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UT Southwestern scientists discover gene that protects gut from IBD

UT Southwestern Medical Center researchers have identified a gene that protects the gut from inflammatory bowel disease.

2 Feb 2017

Scientists develop unique method to fix genes in living organisms

A unique gene-editing method that efficiently inserts DNA into genes located in dividing and non-dividing cells of living rats has been developed by a team of international researchers, including scientists from KAUST.

31 Jan 2017

ACMG issues new Points to Consider statement on potential clinical application of genome editing

The American College of Medical Genetics and Genomics is weighing in on the genome editing/CRISPR debate with a new Points to Consider statement, "Genome Editing in Clinical Genetics."

29 Jan 2017

TSRI researchers develop first stable semisynthetic single-celled organism

Life’s genetic code has only ever contained four natural bases. These bases pair up to form two “base pairs”—the rungs of the DNA ladder—and they have simply been rearranged to create bacteria and butterflies, penguins and people. Four bases make up all life as we know it.

25 Jan 2017

CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets.

19 Jan 2017

Researchers use CRISPR-based genetic screening to identify three promising HIV treatment targets

Investigators from Whitehead Institute, the Ragon Institute of MGH, MIT and Harvard and the Broad Institute of MIT and Harvard have used CRISPR-Cas9 gene-editing technology to identify three promising new targets for treatment of HIV infection.

20 Dec 2016

New IDT webinar to highlight benefits of using RNP complexes for efficient genome modifications

Integrated DNA Technologies will host an informative webinar entitled ‘Ribonucleoprotein delivery of CRISPR-Cas9 reagents for increased gene editing efficiency’ on December 14, 2016.

9 Dec 2016

Researchers uncover first ‘off-switches’ for better control of CRISPR/Cas9 gene editing

CRISPR/Cas9 genome editing is quickly revolutionizing biomedical research, but the new technology is not yet exact. The technique can inadvertently make excessive or unwanted changes in the genome and create off-target mutations, limiting safety and efficacy in therapeutic applications.

9 Dec 2016

Synthetic sgRNA for CRISPR genome editing

Chemically synthesized single guide RNA is the best way to do CRISPR genome editing. It is more pure than biological methods of creating guide RNAs, like in vitro transcription or plasmids. As a result, sgRNA leads to more consistency and higher quality.

8 Dec 2016

Scientists discover how motors maneuver cells' intricate roadway system

Much like motors power our cars, they also ensure that proteins get to the right place in our cells, and a wide variety of diseases - from cancer to heart problems - can result when they don't.

7 Dec 2016

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

CRISPR/Cas9, a powerful genome editing tool, is showing promise for efficient correction of disease-causing mutations.

1 Dec 2016

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

The Allen Institute for Cell Science has released the Allen Cell Collection: the first publicly available collection of gene edited, fluorescently tagged human induced pluripotent stem cells that target key cellular structures with unprecedented clarity.

30 Nov 2016

Researchers use new gene-editing system to hasten quest to cure HIV+ patients

Researchers at UC San Francisco and the academically affiliated Gladstone Institutes have used a newly developed gene-editing system to find gene mutations that make human immune cells resistant to HIV infection.

26 Oct 2016

Texas Biomed researcher seeks to identify molecular mechanisms underlying early atherosclerosis

Texas Biomedical Research Institute Staff Scientist Dr. Genesio Karere was recently awarded a $609,568 grant from the National Institutes of Health to study and identify molecular mechanisms underlying early atherosclerosis.

25 Oct 2016

Penn researchers identify new immune system mechanism to fight against infections

The innate immune system serves as a first-line defense, responding to infections almost immediately after a pathogen makes its way into the body.

17 Oct 2016

Researchers develop mouse model to investigate behavioral effects of eating disorder gene

Giving mice a gene mutation linked to eating disorders in people causes feeding and behavior abnormalities similar to symptoms often seen in patients with eating disorders. Only female mice are affected by the gene mutation, and some of the abnormalities in the female mice depend on whether they are housed alone or together with other mice.

13 Oct 2016

Cas9 News and Research

UT Southwestern scientists discover gene that protects gut from IBD

Scientists develop unique method to fix genes in living organisms

ACMG issues new Points to Consider statement on potential clinical application of genome editing

TSRI researchers develop first stable semisynthetic single-celled organism

CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

Researchers use CRISPR-based genetic screening to identify three promising HIV treatment targets

New IDT webinar to highlight benefits of using RNP complexes for efficient genome modifications

Researchers uncover first ‘off-switches’ for better control of CRISPR/Cas9 gene editing

Synthetic sgRNA for CRISPR genome editing

Scientists discover how motors maneuver cells' intricate roadway system

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

Researchers use new gene-editing system to hasten quest to cure HIV+ patients

Texas Biomed researcher seeks to identify molecular mechanisms underlying early atherosclerosis

Penn researchers identify new immune system mechanism to fight against infections

Researchers develop mouse model to investigate behavioral effects of eating disorder gene

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

Scientists aim to explore parasite's genomic architecture for varying expression of antigens

Imran Noorani receives Brainlab Community Neurosurgery Abstract Award at 2016 CNS annual meeting

Synthego introduces CRISPRevolution synthetic sgRNA kit for fast, high-throughput gene editing

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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