Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

New insights into renal cell cancer

A new mouse model is providing valuable insight into the biochemical pathways that are associated with development of renal cysts and renal cell cancer.

10 Apr 2007

UT Metroplex institutions to collaborate on biomedical research

Researchers from the three University of Texas campuses in the Dallas-Fort Worth metropolitan area are combining their expertise in biomedical science, engineering and physical sciences on projects aimed at solving real-world medical problems.

5 Apr 2007

Cost-effectiveness analysis of variceal ligation vs. beta-blockers for primary prevention of variceal bleeding

Endoscopic variceal ligation is cost-effective relative to beta-blockers for the prevention of variceal bleeding in cirrhotic patients if quality of life-years are considered.

4 Apr 2007

NAFLD fibrosis score helps predict advanced fibrosis in patients with nonalcoholic fatty liver disease

Certain routine demographic, clinical, and laboratory values can be used to identify advanced fibrosis in patients with nonalcoholic fatty liver disease (NAFLD).

4 Apr 2007

Hand-assisted radical nephrectomy study

Since the 1960's, radical nephrectomy through an open surgical approach has been the accepted standard of care for patients with localized and locally advanced renal cell carcinoma (RCC).

3 Apr 2007

Lack of Olig1 protein in lung tumors may increase risk of death

A study of human lung tumors indicates that lung cancer patients who lack a particular protein may do more poorly than those with normal levels of that same protein.

2 Apr 2007

Gender differences and skin cancer

Inherent gender differences – instead of more sun exposure – may be one reason why men are three times more likely than women to develop certain kinds of skin cancer, say researchers at Ohio State University Medical Center.

2 Apr 2007

Effect of gender on the development of UVB-induced skin cancers

Inherent gender differences "instead of more sun exposure" may be one reason why men are three times more likely than women to develop certain kinds of skin cancer, say researchers at Ohio State University Medical Center.

2 Apr 2007

American Cancer Society issues recommendation on MRI for breast cancer screening

An expert panel convened by the American Cancer Society has developed new recommendations for the use of magnetic resonance imaging (MRI) for women at increased risk for breast cancer, and recommends annual screening using MRI in addition to mammography for women with a 20-25 percent or greater lifetime risk of the disease.

29 Mar 2007

Switching to an aromatase inhibitor provides mortality benefit in early breast carcinoma

For breast cancer patients taking tamoxifen, switching to an aromatase inhibitor within three years significantly improves survival rates, according to a new study.

12 Feb 2007

Women under 25 should be offered cervical screening

Last month, the British Medical Journal reported a fall in the number of young women attending smear tests. Now, two senior doctors warn that a new policy not to screen women aged 20-24 may be a factor in falling coverage and could increase the risk of cancer developing in young women.

11 Feb 2007

Hepatitis C virus replication in transfected and serum-infected cultured human fetal hepatocytes

Researchers open the way for improved study of hepatitis C virus by devising a novel virus culture system that allows replication of patient-isolated virus in nontransformed hepatocytes, instead of culture-adapted virus strains in transformed cell lines.

23 Jan 2007

Nanoparticles from crab shells show promise for drug delivery

Nanoparticles made of chitosan, a naturally occuring polymer isolated from crab and shrimp shells, have shown promise as carriers of anticancer drugs, antitumor genes, and other novel therapeutic agents.

22 Jan 2007

Cetuximab may prolong survival for head and neck cancer patients

Preliminary findings show adding the chemotherapy drug cetuximab (brand name Erbitux) to radiation therapy and chemotherapy may help some patients with head and neck cancer live longer, according to a study presented at the plenary session of the Multidisciplinary Head and Neck Cancer Symposium, co-sponsored by the American Society for Therapeutic Radiology and Oncology, the American Society for Clinical Oncology and the American Head and Neck Society.

18 Jan 2007

Nanoparticles yield delivery tools for therapeutic nucleic acids

Cancer researchers hold great hope that nucleic acid-based therapeutics, such as anticancer genes, antisense oligonucleotides, and small interfering RNA (siRNA) molecules, will prove to be powerful antitumor agents.

16 Jan 2007

DNA methylation and breast cancer

A new study using mastectomy tissue shows that precancerous changes can occur in normal-appearing areas of the breast as distant as two inches from a tumor's edge.

10 Jan 2007

Several specific genetic alterations associated with development of smoking-related cancers

Preliminary research indicates that several specific genetic alterations are associated with the development of smoking-related head and neck skin cancers, according to a report in the January 10 issue of JAMA: The Journal of the American Medical Association.

9 Jan 2007

Lifestyle decisions that may stave off onset of cancer

Personal choices, such as smoking and consumption of fatty foods, have long been linked to increased cancer risk. During recent years, scientists have been seeking to isolate a variety of lifestyle decisions that may stave off the onset of cancer or even reduce tumor formation in their early stages.

14 Nov 2006

A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas

In a dramatic demonstration of the power of nanotechnology, a team of investigators has designed a nanoscale, polymeric drug delivery vehicle that when loaded with a widely used anticancer agent cures colon cancer in mice with a single dose.

13 Nov 2006

Eating lots of bread associated with increased risk of renal cell carcinoma

A case-control study of more than 2300 Italians has found a significant association between high bread consumption and renal cell carcinoma. Eating a lot of pasta and rice may also raise the risk, while eating many vegetables may lower the risk.

20 Oct 2006