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Scientists show how RET gene in breast cancer cells responds to estrogen

Using human breast cancer cells and the protein that causes fireflies to glow, a Johns Hopkins team has shed light on why some breast cancer cells become resistant to the anticancer effects of the drug tamoxifen. The key is a discovery of two genetic "dimmer switches" that apparently control how a breast cancer gene responds to the female hormone estrogen.

28 Jul 2011

Chronic psychological stress linked to increased risk of Alzheimer's

Chronic psychological stress throughout a lifespan might increase an individual's risk for Alzheimer's and dementia later in life, according to research from the Emma Eccles Jones College of Education and Human Services at Utah State University.

28 Jul 2011

Noninvasive brain computer interface could turn thoughts into motion

"Brain cap" technology being developed at the University of Maryland allows users to turn their thoughts into motion. Associate Professor of Kinesiology José 'Pepe' L. Contreras-Vidal and his team have created a non-invasive, sensor-lined cap with neural interface software that soon could be used to control computers, robotic prosthetic limbs, motorized wheelchairs and even digital avatars.

28 Jul 2011

Blueberries can help prevent cell damage linked to cancer

Blueberries are among the nutrient-rich foods being studied by UAB Comprehensive Cancer Center investigators exploring the link between disease and nutrition. Dieticians there say as little as a cup a day can help prevent cell damage linked to cancer.

28 Jul 2011

IRCM geneticists discover an unsuspected organization of pituitary cells

A team of geneticists at the Institut de recherches cliniques de Montr-al (IRCM), directed by Dr. Jacques Drouin, made an unexpected discovery on hormone secretion. Contrary to common belief, the researchers found that pituitary cells are organized in structured networks. The scientific breakthrough was published yesterday by the scientific journal Proceedings of the National Academy of Sciences.

28 Jul 2011

Puget Sound Blood Center, Seattle Children's inaugurate new on-site lab

Today, Seattle Children's and Puget Sound Blood Center opened a new blood laboratory to serve Children's patients exclusively. Located within Seattle Children's main campus and staffed by Puget Sound Blood Center employees 24 hours every day of the year, the facility will bring the lab closer to the patient.

28 Jul 2011

Invadopodia could help survival of cancer cells

Delicate, threadlike protrusions used by cancer cells when they invade other tissues in the body could also help them escape control mechanisms supposed to eliminate them, a research group led by led by Bradley Davidson in the University of Arizona's department of molecular and cellular biology reports in Nature Cell Biology.

28 Jul 2011

Insect virus holds key to safer stem cell therapy: Singapore scientists

The future of regenerative medicine lies in harnessing the potential of the human body to renew and repair itself. Now, scientists at the Institute of Bioengineering and Nanotechnology (IBN), the world's first bioengineering and nanotechnology research institute, have developed a new genetic engineering technique that promises safer stem cell therapy for cancer patients. Using an insect virus, the team of researchers successfully inserted a therapeutic gene into a safe site in the DNA of human embryonic stem cells without compromising the functionality of the engineered cells.

28 Jul 2011

U.S. Judge approves federal funding for embryonic research

Federal funding of human embryonic stem cell (hESC) research is now legal in the United States. Chief judge of the US District Court for the District of Columbia Royce Lamberth has ruled on the case Sherley et al. v. Sebelius, in favor of hESC research. This overturns an existing law that prohibits the government from funding research that destroys the embryo.

27 Jul 2011

No link between cell phone use and increased risk for brain cancer: European study

A new study that looked at cell phone users under the age of 20 found no link between cell phone use and an increased risk for brain cancer. Researchers from the Swiss Tropical and Public Health Institute in Basel, Switzerland, studied data collected in Norway, Denmark, Sweden and Switzerland.

27 Jul 2011

FDA accepts peginesatide NDA for anemia associated with CKD

Affymax, Inc. and Takeda Global Research & Development Center, Inc., U.S., today announced that the U.S. Food and Drug Administration (FDA) accepted for review the New Drug Application (NDA) for peginesatide (formerly known as Hematide™) for the treatment of anemia associated with chronic kidney disease (CKD) in adult patients on dialysis.

27 Jul 2011

Recruitment complete in Aeterna Zentaris' perifosine Phase 3 trial for advanced colorectal cancer

Aeterna Zentaris Inc. today announced the completion of patient recruitment for the ongoing Phase 3 trial with perifosine in refractory advanced colorectal cancer.

27 Jul 2011

Carcinogenesis is just another form of speciation, proposes new theory

Cancer patients may view their tumors as parasites taking over their bodies, but this is more than a metaphor for Peter Duesberg, a molecular and cell biology professor at the University of California, Berkeley.

27 Jul 2011

Scientists reveal complete three-dimensional atomic structure of an activated GPCR

G protein-coupled receptors (GPCRs) are popular drug targets, accounting for about one-third of approved drugs and many hundreds of drugs currently in development. They act as molecular switches that transduce extracellular signals by activating heterotrimeric G proteins located at the inside of the cell.

27 Jul 2011

Study reveals several compounds that block cancer cell invasion

Metastasis-the spread of cancer from the place where it first started to another place in the body-is the most common reason that cancer treatments fail. To metastasize, some types of cancer cells rely on invadopodia, cellular membrane projections that act like feet, helping them "walk" away from the primary tumor and invade surrounding tissues.

27 Jul 2011

Positive results from phase Ib/IIa trial of novel molecular technique for Duchenne muscular dystrophy

A molecular technique originally developed at the University of North Carolina at Chapel Hill has taken one step closer to becoming a treatment for the devastating genetic disease Duchenne muscular dystrophy.

27 Jul 2011

New Penn Center for Orphan Disease Research and Therapy

The Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania announces the launching of a first-of-its-kind interdisciplinary center focused on discovering novel treatments for orphan diseases.

27 Jul 2011

Athletic trainers and coaches bear major responsibility for preventing deaths

Colleges and high schools must follow an active strategy to preventing deaths among student athletes from exertional heat stroke (EHS) and other causes, according to an editorial in a recent issue of The Journal of Strength and Conditioning Research, official research journal of the National Strength and Conditioning Association.

27 Jul 2011

Novel blood-cleaning procedure allows receipt of transplant from different blood type donor

St. Michael's Hospital today became the first in North America to use a novel blood-cleaning procedure for a kidney patient that will allow him to receive a transplant from a donor with a different blood type.

27 Jul 2011

New silicone chip could make genetic analysis far more sensitive, rapid, and cost-effective

UBC researchers have invented a silicone chip that could make genetic analysis far more sensitive, rapid, and cost-effective by allowing individual cells to fall into place like balls in a pinball machine.

27 Jul 2011