CLARITY News and Research

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The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.

Gene therapy does not slow or halt progression of cell loss in Leber congenital amaurosis

Independent clinical trials, including one conducted at the Scheie Eye Institute at the Perelman School of Medicine, have reported safety and efficacy for Leber congenital amaurosis (LCA), a congenital form of blindness caused by mutations in a gene (RPE65) required for recycling vitamin A in the retina. Inherited retinal degenerative diseases were previously considered untreatable and incurable.

23 Jan 2013

Gene therapy improves vision but does not halt progression of cell loss

22 Jan 2013

QrxPharma to resubmit MOXDUO NDA with FDA

QRxPharma Limited announced today that the steps necessary for approval of immediate release MOXDUO have been clarified with the United States Food and Drug Administration (FDA).

17 Jan 2013

Scientists develop two novel model systems for human corneal endothelium

Human corneal endothelial cells (HCEnCs) form a monolayer of hexagonal cells whose main function is to maintain corneal clarity by regulating corneal hydration. Cell loss due to aging or corneal endothelial disorders, such as Fuchs dystrophy, can lead to cornea edema and blindness, resulting in the need for cornea transplants.

28 Dec 2012

FDA seeks input from states on drug compounders

FDA Commissioner Margaret Hamburg convened a meeting that included federal officials and representatives from state boards of pharmacy and governors' offices. Meanwhile, the Los Angeles Times reports on "rogue pharmacists."

21 Dec 2012

Elekta receives clearance for Clarity 4D Monitoring software

Elekta has received 510(k) clearance for its Clarity 4D Monitoring software, enabling U.S. medical centers to implement this new way of reducing the uncertainty caused by prostate motion during radiation treatment.

From Elekta 17 Dec 2012

House Republicans assail administration on health law implementation

Members of the Energy and Commerce subcommittee on health assert administration officials have not been helpful to states.

14 Dec 2012

Yoga can provide students with many emotional and physical benefits

While many university professors are busy with study groups and student meetings in preparation for final exams, Sandi Tenfelde, PhD, RN, ANP, CYI, has turned to sun salutations and savasanas.

13 Dec 2012

Environmental tobacco smoke exposure during pregnancy may harm child’s health

It is a known fact that active maternal smoking during pregnancy has negative effects on child health, such as attention deficit and hyperactivity disorder (ADHD). However, new research suggests that second hand smoke, or environmental tobacco smoke (ETS), may be just as harmful.

5 Dec 2012

'Fiscal Cliff' talks morphing into high-stakes game of political chicken

White House negotiators and GOP lawmakers remain at odds over a deficit-reduction plan with only weeks to go before automatic spending cuts and tax increases are triggered.

3 Dec 2012

HHS releases new insurance exchange rules, includes controversial surcharges

Health insurance companies will have to pay to play in new health insurance markets coming under President Barack Obama's health care law, the administration said in a regulatory notice issued Friday. The Health and Human Services department is proposing a "user fee" amounting to 3.5 percent of premiums for health insurers who want to offer policies in new federal exchanges coming in 2014.

2 Dec 2012

Fiscal cliff: Dems, GOP sparring publicly over entitlement cuts, including Medicare

President Barack Obama is ready to entertain Republican proposals for spending cuts, but GOP lawmakers must first commit to higher tax rates on the rich and specify what additional spending cuts they want in a deal to avoid the looming "fiscal cliff," Treasury Secretary Timothy Geithner said. "The ball really is with them now," Geithner, one of the president's chief negotiators with Capitol Hill, said during appearances on five Sunday talk shows.

2 Dec 2012

UCB directs national effort to educate public about Crohn's disease

In recognition of Crohn's and Colitis Awareness Week (December 1-7), UCB, Inc. is directing a national effort to educate the public about Crohn's disease and inspire those living with the condition to speak out about it.

1 Dec 2012

Journal article proposes framework to guide career development in health systems improvement

The sheer number of efforts aimed at improving the quality and efficiency of the U.S. health care system - ranging from portions of the national Affordable Care Act to local programs at individual hospitals and practices - reflects the urgency and importance of the task.

30 Nov 2012

Microscope system designed to acquire very low-light bioluminescence images introduced in North America by Olympus America

A benchtop commercial microscope system designed to acquire very low-light bioluminescence images has now been introduced in North America by Olympus America. The LV200 stand-alone microscope system is already being used to capture images of living cells and tissues by researchers in Europe and Japan.

From Evident Corporation - Life Sciences 29 Nov 2012

GE Healthcare introduces new LOGIQ E9 with XDclear

Today at RSNA 2012, GE Healthcare is introducing the new LOGIQ E9 with XDclear, a new general imaging ultrasound system.

26 Nov 2012

New research provides unprecedented clarity to aging process

For the first time, scientists at Fred Hutchinson Cancer Research Center have defined key events that take place early in the process of cellular aging.

23 Nov 2012

Senators pledge regulation of compounding pharmacies

At a Capitol Hill hearing, senators from both parties promised to take action following a meningitis outbreak that killed 32 people.

17 Nov 2012

General guidelines to understand allergic skin conditions

Winter months can bring on the itch as cold weather and indoor heat dry out the skin. It's possible, suggests Chicago allergist, Brian Rotskoff, MD of Clarity Allergy Center, that your winter itch could be caused by more than just the weather. For some people itchy, dry skin is just that, but for others it can be a symptom of atopic dermatitis (eczema), contact dermatitis, or hives (urticaria).

16 Nov 2012