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Onyx Pharmaceuticals acquires license option on novel JAK2 inhibitors from S*BIO

Onyx Pharmaceuticals, Inc. has announced that it has acquired an option to license rights to SB1518, an orally available, potent, and selective inhibitor of Janus Kinase 2 (JAK2), and SB1578, also a JAK2 inhibitor, from S*BIO Pte Ltd based in Singapore.

6 Jan 2009

Chimerix completes phase I study and starts phase II multi-dose trial for CMX001

Chimerix, Inc., a biotechnology company developing orally available antiviral therapeutics, has announced that the Company has completed a single and multi-dose Phase I study of CMX001 in healthy volunteers.

6 Jan 2009

Researchers gain new insight into cancer metastasis

Few things are as tiresome as house hunting and moving. Unfortunately, metastatic cancer cells have the relocation process down pat. Tripping nimbly from one abode to another, these migrating cancer cells often prove far more deadly than the original tumor.

5 Jan 2009

Metadherin gene plays dual role in breast cancers with poor prognosis

A new study reveals that the metadherin gene (MTDH) plays a role in both cancer metastasis and resistance to chemotherapy.

5 Jan 2009

Why hip replacements fail

Each year thousands of patients undergo total hip replacement surgery in order to help alleviate pain associated with debilitating hip disease and other related hip problems.

5 Jan 2009

Parkinson's increases risk for orthopaedic conditions

Although Parkinson's disease (PD) is a neurological disorder, according to an article in the January 2009 issue of the Journal of the American Academy of Orthopaedic Surgeons, the disease also increases a person's risk of experiencing complicated orthopaedic conditions.

5 Jan 2009

MRI scans emerge as vital resource in treatment of back pain

Magnetic resonance imaging (MRI) is a growing technology providing an increasing number of clinical benefits when used in the evaluation of back pain according to an article in the January 2009 issue of the Journal of the American Academy of Orthopaedic Surgeons.

5 Jan 2009

Total hip replacement surgery

Each year thousands of patients undergo total hip replacement surgery in order to help alleviate pain associated with debilitating hip disease and other related hip problems.

1 Jan 2009

Magnetic resonance imaging emerges as vital resource in back pain treatment

1 Jan 2009

Oral bisphosphonates linked to increased jaw necrosis

Researchers at the University Of Southern California, School Of Dentistry release results of clinical data that links oral bisphosphonates to increased jaw necrosis

1 Jan 2009

Cost effectiveness of spinal surgery examined

Back pain affects more than 80 percent of people and costs more than $100 billion annually in the U.S. But is the surgery cost effective?

30 Dec 2008

How to enhance non-thermal effects of ultrasound

In recent years HIFU has been widely used for the treatment of solid tumors, such as liver tumor, bone tumor, and breast cancer.

30 Dec 2008

Gardening a great way for seniors to stay healthy

The Centers for Disease Control and Prevention and the American College of Sports Medicine recommends at least 30 minutes of moderate-intensity physical activity on most days of the week in order to maintain and improve optimal health.

30 Dec 2008

New therapy for transplant rejection

Researchers in the U.S. have discovered a new cancer drug which effectively treats transplant rejections.

29 Dec 2008

Physicians perform rare surgery to restore hearing to a deaf patient

Marisela Leon, 44, has neurofibromatosis type 2 -- a rare genetic condition that causes tumors to grow on nerves in the brain or spinal cord, but most commonly on the auditory nerve. Leon lost her hearing more than four years ago when surgery to remove a tumor damaged her auditory nerve.

22 Dec 2008

Stem cells and leukemia battle for marrow microenvironment

Learning how leukemia takes over privileged "niches" within the bone marrow is helping researchers develop treatment strategies that could protect healthy blood-forming stem cells and improve the outcomes of bone marrow transplantation for leukemia and other types of cancer.

18 Dec 2008

FDA approves Mozobil (plerixafor) for multiple myeloma or non-Hodgkin's lymphomas

The U.S. Food and Drug Administration has approved Mozobil (plerixafor), a drug that helps increase the number of blood stem cells for bone marrow transplantation in patients with certain forms of blood cancer.

18 Dec 2008

Trial tests adult stems cells to treat congestive heart failure

The University of California, San Diego Medical Center is the first hospital in California to enroll patients in a multi-center clinical trial, sponsored by Angioblast Systems Inc., to examine the safety and feasibility of administering adult stems cells to treat congestive heart failure.

18 Dec 2008

Research highlights recognized disease risks associated with vitamin D deficiency

Once believed to be important only for bone health, vitamin D is now seen as having a critical function in maintaining the immune system throughout life.

17 Dec 2008

New bone and tissue regeneration technique

Using stem cell lines not typically combined, researchers at Columbia University Medical Center have designed a new way to "grow" bone and other tissues.

15 Dec 2008