CLARITY News and Research

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The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.

American College of Radiology issues risk mitigation strategies to address contrast media shortage

GE Healthcare was forced to shut a production plant in April because of a COVID-19 outbreak in Shanghai, China.

23 Jun 2022

Study shines new light on the role of key Parkinson’s disease protein

One of the hallmarks of Parkinson's disease (PD) is the accumulation in the brain of a protein known as alpha-synuclein. For more than two decades, alpha-synuclein has been a focal point of attention for researchers, clinicians and drug makers interested in PD.

9 Jun 2022

Lawmaker takes on insurance companies and gets personal about his health

Scott Wiener made a startling revelation at a spring legislative committee hearing: "I was in the hospital. I experienced the most intense abdominal pain that I could even imagine."

9 Jun 2022

SARS-CoV-2 ORF8 protein binds to dendritic cells and induces a hyper-inflammatory cytokine storm

In a recent study posted to the bioRxiv* pre-print server, researchers examined how the interaction of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame 8 (ORF8) protein with host dendritic cells (DCs) induced cytokine storm.

8 Jun 2022

Review sets out new plans to create the biggest shake-up in health and social care leadership

The Health and Social Care Secretary Sajid Javid has welcomed the publication of an independent review of health and adult social care leadership, led by General Sir Gordon Messenger and Dame Linda Pollard - and, in what will be the biggest shake-up in health and social care leadership in a generation, is accepting all seven transformative recommendations they have put forward.

7 Jun 2022

Immune modulator drugs improved clinical status, reduced deaths among patients hospitalized with COVID-19

A large randomized, placebo-controlled clinical trial led by the National Institutes of Health shows that treating adults hospitalized with COVID-19 with infliximab or abatacept - drugs widely used to treat certain autoimmune diseases - did not significantly shorten time to recovery but did substantially improve clinical status and reduce deaths.

2 Jun 2022

New digital tool provides effective support for the treatment of pediatric obesity

A mobile app that shows a child's weight development in real-time for children with obesity provides greater weight loss compared to conventional care.

31 May 2022

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

In a recent study posted to the Research Square* preprint server, researchers assessed whether disturbances in the gut microbiota weaken the serological response to the coronavirus disease 2019 (COVID-19) vaccine in inflammatory bowel disease (IBD) patients.

25 May 2022

Researchers examine how aging impacts listening effort in cochlear-implant users

Degraded acoustic signals can make hearing difficult for anyone, but differences in cognitive abilities, age-related changes, and the use of cochlear implants may exacerbate the problem.

24 May 2022

New covered California leader urges renewal of enhanced federal aid for health premiums

When she was Pennsylvania's insurance commissioner, Jessica Altman, the appointee of a Democratic governor, often bumped against the political limits of health care policy in a state where Republicans controlled the legislature.

18 May 2022

How has COVID-19 affected maternal mental health?

Writing in the journal Reproductive Health, two researchers examine the unexpected impact of the virus on maternal mental health.

15 May 2022

Normal-appearing skin of lupus patients predisposed to flares and rashes, study finds

People with lupus have overactive immune systems that attack their own tissue, causing inflammation throughout the body.

3 May 2022

FFC invites customers to rate and review its services

The Flood Forecasting Centre (FFC) produces daily forecasts that help emergency responders prepare for flooding.

3 May 2022

How a former Catholic priest is navigating a California Medicaid plan through big changes

For Michael Hunn, the path from priesthood to health care was seamless.

14 Apr 2022

Chromatin accessibility as an early marker of severe COVID-19

A new study explores the possible use of chromatin remodeling in predicting a severe clinical trajectory for COVID-19.

11 Apr 2022

It’s your choice: You can change your views of aging and improve your life

People's beliefs about aging have a profound impact on their health, influencing everything from their memory and sensory perceptions to how well they walk, how fully they recover from disabling illness, and how long they live.

11 Apr 2022

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

In a recent study posted to the bioRxiv* preprint server, researchers developed aminoadamantane nitrates compounds that inhibit the ion channels formed by the envelope (E) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and enable targeted drug delivery of nitric oxide (NO)-related group for S-nitrosylation of host angiotensin-converting enzyme 2 (ACE2), which would inhibit ACE2 binding with the viral spike (S) protein and thereby inhibit viral replication in the host.

11 Apr 2022

CLARITY News and Research

Further Reading

American College of Radiology issues risk mitigation strategies to address contrast media shortage

Study shines new light on the role of key Parkinson’s disease protein

Lawmaker takes on insurance companies and gets personal about his health

SARS-CoV-2 ORF8 protein binds to dendritic cells and induces a hyper-inflammatory cytokine storm

Review sets out new plans to create the biggest shake-up in health and social care leadership

Immune modulator drugs improved clinical status, reduced deaths among patients hospitalized with COVID-19

New digital tool provides effective support for the treatment of pediatric obesity

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

Researchers examine how aging impacts listening effort in cochlear-implant users

New covered California leader urges renewal of enhanced federal aid for health premiums

How has COVID-19 affected maternal mental health?

Normal-appearing skin of lupus patients predisposed to flares and rashes, study finds

FFC invites customers to rate and review its services

How a former Catholic priest is navigating a California Medicaid plan through big changes

Chromatin accessibility as an early marker of severe COVID-19

It’s your choice: You can change your views of aging and improve your life

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

Stimulation of the auditory cortex improves speech perception over background noise

Flinders research uncovers how enteric nervous system in the gut communicates with the brain

Newly emerged-hygiene issue in the current lifestyles of wearing face masks during the COVID-19 pandemic

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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