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Ajuba protein plays a central role in regulating function of heart stem cells

It is not unusual for babies to be born with congenital heart defects. This is because the development of the heart in the embryo is a process which is not only extremely complex, but also error-prone. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now identified a key molecule that plays a central role in regulating the function of stem cells in the heart.

14 Jul 2012

New paper documents discovery of novel lipids, including MC3

Alnylam Pharmaceuticals, a leading RNAi therapeutics company, and collaborators announced today the publication of a scientific paper documenting the discovery of novel lipids used in second generation lipid nanoparticles (LNPs) for systemic delivery of RNAi therapeutics.

14 Jul 2012

Sandia researchers develop SpinDx medical diagnostic tool

Researchers at Sandia National Laboratories have developed a lab-on-a-disk platform that they believe will be faster, less expensive and more versatile than similar medical diagnostic tools.

14 Jul 2012

Obesity-fighting tissue in humans is actually not quite brown, says study

The calorie-burning and heat-generating brown fat found in full-grown humans is actually not quite brown; it's beige. So says a new study reported on July 12th in the journal Cell, a Cell Press publication, in which researchers fully characterize this promising obesity-fighting tissue in both mice and humans for the first time.

14 Jul 2012

Researchers define interaction between two essential proteins that control inflammation

Researchers at the IRCM, led by geneticist Dr. Jacques Drouin, recently defined the interaction between two essential proteins that control inflammation.

14 Jul 2012

Paper describes novel psychotherapeutic approach in a boy with Asperger's syndrome

This paper reports a stable improvement in social skills in a 15-year-old boy diagnosed with Asperger's syndrome (AS), after an outpatient treatment with Social Effectiveness Therapy for Children and Adolescents (SET-C), a specific and intensive type of social skill training. Its effectiveness should be further tested in randomized controlled and long-term follow-up studies.

14 Jul 2012

Identification of IL-9 antitumor activity in melanoma

High expression of interleukin -9 in immune cells inhibits growth of melanoma, show study findings suggesting a role for this T-cell cytokine in tumor suppression.

13 Jul 2012

ACT treats fourth patient in U.S. clinical trial for Stargardt's Macular Dystrophy

Advanced Cell Technology, Inc., a leader in the field of regenerative medicine, today announced treatment of the fourth patient, the first in the second patient cohort, in its U.S. clinical trial for Stargardt's Macular Dystrophy (SMD).

13 Jul 2012

Scientists isolate new type of energy-burning fat cell

Scientists at Dana-Farber Cancer Institute have isolated a new type of energy-burning fat cell in adult humans which they say may have therapeutic potential for treating obesity.

13 Jul 2012

OncoMed commences dosing in OMP-54F28 Phase I clinical trial for advanced solid tumor cancers

OncoMed Pharmaceuticals, Inc., a clinical-stage company developing novel therapeutics that target cancer stem cells, or tumor-initiating cells, today announced that patient dosing has begun in a Phase I clinical trial of OMP-54F28 in patients with advanced solid tumor cancers.

13 Jul 2012

Discovery sheds light on why human body is unable to fight off HIV infection

University of Washington researchers have made a discovery that sheds light on why the human body is unable to adequately fight off HIV infection.

13 Jul 2012

High-risk HPV may increase chances of second malignancy in oral cancer

The proportion of oral squamous cell carcinoma patients infected with the human papillomavirus could be around a third, with high-risk versions of the virus accounting for almost three-quarters of those affected, indicate Taiwanese study results.

12 Jul 2012

Eosinophil count predicts mortality risk following heart procedure

Study findings suggest that eosinophil count predicts mortality risk in patients undergoing percutaneous coronary intervention.

12 Jul 2012

Eisai, Verastem partner for next-generation of small molecule Wnt inhibitors

Verastem, Inc., a biopharmaceutical company focused on discovering and developing drugs to treat breast and other cancers by targeting cancer stem cells, announced a research collaboration with Eisai for the next-generation of small molecule Wnt inhibitors.

12 Jul 2012

Maraviroc reduces incidence of GvHD in blood cancer patients after bone marrow transplantation

An HIV drug that redirects immune cell traffic significantly reduces the incidence of a dangerous complication that often follows bone marrow transplants for blood cancer patients, according to research from the Perelman School of Medicine at the University of Pennsylvania that will be published today in the New England Journal of Medicine.

12 Jul 2012

Scientists capture high-quality images of immune cell trafficking in a beating heart

Blood flow to the heart often is interrupted during a heart attack or cardiac surgery. But when blood flow resumes, the heart may still falter. That's because collateral damage can occur as blood re-enters the heart, potentially slowing recovery and causing future cardiac troubles.

12 Jul 2012

PGC-1alpha and TFEB provide two new therapeutic targets for Huntington's disease

In a paper published in the July 11 online issue of Science Translational Medicine, researchers at the University of California, San Diego School of Medicine have identified two key regulatory proteins critical to clearing away misfolded proteins that accumulate and cause the progressive, deadly neurodegeneration of Huntington's disease.

12 Jul 2012

Manipulating retinal recipient microenvironment impacts photoreceptor cell transplantation

A research team in the United Kingdom has found that insulin-like growth factor (IGF1) impacts cell transplantation of photoreceptor precursors by manipulating the retinal recipient microenvironment, enabling better migration and integration of the cells into the adult mouse retina.

12 Jul 2012

Two new NSCA journal apps for the iPad are now available

The National Strength and Conditioning Association (NSCA) now offers digital access to its official peer-reviewed journals with the introduction of iPad editions for Strength and Conditioning Journal and Journal of Strength and Conditioning Research.

12 Jul 2012

Communication between brain and muscle cells is short-lived without LRP4 protein

Communication between the brain and muscle must be strong for us to eat, breathe or walk. Now scientists have found that a protein known to be on the surface of muscle cells must be present in both tissues to ensure the conversation is robust.

12 Jul 2012

Cell News and Research

Ajuba protein plays a central role in regulating function of heart stem cells

New paper documents discovery of novel lipids, including MC3

Sandia researchers develop SpinDx medical diagnostic tool

Obesity-fighting tissue in humans is actually not quite brown, says study

Researchers define interaction between two essential proteins that control inflammation

Paper describes novel psychotherapeutic approach in a boy with Asperger's syndrome

Identification of IL-9 antitumor activity in melanoma

ACT treats fourth patient in U.S. clinical trial for Stargardt's Macular Dystrophy

Scientists isolate new type of energy-burning fat cell

OncoMed commences dosing in OMP-54F28 Phase I clinical trial for advanced solid tumor cancers

Discovery sheds light on why human body is unable to fight off HIV infection

High-risk HPV may increase chances of second malignancy in oral cancer

Eosinophil count predicts mortality risk following heart procedure

Eisai, Verastem partner for next-generation of small molecule Wnt inhibitors

Maraviroc reduces incidence of GvHD in blood cancer patients after bone marrow transplantation

Scientists capture high-quality images of immune cell trafficking in a beating heart

PGC-1alpha and TFEB provide two new therapeutic targets for Huntington's disease

Manipulating retinal recipient microenvironment impacts photoreceptor cell transplantation

Two new NSCA journal apps for the iPad are now available

Communication between brain and muscle cells is short-lived without LRP4 protein

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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