Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Hospital follow-up services not necessary for all child cancer survivors

Many child cancer patients will benefit from ongoing follow-up, but others should be allowed to move on and put the experience of cancer behind them, say experts in this week's issue of the BMJ.

4 Apr 2008

Proteolix's Carfilzomib granted orphan drug designation

Proteolix, Inc. has announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation to carfilzomib, a selective blocker of proteasome activity for the treatment of multiple myeloma.

3 Apr 2008

De-marrowing helps bones mend faster

Could you strengthen bones and speed up recovery after fractures and breaks simply by removing some bone marrow with a syringe?

3 Apr 2008

Cellular grafting procedure helps young patients with knee disorder get active

At 14 years old, Adam Vasser of Los Altos, Calif., was an active kid who loved baseball.

2 Apr 2008

Stem cells from hair follicles may help 'grow' new blood vessels

For a rich source of stem cells to be engineered into new blood vessels or skin tissue, clinicians may one day look no further than the hair on their patients' heads, according to new research published earlier this month by University at Buffalo engineers.

31 Mar 2008

How humans make up for an 'inborn' vitamin C deficiency

A new study appears to explain how humans, along with other higher primates, guinea pigs and fruit bats, get by with what some have called an “inborn metabolic error”: an inability to produce vitamin C from glucose.

24 Mar 2008

Are dual cord blood banks the answer to increasing stem cell demand?

In this week's BMJ, two senior doctors, Professors Nicholas Fisk and Rifat Atun, analyse the UK's growing cord blood banking industry and the potential impact of a new bank that provides blood for both personal and public use.

24 Mar 2008

The effect of melatonin on colitis

In rats with experimental colitis, the marked increase in bacterial translocation in postcolitis rats has been reversed by melatonin administration.

19 Mar 2008

Survival mechanism of T lymphocytes uncovered

When an individual is challenged by a virus, a bacterium or any other infectious agent, several classes of white blood cells are being activated in order to fight the invasion.

19 Mar 2008

New interventional radiology treatment shows promise for complications from bone marrow, stem cell tranplants

The standard treatment to treat graft-versus-host disease (GVHD) after bone marrow or cord blood transplant is intravenous (IV) steroids that alter the immune response; however, it is not always effective and failure results in very high mortality.

19 Mar 2008

Study shows Parkinson's disease drug dopamine might work in cancer patients

A study published in the March 13 online issue of The Journal of Clinical Investigation shows that dopamine, a drug currently used to treat Parkinson's disease and other illnesses, also might work in cancer patients.

14 Mar 2008

Discovery of new species of bacteria that can live in hairspray

Scientists in Japan have discovered a new species of bacteria that can live in hairspray, according to the results of a study published in the March issue of the International Journal of Systematic and Evolutionary Microbiology.

10 Mar 2008

Research in diabetes surgery suggests origins of disease

Growing evidence shows that surgery may effectively cure Type 2 diabetes -- an approach that not only may change the way the disease is treated, but that introduces a new way of thinking about diabetes.

5 Mar 2008

Watery pools in bone marrow key to psoriatic arthritic damage

Researchers have learned more about how a leading drug prevents certain types of arthritis from eating away at bone, according to a study published in the March edition of the Annals of the Rheumatic Diseases.

4 Mar 2008

Protein in embryonic stem cells control malignant tumor cells

A protein that governs development of human embryonic stem cells (hESCs) also inhibits the growth and spread of malignant melanoma, the deadliest skin cancer, Northwestern University researchers have discovered.

4 Mar 2008

Thalidomide shows promise for treatment of recurrent ovarian cancer

Thalidomide, a drug blamed in the 1950s for causing birth defects, is now showing promise as a safe and effective treatment for women with recurrent ovarian cancer, according to a study led by a University of Minnesota Cancer Center researcher.

28 Feb 2008

Adult stem cells may be beneficial for certain cardiovascular disorders and autoimmune diseases

A review of previously published research suggests that stem cells harvested from an adult's blood or marrow may provide treatment benefit to select patients for some autoimmune diseases and cardiovascular disorders, according to an article in the February 27 issue of JAMA: The Journal of the American Medical Association.

27 Feb 2008

New proof-of-principle findings that thymic involution can be reversed in humans

Scientists at the Gladstone Institute of Virology and Immunology (GIVI) and the University of California, San Francisco (UCSF) have found that therapy can be used to stimulate the production of vital immune cells, called "T- cells," in adults with HIV infection.

21 Feb 2008

Single microRNA plays role in innate immune response

Over the last few years scientists have discovered hundreds of microRNAs - tiny RNAs that regulate the expression of protein-coding genes.

20 Feb 2008

Human stem cells aid stroke recovery in rats

Neural cells derived from human embryonic stem cells helped repair stroke-related damage in the brains of rats and led to improvements in their physical abilities, according to a new study by researchers at the Stanford University School of Medicine.

20 Feb 2008