Carcinoma News and Research

RSS

Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

Numbing agent lidocaine may have cancer-fighting properties

Lidocaine-;often used as numbing agent for outpatient medical procedures-;activates certain bitter taste receptors through two unique mechanisms that result in cancer cell death, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

22 Nov 2023

Urban environmental quality linked to breast cancer incidence

A Duke Health analysis of breast cancer in North Carolina showed that the state's urban counties had higher overall incidences of disease than rural counties, especially at early stages upon diagnosis.

20 Nov 2023

Study finds increased liver cancer risk among Mexican Americans in subsequent generations

In the United States, liver cancer rates have more than tripled since 1980. Some groups, including Latinos, face an even higher risk than the general population-;but researchers do not fully understand why.

20 Nov 2023

Researchers develop gene classifier to predict DCIS risk of cancer progression

A team of researchers mapping a molecular atlas for ductal carcinoma in situ (DCIS) has made a major advance toward distinguishing whether the early pre-cancers in the breast will develop into invasive cancers or remain stable.

20 Nov 2023

Assessing DDX53 as a potential early esophageal cancer antigen

A new research paper was published in Oncoscience (Volume 10) on November 10, 2023, entitled, "An immunoinformatics assessment of the cancer testis antigen, DDX53, as a potential early esophageal cancer antigen."

17 Nov 2023

CMA clarifies cooperation on combination therapies to speed up patient access to vital treatments

The Competition and Markets Authority (CMA) has today issued a statement clarifying that certain types of engagements between competing drug firms working on 'combination therapies' will not be prioritized for investigation - making it easier for drug firms to work together to develop vital treatments for use in the NHS.

17 Nov 2023

Coffee and COVID: Study finds coffee inhibits SARS-CoV-2, offers new dietary defense strategy

Study discovers that coffee, especially its bioactive compounds like chlorogenic acids, can inhibit SARS-CoV-2 entry and reduce ACE2 and TMPRSS2 levels, indicating that coffee intake might be a potential dietary strategy for COVID-19 prevention.

16 Nov 2023

Landmark studies present new era for bladder cancer treatment

After 40 years of treating metastatic bladder cancer with chemotherapy as a primary treatment, scientists now present a new approach using immunotherapy combinations.

16 Nov 2023

AI model predicts patient outcomes across multiple cancer types

Investigators from the UCLA Health Jonsson Comprehensive Cancer Center have developed an artificial intelligence (AI) model based on epigenetic factors that is able to predict patient outcomes successfully across multiple cancer types.

16 Nov 2023

Study links lifestyle choices and gender to severity of fatty liver disease in workers

Study investigates the correlation between lifestyle factors, gender, inflammation, liver dysfunction, and metabolic abnormalities with fatty liver disease severity, revealing that men are at higher risk and lifestyle choices significantly impact the disease's progression.

15 Nov 2023

Stand Up To Cancer unveils new gastroesophageal cancer research teams and awards

Stand Up To Cancer (SU2C) today announced three Research Teams focused on bringing new therapies to clinical trials for the treatment of gastroesophageal cancer (GEC).

15 Nov 2023

Study reveals mechanisms restricting oncogene-driven skin cancer formation

To form a cancer, cells need to accumulate oncogenic mutations that confer tumor-initiating properties.

15 Nov 2023

Unlocking the cure for hepatitis B virus: Challenges and opportunities

Hepatitis B virus (HBV) is a significant public health problem, with over 296 million people chronically infected worldwide.

13 Nov 2023

AI-based model can predict therapy outcome in ovarian cancer patients

A model based on artificial intelligence is able to predict the therapy outcome (measured by volumetric reduction of tumor lesions) in 80% of ovarian cancer patients.

13 Nov 2023

Pioneering study finds predictive biomarker in lung adenocarcinoma

The potential of the transcriptome of tumor-adjacent normal lung tissue in predicting the prognosis of lung cancer.

13 Nov 2023

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

A prospective path for allogeneic cellular immunotherapies.

13 Nov 2023

Cannabis use alters DNA methylation, with implications beyond smoking effects

A large-scale meta-analysis in Molecular Psychiatry reveals that lifetime cannabis use is associated with DNA methylation changes in peripheral blood, which could have implications for understanding the long-term health effects of cannabis consumption.

8 Nov 2023

New insights into the pathogenesis of chronic liver diseases

Fatty liver diseases (FLD) have become a significant health concern worldwide, affecting millions. The two most common types of FLD are non-alcoholic fatty liver disease (NAFLD) and alcoholic-associated liver disease (ALD). NAFLD is associated with obesity, insulin resistance, and metabolic syndrome, while ALD is caused by excessive alcohol consumption.

7 Nov 2023

Unraveling the role of HER2 mutant alleles in breast cancer

A new editorial paper was published in Oncotarget's Volume 14 on October 31, 2023, entitled, "The uncharted role of HER2 mutant alleles in breast cancer."

6 Nov 2023

Kicking the habit: Oral microbiota bounces back five years after quitting smoking

Study finds that smoking reshapes the oral microbiome by favoring anaerobic bacteria, potentially contributing to health risks, yet the effects may reverse if smoking is ceased for over five years, restoring a microbiota similar to that of non-smokers.

5 Nov 2023