medical Products second-quarter international sales increase 10%

New drug to treat chronic pain in SCD patients

Study reveals link between allergies, asthma and old age

Osteocalcin hormone can regulate glucose levels: Research

AIDS 2010 studies, releases: Criminalization, discrimination of high-risk groups; Test-and-treat; UNAIDS launches HIV prevention commission

Gene expression profiling may provide molecular diagnostic tool to diagnose depression

Three toxins in food identified as triggers to gluten intolerance: study

Agfa HealthCare's IMPAX HeartStation enables rapid diagnosis of 15-lead ECG studies when compared to 12-lead ECG studies at Western Maryland Regional Medical Center

Bristol-Myers Squibb second-quarter net sales increase 2% to $4.8 billion

Tarsa completes enrollment in Phase III ORACAL trial for postmenopausal osteoporosis

Alexion second-quarter non-GAAP net income increases 56% to $36.9 million

Study reveals link between anti-TPO antibodies and placental abruption

Strong feelings alter one's ability to resist temptations: Study

Predator-released chemicals function as warning signals for egg-laying mosquitoes

Genomics researchers study role of protein in metabolic disorders, heart disease

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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