Bone News and Research

RSS

75% of hospital patients suffer from malnutrition regardless of their pathology

A study of 817 patients conducted in the Department of Nutrition and Bromatology at the University of Granada (UGR), in collaboration with the Unit of Nutrition and Dietetics at the hospital Virgen de las Nieves (Granada, Spain) of 817 patients, showed that 75% of hospitalised patients suffer from malnutrition regardless of their pathology.

24 Oct 2007

Charcot foot becoming more common

Charcot foot is a sudden softening of the foot's bones caused by severe neuropathy, or nerve damage, a common diabetic foot complication. It can trigger an avalanche of problems, including joint loss, fractures, collapse of the arch, massive deformity, ulcers, amputation, and even death. As the disorder progresses, the bottom of the foot can become convex, bulging like the hull of a ship.

24 Oct 2007

Potent inhibitor of Kinesin CENP-E demonstrates tumor cell inhibition

A first-in-class, targeted investigational therapy specifically designed to inhibit a single protein that functions only during cell division shows potent activity in a broad range of cancer cell lines, say researchers from GlaxoSmithKline.

24 Oct 2007

Experimental cancer pharmaceuticals under trial

A potent and selective inhibitor of the mitotic kinesin CENP-E (GSK923295A) demonstrates a novel mechanism of inhibiting tumor cell proliferation and shows activity against a broad panel of human tumor cell lines in vitro: Abstract A 111.

24 Oct 2007

Trial of an individualized menopause decision aid

Being aware of the health risks associated with treating menopausal symptoms might only make it harder for women to decide what to do.

24 Oct 2007

75% of hospitalised patients suffer from malnutrition regardless of their pathology

23 Oct 2007

Gold-like drugs to treat arthritis

Scientists at Duke University Medical Center may have solved the mystery surrounding the healing properties of gold - a discovery they say may renew interest in gold salts as a treatment for rheumatoid arthritis and other inflammatory diseases.

22 Oct 2007

New polymer for use in joint reconstruction

Researchers in the Campbell Clinic Department of Orthopaedic Surgery at the University of Tennessee Health Science Center in Memphis, Tennessee, presented a paper that indicates a new polymer under study for applications in joint reconstruction can significantly reduce up to seven times the harmful chemicals formed as a result of the presence of wear particle debris in the body.

22 Oct 2007

Electronic medical records improve continuity of care for osteoporosis

Electronic medical records and outreach programs of e-mail messages, letters and phone calls to patients and their primary care providers after a bone fracture can dramatically improve the diagnosis and management of the patients' osteoporosis, according to a Kaiser Permanente study in the September issue of the Journal of the American Geriatrics Society.

22 Oct 2007

Funding source a major determinant in findings regarding adverse effects in corticosteroid studies

Studies of inhaled corticosteroids, medications frequently prescribed for asthma and other respiratory problems, appear less likely to find adverse effects if they are funded by pharmaceutical companies than if they are funded by other sources, according to a report in the October 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

22 Oct 2007

FDA approves approved Ixempra (ixabepilone) for advanced breast cancer

The U.S. Food and Drug Administration has approved Ixempra (ixabepilone), a new anti-cancer treatment, for use in patients with metastatic or locally advanced breast cancer who have not responded to certain other cancer drugs.

22 Oct 2007

Exercise improves thinking and reduces diabetes in overweight kids

Just three months of daily, vigorous physical activity in overweight children improves their thinking and reduces their diabetes risk, researchers say.

22 Oct 2007

Human cytomegalovirus may help doctors treat glioblastoma multiforme

A common human virus may prove useful in attacking the deadliest form of brain tumors, according to a study by researchers at Duke's Preston Robert Tisch Brain Tumor Center.

22 Oct 2007

Longer-living, healthier mouse holds clues to human ageing

A study by scientists at UCL (University College London) shows that mice lacking the insulin receptor substrate (IRS)-1 are more resistant to ageing than normal mice.

22 Oct 2007

Smoking, alcohol, being underweight and poor diet all risk factors for osteoporosis

If you smoke, drink more than two units of alcohol a day, are underweight, don't exercise or eat well, you could be setting yourself up for osteoporosis later in life, according to a new report issued by the International Osteoporosis Foundation (IOF).

22 Oct 2007

Canada leads in new heart valve replacement surgery

Canada is the world leader in a new surgical technique that is transforming the lives of patients too sick to undergo conventional treatment to replace diseased aortic valves.

22 Oct 2007

800-year-old mummies from Mongolia help advance DNA extraction

Dr. Heather Coyle and three forensic science graduate students at the University of New Haven have developed a new method for preparing certain skeletal remains for DNA extraction thanks to some 800-year-old mummies from Mongolia and the research the group is doing for the Smithsonian Institution.

22 Oct 2007

Smurfs a major cause of osteoarthritis

A new clinical trial seeks to predict who is most likely to experience osteoarthritis, and to test whether an experimental treatment can prevent it altogether.

19 Oct 2007

Antibiotics for upper respiratory tract infection, sore throat, or ear infection

Antibiotics are not justified to reduce the risk of complications after upper respiratory tract infection, sore throat, or ear infection, finds a study published on bmj.com.

19 Oct 2007

Abbott creates one molecule with two antibody functions

Abbott has reported that its scientists are the first to discover a proprietary technology that combines the function and specificity of two or more monoclonal antibodies (mAbs) into one molecular entity that demonstrates drug-like properties and manufacturing feasibility.

19 Oct 2007