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Healthy adults with shorter telomere length more likely to develop upper respiratory infection

Among healthy adults who were administered a cold virus, those with shorter telomere length (a structure at the end of a chromosome) in certain cells were more likely to develop experimentally-induced upper respiratory infection than participants with longer telomeres, according to results of preliminary research published in the February 20 issue of JAMA.

20 Feb 2013

Scientists demonstrate advantages of wavelength-modulated Raman spectroscopy

Raman spectroscopy has enabled incredible advances in numerous scientific fields and is a powerful tool for tissue classification and disease recognition, although there have been considerable challenges to using the method in a clinical setting. Scientists have now demonstrated the advantages of wavelength-modulated Raman spectroscopy, opening the door to wider biomedical and clinical applications such as real-time assessment of tissues during surgery.

20 Feb 2013

CINJ researcher receives PCF grant for study on lung cancer detection and prevention

Sharon Pine, PhD, a researcher at The Cancer Institute of New Jersey and assistant professor of medicine at the University of Medicine of Dentistry of New Jersey-Robert Wood Johnson Medical School has been awarded a two-year, $80,000 dollar research grant from the Prevent Cancer Foundation.

20 Feb 2013

J Cell Mol Med, Microbial Biotechnology join Wiley Open Access publishing program

John Wiley & Sons, Inc., announced today that Journal of Cellular and Molecular Medicine and Microbial Biotechnology have joined the Wiley Open Access publishing program. All articles in these two journals are now open access and free to view, download and share.

20 Feb 2013

Ipsen, Inspiration Biopharmaceuticals sell IB1001 hemophilia B product to Cangene

Inspiration Biopharmaceuticals and Ipsen today announced the closing of the sale of the proprietary hemophilia B product, IB1001 (recombinant FIX), to Cangene Corporation.

20 Feb 2013

Immature malaria parasites more resistant to treatment with artemisinin

New research has revealed that immature malaria parasites are more resistant to treatment with key antimalarial drugs than older parasites, a finding that could lead to more effective treatments for a disease that kills one person every minute and is developing resistance to drugs at an alarming rate.

20 Feb 2013

Study may help design better DAA drug cocktails to treat HCV

Hepatitis C virus (HCV) infection affects about 4 million in the United States and is the primary cause of liver cirrhosis and liver cancer. Current therapy against HCV is suboptimal. Daclatasvir, a direct acting antiviral (DAA) agent in development for the treatment of HCV, targets one of the HCV proteins (i.e., NS5A) and causes the fastest viral decline (within 12 hours of treatment) ever seen with anti-HCV drugs.

20 Feb 2013

TIR-199 shows promise in fighting renal cancer

Chemists at the University of California, Riverside have developed a compound that holds much promise in the laboratory in fighting renal (kidney) cancer.

20 Feb 2013

Study finds chemical cues that allow seals’ brain to remain half awake and asleep

A new study led by an international team of biologists has identified some of the brain chemicals that allow seals to sleep with half of their brain at a time.

20 Feb 2013

Targeting p38alpha MAPK isoform can help treat CNS inflammatory diseases

A study by a leading Alzheimer's researcher at the University of Kentucky provides new evidence that will help researchers home in on the molecular mechanisms involved in inflammation of the central nervous system (CNS) and aid drug-development strategies for treating inflammatory neurological diseases.

20 Feb 2013

Mobile phones could help diagnose, properly treat malaria in remote areas, study says

"Mobile phones, along with local knowledge and field support, can help to ensure the effective diagnosis and treatment of malaria in remote rural areas, according to a study" conducted in Bangladesh and published this month in Malaria Journal, SciDev.Net reports.

20 Feb 2013

Tiny microscope can help scientists observe neuronal firings in the brain

If you want to read a mouse's mind, it takes some fluorescent protein and a tiny microscope implanted in the rodent's head.

20 Feb 2013

Elsevier receives three American Journal of Nursing 2012 Book of the Year awards

Elsevier, a world-leading provider of scientific, technical and medical information products and services, was recognized with three American Journal of Nursing (AJN) 2012 Book of the Year awards, including two for first place. Elsevier's books were honored in the Gerontologic Nursing, Maternal and Child Health, and Critical Care-Emergency Nursing categories.

19 Feb 2013

EMA designates Osiris as Orphan Drug title holder for Prochymal

Osiris Therapeutics, Inc., the leading stem cell company developing and marketing products to treat medical conditions in inflammatory, cardiovascular, orthopedic and wound healing markets, announced today that the European Medicines Agency (EMA) has designated Osiris as the Orphan Drug title holder for Prochymal (remestemcel-L).

19 Feb 2013

TP63 gene correlates significantly with worse prognosis of melanoma

Scientists at Queen Mary, University of London have identified a gene present in some melanoma which appears to make the tumour cells more resistant to treatment, according to research published today in the Journal of Experimental Medicine.

19 Feb 2013

Tranylcypromine may also hold promise in treating sickle cell disease

An antidepressant drug used since the 1960s may also hold promise for treating sickle cell disease, according to a surprising new finding made in mice and human red blood cells by a team from the University of Michigan Medical School.

19 Feb 2013

New regeneration approach could be used for people with bladder issues

A new approach to bladder regeneration is capitalizing on the potential of two distinct cell populations harvested from a patient's healthy bone marrow, a new study reports.

19 Feb 2013

Cholesterol metabolism regulated by bacteria in the small intestine

Researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, show that cholesterol metabolism is regulated by bacteria in the small intestine. These findings may be important for the development of new drugs for cardiovascular disease.

19 Feb 2013

FSH, LH two important hormones that regulate puberty and maturation processes

FSH and LH are two important hormones which regulate the processes of puberty and maturation. These hormones are secreted by the pituitary gland and are transported in the blood to the genitalia, where they regulate maturation.

19 Feb 2013

Researchers design molecules that can stop colon cancer progression

A Basque research consortium has managed to halt the progress of colon cancer and its metastasis in the liver in an experimental model with mice. This advance, that may open a new path for the future treatment of such pathologies, has been achieved by creating molecules which interfere with the adhesion of tumour cells to other cells of the organism. In this way, the molecules halt both the growth of the tumour and the dissemination of the tumour to and its proliferation in other organs.

19 Feb 2013