CLARITY News and Research

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The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.

Report makes recommendations clarifying the ethics and oversight of chimeric research

A new report on the ethics of crossing species boundaries by inserting human cells into nonhuman animals – research surrounded by debate – makes recommendations clarifying the ethical issues and calling for improved oversight of this work.

13 Dec 2022

Quanterix’s Simoa® technology drives advances in Alzheimer’s disease research presented at 2022 Clinical Trials On Alzheimer’s Disease (CTAD) conference

Quanterix Corporation, a company fueling scientific discovery through ultrasensitive biomarker detection, today announced that its Simoa® technology has powered important advances in ongoing clinical trials for the treatment of Alzheimer’s disease (AD). The findings were presented at the 15th Clinical Trials on Alzheimer’s Disease (CTAD) conference held in San Francisco, CA from November 29 to December 2, 2022.

From Quanterix 12 Dec 2022

Researchers identify micronutrient supplementation to reduce cardiovascular risk

Healthy diets are rich in antioxidants like amino acids, omega-3 fatty acids and vitamin C, but exactly how beneficial these micronutrients are for cardiovascular health has long been controversial.

6 Dec 2022

Study reveals the widespread impact of pandemic on long COVID patients and people with other illnesses

Long COVID patients can experience many of the same lingering negative effects on their physical, mental, and social well-being as those experienced by people who become ill with other, non-COVID illnesses, new research suggests.

1 Dec 2022

UQ student awarded national prize for debunking common autism myth

A University of Queensland PhD student has been awarded a national prize for debunking a common myth about children with autism.

30 Nov 2022

Study finds no benefits from angiotensin receptor blocker treatment for COVID-19

In a recent study published in the BMJ, researchers conducted a phase three, multicenter, randomized controlled trial to evaluate the effect of using angiotensin receptor blockers that disrupt the renin-angiotensin system on the clinical outcomes of individuals with coronavirus disease 2019 (COVID-19).

21 Nov 2022

Minority women's perinatal experiences overshadowed by isolation and fear due to changing COVID-19 policies

Black, Indigenous and other women of color who were pregnant or gave birth during the pandemic said these experiences were overshadowed by isolation, confusion and fear, much of it caused by unclear or frequently changing institutional policies, according to a new study.

16 Nov 2022

Developing a cell atlas for the human brain

Researchers are developing a cell atlas -; a comprehensive reference of all cell types, including their location, shape, and distribution -; for the human brain.

9 Nov 2022

New study provides more clarity about giving steroids during pediatric open-heart surgery

For more than four decades, doctors have been split on whether giving steroids during a pediatric open-heart surgery could be helpful for post-operative recovery.

6 Nov 2022

Two heart failure therapies prove to be nearly identical in reducing death

In a head-to-head comparison of two so-called 'water pills' that keep fluid from building up in patients with heart failure, the therapies proved nearly identical in reducing deaths, according to a large study led by Duke Health researchers.

6 Nov 2022

Study finds low absolute risk of glomerular disease relapse associated with COVID-19 vaccination

Several reports have described a relapse of certain autoimmune kidney diseases in patients after they've received COVID-19 vaccines, but it's unclear if this association is real or a coincidence.

4 Nov 2022

Understanding how patients and families describe major medical treatments

When patients and their families face important decisions about major medical treatments, understanding how they describe them in their own words may help clinicians provide clarity and support through the decision-making process.

1 Nov 2022

Hospitals said they lost money on Medicare patients. Some made millions, a state report finds.

Atrium Health, the largest hospital system in North Carolina, has declared publicly that in 2019 it provided $640 million in services to Medicare patients that were never paid for, by far the largest "community benefit" it provided that year.

25 Oct 2022

Scientists map structure of the hepatitis C virus E1E2 glycoprotein complex

A team led by scientists at Scripps Research and the University of Amsterdam has achieved an important goal in virology: mapping, at high resolution, critical proteins that stud the surface of the Hepatitis C virus (HCV) and enable it to enter host cells.

20 Oct 2022

Beckman Coulter Life Sciences presenting at ASHG

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, will have a full team of dedicated professionals and informative programming at the American Society of Human Genetics (ASHG) Annual Meeting October 25-29, 2022 in Los Angeles, California at the Los Angeles Convention Center.

From Beckman Coulter Life Sciences 20 Oct 2022

Scientists investigate the antibody titers post-mRNA COVID-19 booster vaccine in the elderly

The coronavirus 2019 disease (COVID-19) pandemic has affected millions worldwide and claimed multiple lives.

6 Oct 2022

Eligibility criteria lack clarity, justification for excluding people with disabilities from clinical trials

Despite constituting the largest minority group in the U.S. and expressing interest in participating in clinical trials, people with disabilities remain excluded.

3 Oct 2022

Does high vaccine coverage among the adult population grant the unvaccinated younger population indirect protection against SARS-CoV-2?

Researchers investigated whether the mass vaccination of the adult population of Schwaz, Austria, against SARS-CoV-2 conferred an indirect protective effect on the proportion of unvaccinated children in the population.

3 Oct 2022

At this recovery center, police cope with the mental health costs of the job

Ken Beyer can't think of a day in the past few months when his phone didn't flutter with calls, text messages, and emails from a police department, a sheriff's office, or a fire station seeking help for an employee.

27 Sep 2022

Is there any impact of COVID-19 vaccines on the fertility of men and women of reproductive age?

Researchers assessed the impact of SARS-CoV-2 vaccines on human fertility.

19 Sep 2022