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Cloud technology helps researchers collect detailed information from cancer cell samples

Storing music and photos on distant computers via "cloud" technology is nothing new. But Johns Hopkins researchers are now using this tactic to collect detailed information from thousands of cancer cell samples. The goal is to help doctors make better predictions about how a patient's illness will progress and what type of treatment will be most effective.

7 Nov 2012

Sperm viability assessed in a number of UK fertility laboratories by using Linkam’s warm stages

Market leaders in temperature controlled microscopy, Linkam Scientific Instruments, have been chosen as suppliers of warm stages to a number of laboratories in the UK for sperm assessment.

From Linkam Scientific Instruments 7 Nov 2012

Treatment with AMG 145 reduces LDL cholesterol

Amgen today announced that results from the LAPLACE-TIMI 57 and MENDEL Phase 2 studies evaluating AMG 145 in hypercholesterolemic patients with or without statins, respectively, showed that treatment with AMG 145 resulted in a statistically significant reduction in low-density lipoprotein (LDL) cholesterol.

7 Nov 2012

Link between SFRP4 protein and risk of type 2 diabetes

When a patient is diagnosed with type 2 diabetes, the disease has usually already progressed over several years and damage to areas such as blood vessels and eyes has already taken place. To find a test that indicates who is at risk at an early stage would be valuable, as it would enable preventive treatment to be put in place.

7 Nov 2012

AIDS Research and Human Retroviruses journal publishes special issue on prevention

The journal of AIDS Research and Human Retroviruses has published a special issue examining the "complex factors involved in the sexual transmission of HIV, the urgent need for new preventive approaches, and the most promising methods currently in development," according to a press release from the publisher, Mary Ann Leibert, Inc.

7 Nov 2012

Drug trio may reduce eliminate cardiac side effects of doxorubicin

Combining cancer medication with a drug for erectile dysfunction and one for heart transplants helped kill cancer cells and protected the heart from damage, in a study presented at the American Heart Association's Scientific Sessions 2012.

7 Nov 2012

Alpha-herpesvirus axon-to-cell spread involves limited virion transmission

New research suggests that just one or two individual herpes virus particles attack a skin cell in the first stage of an outbreak, resulting in a bottleneck in which the infection may be vulnerable to medical treatment.

7 Nov 2012

Taiho Pharmaceutical announces early stage data for eight novel oncology compounds

Taiho Pharmaceutical Co., Ltd., the developer of the first orally available fluorouracil (FU) Chemotherapeutic treatment (TS-1/S-1), is presenting early stage data for eight novel oncology compounds, including potential first-in-class therapies.

7 Nov 2012

Researchers develop new kind of intracranial pressure sensor

An increase in cerebral pressure may cause dementia and could destroy the brain. Companies have been seeking to find monitoring sensors that can be implanted into the brain, and read from outside the body. A tiny sensor may provide the help needed.

7 Nov 2012

Loyola announces 2012 Junior and Senior Scientist of the Year during St. Albert's Day

Katherine L. Knight, PhD, one of the nation's leading immune system researchers, has been named 2012 Senior Scientist of the Year at Loyola University Chicago Stritch School of Medicine. Sakthivel Sadayappan, PhD, FAHA, who is doing groundbreaking research on a protein that is critical for the normal functioning of the heart, has been named 2012 Junior Scientist of the Year.

7 Nov 2012

Scientists identify group of small molecules that interfere with polyphosphate activity

Scientists have identified a group of small molecules that interfere with the activity of a compound that initiates multiple steps in blood clotting, including those that lead to the obstruction of veins or arteries, a condition called thrombosis. Blocking the activity of this compound, polyphosphate, could treat thrombosis with fewer bleeding side effects than the drugs that are currently on the market.

7 Nov 2012

Positive results from BioCardia's Helical Infusion System Phase 1/2 trial on ischemic cardiomyopathy

BioCardia, Inc., focused on regenerative biologic therapies for cardiovascular disease, today announced positive results from a Phase 1/2 heart failure trial using the Company's Helical Infusion System, comprising the Helical Infusion System Catheter and Morph Vascular Access Catheter, to deliver allogeneic, or "off-the-shelf," and autologous, or from the treated patient, mesenchymal (adult) stem cells (MSCs) via transendocardial injection.

7 Nov 2012

Researchers succeed in teaching computers how to identify commonalities in DNA sequences

Johns Hopkins researchers have succeeded in teaching computers how to identify commonalities in DNA sequences known to regulate gene activity, and to then use those commonalities to predict other regulatory regions throughout the genome. The tool is expected to help scientists better understand disease risk and cell development.

7 Nov 2012

FDA grants Priority Review to ImmunoGen’s trastuzumab emtansine BLA

ImmunoGen, Inc., a biopharmaceutical company that develops anticancer products using its Targeted Antibody Payload (TAP) technology and antibody expertise, today announced that Genentech, a member of the Roche Group, has disclosed that the U.S. Food and Drug Administration (FDA) has officially accepted the Biologics License Application (BLA) for trastuzumab emtansine and granted it Priority Review.

7 Nov 2012

Researchers show how bacteria control processes in human cells

Bacteria can talk to each other via molecules they themselves produce. The phenomenon is called quorum sensing, and is important when an infection propagates. Now, researchers at Link-ping University in Sweden are showing how bacteria control processes in human cells the same way.

6 Nov 2012

FDA approves Pfizer’s XELJANZ to treat rheumatoid arthritis

Pfizer Inc. has received approval from the U.S. Food and Drug Administration (FDA) for XELJANZ (tofacitinib citrate) 5 mg twice daily for the treatment of adults with moderately to severely active rheumatoid arthritis (RA) who have had an inadequate response or intolerance to methotrexate.

6 Nov 2012

$Cryopraxis/CellPraxis initiates recruitment in ReACT Phase III trial for refractory angina$

Cryopraxis/CellPraxis initiates recruitment in ReACT Phase III trial for refractory angina

Cryopraxis/CellPraxis aims to start patient recruitment for its Phase III Refractory Angina Cell Therapy Brazilian arm clinical trial by the end of 2012 or early 2013.

6 Nov 2012

Receptor expression sheds light on nasal polyposis

The increased expression of a leukotriene receptor and a glucocorticoid receptor may contribute to the development of nasal polyposis, report researchers.

6 Nov 2012

Testosterone exposure early in life can have lasting impact on brain function and behavior

New findings led by Dr. Michael Lombardo, Prof. Simon Baron-Cohen and colleagues at the University of Cambridge indicate that testosterone levels early in fetal development influence later sensitivity of brain regions related to reward processing and affect an individual's susceptibility to engage in behavior, that in extremes, are related to several neuropsychiatric conditions that asymmetrically affect one sex more than the other.

6 Nov 2012

New test device allows 'more real-life modeling' of contact lens wear

Modern contact lens materials are prone to drying when exposed to air, which contributes to the buildup of deposits on contact lenses, according to a study - "The Impact of Intermittent Air Exposure on Lipid Deposition", appearing in the November issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

6 Nov 2012

Cell News and Research

Cloud technology helps researchers collect detailed information from cancer cell samples

Sperm viability assessed in a number of UK fertility laboratories by using Linkam’s warm stages

Treatment with AMG 145 reduces LDL cholesterol

Link between SFRP4 protein and risk of type 2 diabetes

AIDS Research and Human Retroviruses journal publishes special issue on prevention

Drug trio may reduce eliminate cardiac side effects of doxorubicin

Alpha-herpesvirus axon-to-cell spread involves limited virion transmission

Taiho Pharmaceutical announces early stage data for eight novel oncology compounds

Researchers develop new kind of intracranial pressure sensor

Loyola announces 2012 Junior and Senior Scientist of the Year during St. Albert's Day

Scientists identify group of small molecules that interfere with polyphosphate activity

Positive results from BioCardia's Helical Infusion System Phase 1/2 trial on ischemic cardiomyopathy

Researchers succeed in teaching computers how to identify commonalities in DNA sequences

FDA grants Priority Review to ImmunoGen’s trastuzumab emtansine BLA

Researchers show how bacteria control processes in human cells

FDA approves Pfizer’s XELJANZ to treat rheumatoid arthritis

Cryopraxis/CellPraxis initiates recruitment in ReACT Phase III trial for refractory angina

Receptor expression sheds light on nasal polyposis

Testosterone exposure early in life can have lasting impact on brain function and behavior

New test device allows 'more real-life modeling' of contact lens wear

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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