Bone Mineral Density News and Research

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Amgen announces European approval of Prolia

Amgen Inc. today announced that the European Commission (EC) has granted marketing authorization for Prolia® (denosumab) for the treatment of osteoporosis in postmenopausal women at increased risk of fractures, and for the treatment of bone loss associated with hormone ablation in men with prostate cancer at increased risk of fractures.

28 May 2010

$Proton pump inhibitor use associated with fracture risk in postmenopausal women$

Proton pump inhibitor use associated with fracture risk in postmenopausal women

Proton pump inhibitors, medications that suppress acid in the stomach, appear to be associated with fractures in postmenopausal women and bacterial infections in many patients, and higher doses do not appear any more beneficial for treating bleeding ulcers, according to a series of reports in the May 10 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

11 May 2010

Obesity epidemic may be flattening out - still much to be done

The prevalence of childhood obesity might be stabilising in developed countries, but there is still much to be done to combat this major threat to health, according to a Seminar published on Online First and in an upcoming issue of The Lancet.

6 May 2010

Proper nutrition during multi-day stage races may prevent harmful changes in bone turnover: Study

The recent start of the North American cycling season marks the beginning of a physically demanding time for elite and professional bicycle racers who participate in multi-day stage races. Previous research has found that competitive cyclists have significantly lower bone mineral density than other endurance athletes, making them more susceptible to fractures.

6 May 2010

Study shows training in rhythmic gymnastics improves bone health in adolescent girls

According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism, long-term elite rhythmic gymnastics exerts positive effects on volumetric bone density and bone geometry in adolescent girls.

5 May 2010

$Seniors who consume high dietary protein are less likely to suffer hip fractures$

Seniors who consume high dietary protein are less likely to suffer hip fractures

Seniors who consume a higher level of dietary protein are less likely to suffer hip fractures than seniors whose daily dietary protein intake is less, according to a new study by the Institute for Aging Research of Hebrew SeniorLife in Boston, an affiliate of Harvard Medical School.

5 May 2010

AdvaCAL named official partner of National Osteoporosis Foundation

AdvaCAL® calcium supplements is proud to announce that it has been named as an official partner of the National Osteoporosis Foundation (NOF), the nations' leading voluntary health organization dedicated to osteoporosis and bone health. This designation is reserved for companies that provide financial support to NOF, with products judged to be consistent with the NOF mission.

5 May 2010

JGH researchers identify 13 new genes associated with osteoporosis, bone weakness

A team of international researchers has identified 20 genes associated with osteoporosis and bone weakness, including 13 genes never previously associated with the disease. Osteoporosis is a highly heritable trait, but this marks the largest international effort to conclusively identify genes linked to the often-devastating bone disorder.

4 May 2010

Researchers present positive results of Phase II clinical trial of eliglustat tartrate

Gaucher disease, a rare enzyme deficiency disorder, is one of many conditions with few approved treatment options for patients. In a study published online today in Blood, the journal of the American Society of Hematology, researchers present positive results of a Phase II clinical trial of eliglustat tartrate, an oral therapy in development to treat Gaucher disease.

4 May 2010

Exercise helps retain greater bone density: Researchers

The stage for osteoporosis is set well before menopause-but exercise can help rewrite the script, according to Medical College of Georgia researchers.

26 Apr 2010

Controlling actions of FSH may help treat osteoporosis in menopausal women

Diminished bone density is common among menopausal women and raises their risk of osteoporosis, bone fractures and subsequent complications. Research has traditionally focused on therapies that seek to maintain the level of estrogen in the body. This hormone seems to sustain bone health, but it drops to an extremely low level during and after menopause.

26 Apr 2010

Lipocine announced receipt of $2M development milestone payment from Abbott

Lipocine Inc. announced today the receipt of a $2 million development milestone payment from Abbott under the terms of its Licensing Agreement to develop and commercialize an oral testosterone product for hypogonadism, also known as low testosterone.

21 Apr 2010

Novartis Pharma AG initiates second Phase I trial for oral PTH1-34: Emisphere Technologies

Emisphere Technologies, Inc. today announced that Novartis Pharma AG has initiated a second Phase I trial for an oral PTH1-34 which uses Emisphere's Eligen Technology, and is in development for the treatment of postmenopausal osteoporosis. Emisphere Technologies is a biopharmaceutical company that focuses on a unique and improved delivery of pharmaceutical compounds and nutritional supplements using its Eligen Technology.

16 Apr 2010

Gilead Sciences doses first patient in Quad Phase III clinical program

Gilead Sciences, Inc. today announced that it has dosed the first patient in the Phase III clinical program evaluating its investigational fixed-dose, single-tablet "Quad" regimen of elvitegravir, cobicistat (formerly GS 9350), emtricitabine and tenofovir disoproxil fumarate.

13 Apr 2010

Ipsen, GTx expand partnership for toremifene 80 mg

Ipsen today announced the expansion of their partnership for the development and commercialization of toremifene 80 mg for the reduction of fractures in men with advanced prostate cancer on androgen deprivation therapy (ADT) and toremifene 20 mg for the prevention of prostate cancer in high risk patients with High Grade Prostatic Intraepithelial Neoplasia lesions (HGPIN).

23 Mar 2010

ARS study underlines the importance of vitamin D and its ability to help body utilize calcium

Increasing calcium intake is a common--yet not always successful--strategy for reducing bone fractures. But a study supported in part by the Agricultural Research Service (ARS) underscores the importance of vitamin D and its ability to help the body utilize calcium. The study also may explain why increasing calcium alone isn't always successful in dealing with this problem.

12 Mar 2010

Post-marketing safety studies for LABAs: AstraZeneca confident of SYMBICORT in treatment of asthma

On March 10-11, 2010, the Joint Advisory Committees of the U.S. Food and Drug Administration (FDA) -- including the Pulmonary-Allergy Drugs and the Drug Safety and Risk Management Advisory Committees -- discussed the design of post-marketing safety studies for long-acting beta-agonist (LABA)-containing products in the U.S., including SYMBICORT® (budesonide/formoterol fumarate dihydrate).

12 Mar 2010

Domiciliary parenteral nutrition helps children with serious intestinal problems live more normally

Children with serious intestinal problems have to be fed intravenously. There moreover, exist systems that enable intravenous feeding to be carried out at home. Mr I-aki Irastorza, paediatrician at the Cruces hospital in Bilbao, spent some 15 years analysing how serious intestinal problems in children were treated at the Great Ormond Street Children's Hospital in London. With the gathered data he has presented a highly novel PhD thesis at the University of the Basque Country.

9 Mar 2010

Soccer can be effective training method to reduce bone weakening that comes with increasing age

The observed improvements in bone mineral density, strength and postural balance due to recreational soccer are of particularly interest for a large group of women but also for elderly men, says project leader Associate Professor Peter Krustrup, University of Copenhagen, and continues "It is well known that the risk of falls and fractures increases with age as a result of weaker bones, poorer balance and attenuated ability to trigger rapid muscle force, but the present results suggest that soccer - and possibly other ball games - is an effective training method to reduce bone weakening that comes with increasing age".

4 Mar 2010

Merck’s MF/F Phase III study data presented at AAAAI annual meeting

Data from two Phase III studies of Merck’s investigational fixed-dose combinations of mometasone furoate and formoterol fumarate (MF/F) were presented by researchers today in two poster presentations at the American Academy of Allergy, Asthma & Immunology (AAAAI) annual meeting.

3 Mar 2010

Bone Mineral Density News and Research

Amgen announces European approval of Prolia

Proton pump inhibitor use associated with fracture risk in postmenopausal women

Obesity epidemic may be flattening out - still much to be done

Proper nutrition during multi-day stage races may prevent harmful changes in bone turnover: Study

Study shows training in rhythmic gymnastics improves bone health in adolescent girls

Seniors who consume high dietary protein are less likely to suffer hip fractures

AdvaCAL named official partner of National Osteoporosis Foundation

JGH researchers identify 13 new genes associated with osteoporosis, bone weakness

Researchers present positive results of Phase II clinical trial of eliglustat tartrate

Exercise helps retain greater bone density: Researchers

Controlling actions of FSH may help treat osteoporosis in menopausal women

Lipocine announced receipt of $2M development milestone payment from Abbott

Novartis Pharma AG initiates second Phase I trial for oral PTH1-34: Emisphere Technologies

Gilead Sciences doses first patient in Quad Phase III clinical program

Ipsen, GTx expand partnership for toremifene 80 mg

ARS study underlines the importance of vitamin D and its ability to help body utilize calcium

Post-marketing safety studies for LABAs: AstraZeneca confident of SYMBICORT in treatment of asthma

Domiciliary parenteral nutrition helps children with serious intestinal problems live more normally

Soccer can be effective training method to reduce bone weakening that comes with increasing age

Merck’s MF/F Phase III study data presented at AAAAI annual meeting

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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